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Elsevier电子期刊(18)

在“Elsevier电子期刊”中，命中：18条，耗时：0.0309817 秒

在所有数据库中总计命中：45条

1.One-pot synthesis of podophyllotoxin-thiourea congeners by employing NH₂SO₃H/NaI: Anticancer activity, DNA topoisomerase-II inhibition, and apoptosis inducing agents

作者：Nagula Shankaraiah^a ; ^{shankar@niperhyd.ac.in" class="auth_mail" title="E-mail the corresponding author} ; Niggula Praveen Kumar^a ; ^c ; Suresh Babu Amula^a ; Shalini Nekkanti^a ; Manish Kumar Jeengar^b ; V.G.M. Naidu^b ; ^{vgmnaidu@niperhyd.ac.in" class="auth_mail" title="E-mail the corresponding author} ; T. Srinivasa Reddy^c ; Ahmed Kamal^a ; ^c ; ^{ahmedkamal@iict.res.in" class="auth_mail" title="E-mail the corresponding author}

关键词：Azido reduction ; Sulfamic acid ; Sodium iodide ; Podophyllotoxin ; Thiourea ; Cell cycle analysis ; Cytotoxicity ; Topoisomerase-II inhibition ; Molecular modeling

刊名：Bioorganic & Medicinal Chemistry Letters

出版年：2015

2.Curcumin-inspired cytotoxic 3,5-bis(arylmethylene)-1-(N-(ortho-substituted aryl)maleamoyl)-4-piperidones: A novel group of topoisomerase II alpha inhibitors

作者：Amitabh Jha^a ; ^{ajha@acadiau.ca" class="auth_mail" title="E-mail the corresponding author} ; Katherine M. Duffield^a ; Matthew R. Ness^a ; Sujatha Ravoori^a ; Gabrielle Andrews^a ; Khushwant S. Bhullar^b ; H.P. Vasantha Rupasinghe^b ; Jan Balzarini^c

关键词：Curcumin analogs ; 4-Piperidones ; Maleamic acids ; Cytostatic activity ; QSAR ; Topoisomerase II伪 inhibition

刊名：Bioorganic & Medicinal Chemistry

出版年：2015

3.Newly discovered chroman-2,4-diones neutralize the in vivo DNA damage induced by alkylation through the inhibition of Topoisomerase II伪: A story behind the molecular modeling approach

关键词：2a ; (E)-3-(1-(2-aminoethylamino)ethylidene)chroman-2 ; 4-dione ; 2b ; (E)-3-(1-(2-hydroxyethylamino)ethylidene)chroman-2 ; 4-dione ; 2c ; (E)-3-(1-(2-mercaptoethylamino)ethylidene)chroman-2 ; 4-dione ; 2d ; (E)-3-(1-(2-(methylamino)ethylamino)ethylidene)chroman-2 ; 4-dione ; 2e ; (3E ; 3&prime ; E)-3 ; 3&prime ; -(1 ; 1&prime ; -(propane-1 ; 3-diylbis(azanediyl))bis(ethan-1-yl-ylidene))dichroman-2 ; 4-dione ; 2f ; (3E ; 3&prime ; E)-3 ; 3&prime ; -(1 ; 1&prime ; -(ethane-1 ; 2-diylbis(azanediyl))bis(ethan-1-yl-1-ylidene))dichroman-2 ; 4-dione

刊名：Biochemical Pharmacology

出版年：2015

4.Design and synthesis of 2-phenylnaphthalenoids and 2-phenylbenzofuranoids as DNA topoisomerase inhibitors and antitumor agents

作者：Huilin Hao^a ; Wang Chen^a ; Jing Zhu^b ; Chunhua Lu^a ; Yuemao Shen^a ; ^b ; ^{yshen@sdu.edu.cn" class="auth_mail" title="E-mail the corresponding author}

关键词：2-Phenylnaphthalenoids ; 2-Phenylbenzofuranoids ; Topoisomerase II伪 inhibitor ; Antitumor

