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在“Elsevier电子期刊”中，命中：751条，耗时：0.0459763 秒

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1.Analogs of farnesyl diphosphate alter CaaX substrate specificity and reactions rates of protein farnesyltransferase

作者：Benjamin C. Jennings^a ; Amy M. Danowitz^b ; Yen-Chih Wang^c ; Richard A. Gibbs^d ; ^&dagger ; ; Mark D. Distefano^c ; ^e ; Carol A. Fierke^a ; ^f ; ^{fierke@umich.edu" class="auth_mail" title="E-mail the corresponding author}

关键词：Protein farnesylation ; Protein prenylation ; Click chemistry ; Substrate analogs ; Post-translational modification

刊名：Bioorganic & Medicinal Chemistry Letters

出版年：2016

2.Exploration of GGTase-I substrate requirements. Part 2: Synthesis and biochemical analysis of novel saturated geranylgeranyl diphosphate analogs

作者：Kayla J. Temple^a ; ^b ; ^{kayla.temple@vanderbilt.edu" class="auth_mail" title="E-mail the corresponding author} ; Elia N. Wright^c ; Carol A. Fierke^c ; ^d ; Richard A. Gibbs^a ; ^b

关键词：Protein prenylation ; Saturated GGPP analogs ; Farnesylation ; Geranylgeranylation ; Isoprenoid synthesis

刊名：Bioorganic & Medicinal Chemistry Letters

出版年：2016

3.Exploration of GGTase-I substrate requirements. Part 1: Synthesis and biochemical evaluation of novel aryl-modified geranylgeranyl diphosphate analogs

作者：Kayla J. Temple^a ; ^b ; ^{kayla.temple@vanderbilt.edu" class="auth_mail" title="E-mail the corresponding author} ; Elia N. Wright^c ; Carol A. Fierke^c ; ^d ; Richard A. Gibbs^a ; ^b

关键词：Geranylgeranylation ; Aryl-modified GGPP analogs ; GGTase-I ; Post-translational modification ; Protein prenylation

刊名：Bioorganic & Medicinal Chemistry Letters

出版年：2016

4.LAT-1 activity of meta-substituted phenylalanine and tyrosine analogs

作者：Evan Augustyn^a ; ^&dagger ; ; Karissa Finke^a ; ^&dagger ; ; Arik A. Zur^b ; ^&dagger ; ; ^{riko.zur@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Logan Hansen^a ; Nathan Heeren^a ; Huan-Chieh Chien^b ; Lawrence Lin^b ; Kathleen M. Giacomini^b ; Claire Colas^c ; Avner Schlessinger^c ; Allen A. Thomas^a ; ^{thomasaa@unk.edu" class="auth_mail" title="E-mail the corresponding author}

关键词：SLC7A5 ; Amino acid ; Negishi coupling ; Transporter substrate ; Transporter inhibitor

刊名：Bioorganic & Medicinal Chemistry Letters

出版年：2016

5.Cooperative effects of fibronectin matrix assembly and initial cell-substrate adhesion strength in cellular self-assembly

作者：James R. Brennan^a ; Denise C. Hocking^a ; ^b ; ^{denise_hocking@urmc.rochester.edu" class="auth_mail" title="E-mail the corresponding author}

关键词：ECM ; extracellular matrix ; FNIII ; fibronectin type III repeat ; GST ; glutathione-S-transferase ; FN ; fibronectin

刊名：Acta Biomaterialia

出版年：2016

6.Synthesis and evaluation of an alkyne-modified ATP analog for enzymatic incorporation into RNA

作者：Yuxuan Zheng ; Peter A. Beal ; ^{pabeal@ucdavis.edu" class="auth_mail" title="E-mail the corresponding author}

关键词：ATP analogs ; T7 transcription ; Polyadenylation ; Cellular RNA labeling ; Click chemistry

刊名：Bioorganic & Medicinal Chemistry Letters

出版年：2016

7.Substrate screening of amino transaminase for the synthesis of a sitagliptin intermediate

作者：Anwei Hou^a ; Zixin Deng^a ; ^b ; Hongmin Ma^a ; ^{hongminma@whu.edu.cn" class="auth_mail" title="E-mail the corresponding author} ; Tiangang Liu^a ; ^b ; ^{liutg@whu.edu.cn" class="auth_mail" title="E-mail the corresponding author}

关键词：Aminotransferase ; Enzymatic reaction ; Sitagliptin ; Product inhibition

刊名：Tetrahedron

出版年：2016

8.Isomeric iodinated analogs of nimesulide: Synthesis, physicochemical characterization, cyclooxygenase-2 inhibitory activity, and transport across Caco-2 cells

作者：Yumi Yamamoto^a ; ^{yumi-y@tohoku-mpu.ac.jp" class="auth_mail" title="E-mail the corresponding author} ; Jun Arai^a ; Takuya Hisa^a ; Yohei Saito^a ; Takahiro Mukai^b ; Takashi Ohshima^c ; Minoru Maeda^d ; Fumihiko Yamamoto^a

关键词：Nimesulide ; COX-2 ; Iodine ; Caco-2 cell monolayers ; Lipophilicity ; Blood&ndash ; brain barrier

刊名：Bioorganic & Medicinal Chemistry

出版年：2016

9.Stereoselective total synthesis of (±)-parthenolide and (±)-7-epi-parthenolide

作者：Liang Li ; Xuan Pan ; Baohe Guan ; Zhanzhu Liu ; ^{liuzhanzhu@imm.ac.cn" class="auth_mail" title="E-mail the corresponding author}

关键词：Parthenolide ; Substrate-controlled ; Stereoselective ; Stereoisomers

刊名：Tetrahedron

出版年：2016

10.Regulating effect of β-ketoacyl synthase domain of fatty acid synthase on fatty acyl chain length in de novo fatty acid synthesis

作者：Wei Cui^a ; ^{cuiwei@ucas.ac.cn" class="auth_mail" title="E-mail the corresponding author} ; Yan Liang^b ; ^{yanliang@cupes.edu.cn" class="auth_mail" title="E-mail the corresponding author} ; Weixi Tian^c ; ^{tianweixi@ucas.ac.cn" class="auth_mail" title="E-mail the corresponding author} ; Mingjuan Ji^a ; ^{jmj@ucas.ac.cn" class="auth_mail" title="E-mail the corresponding author} ; Xiaofeng Ma^c ; ^{maxiaofeng@ucas.ac.cn" class="auth_mail" title="E-mail the corresponding author}

关键词：Fatty acid synthase (FAS) ; β-Ketoacyl synthase (KS) ; Binding free energy calculation ; Fatty acid production ratio ; Chain length

刊名：Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids

出版年：2016

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