刊名：European Journal of Medicinal Chemistry

出版年：2015

5.A high-throughput fluorescence anisotropy-based assay for human topoisomerase II 尾-catalyzed ATP-dependent supercoiled DNA relaxation

作者：Adam B. Shapiro ; Caroline A. Austin

关键词：Topoisomerase ; Topoisomerase II伪 ; Topoisomerase II尾 ; High-throughput assay ; Fluorescence anisotropy

刊名：Analytical Biochemistry

出版年：1 March, 2014

6.Structural determinants of the catalytic inhibition of human topoisomerase II伪 by salicylate analogs and salicylate-based drugs

作者：Jason T. Bau ; Ebba U. Kurz ; ^{kurz@ucalgary.ca" class="auth_mail}

关键词：2-FBA ; 2-fluorobenzoate ; 2-MBA ; 2-methylbenzoate ; 5-ASA ; 5-aminosalicylic acid ; ASA ; acetylsalicylic acid ; DHBA ; dihydroxybenzoate ; HBA ; hydroxybenzoate ; ICE ; in vivo complex of enzyme ; kDNA ; kinetoplast DNA ; topo II ; topoisomerase II ; THBA ; trihydroxybenzoate

刊名：Biochemical Pharmacology

出版年：15 June 2014

7.DNA topoisomerases in mtDNA maintenance and ageing

作者：Stefan Sobek ; Fritz Boege ; ^{boege@med.uni-duesseldorf.de" class="auth_mail}

关键词：AMPK ; AMP-dependent protein kinase ; AMPK伪2 ; alpha-subunit of AMP-dependent protein kinase ; MEFs ; Murine embryonic fibroblasts ; mtDNA ; mitochondrial DNA ; mTOR ; Mammalian target of rapamycin ; ROS ; Reactive oxygen species ; TFAM ; Mitochondrial transcription factor A ; TOP1 ; DNA topoisomerase I ; TOP1MT ; Mitochondrial topoisomerase I ; TOP2 ; DNA topoisomerase II ; TOP2A ; topoisomerase II伪 ; TOP2B ; DNA topoisomerase II尾 ; TOP3A ; DNA topoisomerase III伪

刊名：Experimental Gerontology

出版年：August 2014

8.Induction of apoptosis in cholangiocarcinoma by an andrographolide analogue is mediated through topoisomerase II alpha inhibition

作者：Jintapat Nateewattana ; Suman Dutta ; Somrudee Reabroi ; Rungnapha Saeeng ; Sakkasem Kasemsook ; Arthit Chairoungdua ; Jittima Weerachayaphorn ; Sopit Wongkham ; Pawinee Piyachaturawat

关键词：Andrographolide analogue ; Apoptosis ; Cholangiocarcinoma ; KKU-M213 cell line ; Topoisomerase II 伪

刊名：European Journal of Pharmacology

出版年：15 January, 2014

9.Rational design and synthesis of topoisomerase I and II inhibitors based on oleanolic acid moiety for new anti-cancer drugs

作者：Ahmed Ashour ; Saleh El-Sharkawy ; Mohamed Amer ; Fatma Abdel Bar ; Yoshinori Katakura ; Tomofumi Miyamoto ; Nozomi Toyota ; Tran Hai Bang ; Ryuichiro Kondo ; Kuniyoshi Shimizu

关键词：Oleanolic acid ; Topoisomerase I and II ; Inhibitor ; SARS

刊名：Bioorganic and Medicinal Chemistry

出版年：1 January, 2014

10.Tyrosyl-DNA-phosphodiesterase I (TDP1) participates in the removal and repair of stabilized-Top2伪 cleavage complexes in human cells

作者：Miguel Angel Borda¹ ; Micaela Palmitelli¹ ; Gustavo Verón ; Marcela Gonzá ; lez-Cid ; Marcelo de Campos Nebel ; ^{mnebel@hematologia.anm.edu.ar" class="auth_mail" title="E-mail the corresponding author}

关键词：Topoisomerase II-mediated DNA damage ; DNA double strand break repair ; Tyrosyl-DNA-phosphodiesterase I ; Genome instability

刊名：Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

出版年：2015

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