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Wiley电子期刊(80)	SpringerLink电子期刊(1954)	NATURE电子期刊(38)	ACS电子期刊(227)
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在“Elsevier电子期刊”中，命中：3,497条，耗时：0.1069187 秒

在所有数据库中总计命中：5,800条

1.Phase 2 Study of Erlotinib in Combination With Linsitinib (OSI-906) or Placebo in Chemotherapy-Naive Patients With Non-Small-Cell Lung Cancer and Activating Epidermal Growth Factor Receptor Mutations

作者：Natasha B. Leighl¹ ; Naiyer A. Rizvi² ; Lopes Gilberto de Lima Jr.³ ; ⁴ ; Wichit Arpornwirat⁵ ; Charles M. Rudin⁶ ; Alberto A. Chiappori⁷ ; Myung-Ju Ahn⁸ ; Laura Q.M. Chow⁹ ; Lyudmila Bazhenova¹⁰ ; Arunee Dechaphunkul¹¹ ; Patrapim Sunpaweravong¹² ; Keith Eaton¹³ ; ¹⁴ ; Jihong Chen¹⁵ ; Sonja Medley¹⁵ ; Srinivasu Poondru¹⁵ ; Margaret Singh¹⁵ ; Joyce Steinberg¹⁵ ; Rosalyn A. Juergens¹⁶ ; ^{juergensr@hhsc.ca} ; Shirish M. Gadgeel¹⁷ ; ¹⁸

关键词：Combination ; Epidermal growth factor receptor inhibitor ; First-line therapy ; Insulin-like growth factor-1 inhibitor ; Tyrosine kinase inhibitor

刊名：Clinical Lung Cancer

出版年：2017

2.Treatment Rationale and Study Design for the RELAY Study: A Multicenter, Randomized, Double-Blind Study of Erlotinib With Ramucirumab or Placebo in Patients With Epidermal Growth Factor Receptor Mutation-Positive Metastatic Non-Small-Cell Lung Cancer

作者：Edward B. Garon¹ ; Martin Reck² ; Luis Paz-Ares³ ; Santiago Ponce³ ; Jesus Corral Jaime⁴ ; Oscar Juan⁵ ; Ernest Nadal⁶ ; Pablo Lee⁷ ; Rita Dalal⁷ ; Jingyi Liu⁸ ; Shuang He⁸ ; Joseph Treat⁸ ; Kazuhiko Nakagawa⁹ ; ^{nakagawa@med.kindai.ac.jp}

关键词：Epidermal growth factor receptor mutation ; Erlotinib ; Non-small cell lung cancer ; Ramucirumab ; RELAY trial

刊名：Clinical Lung Cancer

出版年：2017

3.Discovery and preclinical evaluation of 7-benzyl-N-(substituted)-pyrrolo[3,2-d]pyrimidin-4-amines as single agents with microtubule targeting effects along with triple-acting angiokinase inhibition as antitumor agents

作者：Roheeth Kumar Pavana^a ; Shruti Choudhary^a ; Anja Bastian^b ; Michael A. Ihnat^c ; Ruoli Bai^d ; Ernest Hamel^d ; Aleem Gangjee^a ; ^{gangjee@duq.edu}

关键词：AA ; antiangiogenic agents ; MTA ; microtubule targeting agents ; VEGFR-2 ; vascular endothelial growth factor receptor-2 ; PDGFR-β ; platelet-derived growth factor receptor-β ; CAM ; chorioallantoic membrane ; CA ; combretastatin A-4 ; Pgp ; P-glycoprotein ; EGFR ; epidermal growth factor receptor ; TBS ; Tris-buffered saline ; HRP ; horseradish peroxidase ; PY ; phosphotyrosine

刊名：Bioorganic & Medicinal Chemistry

出版年：2017

4.Epidermal growth factor receptor signaling promotes metastatic prostate cancer through microRNA-96-mediated downregulation of the tumor suppressor ETV6

作者：Yuan-Chin Tsai^a ; Wei-Yu Chen^b ; ^c ; Man Kit Siu^a ; ^d ; Hong-Yuan Tsai^a ; Juan Juan Yin^e ; Jiaoti Huang^f ; Yen-Nien Liu^a ; ^{liuy@tmu.edu.tw" class="auth_mail" title="E-mail the corresponding author}

关键词：ETV6 ; Epidermal growth factor receptor (EGFR) ; microRNA (miR)-96 ; Prostate cancer ; Bone metastasis

刊名：Cancer Letters

出版年：2017

5.The marine-derived pachycladin diterpenoids as novel inhibitors of wild-type and mutant EGFR

作者：Mohamed M. Mohyeldin ^{mohyelmm@warhawks.ulm.edu} ; Mohamed R. Akl ^{mohamedreda_pharmacy@yahoo.com} ; Abu Bakar Siddique ; Hossam M. Hassan¹ ; ^{abuh20050@yahoo.com} ; Khalid A. El Sayed ; ^{elsayed@ulm.edu}

关键词：ATCC ; American type culture collection ; CD30 ; cluster of differentiation 30 a type I transmembrane glycoprotein belonging to the TNF receptor superfamily ; CD31 ; platelet endothelial cell adhesion molecule 1 ; EGF ; epidermal growth factor ; EPHB4 ; ephrin type-B receptor 4 ; ERK ; extracellular signal-regulated kinase ; FGFR ; fibroblast growth factor receptor ; FLT3 ; fms-related tyrosine kinase 3 ; JAK2 ; janus kinase 2 ; L858R ; leucine 858 mutated to arginine ; L861Q ; leucine 861 mutated to glutamine ; M ; m

刊名：Biochemical Pharmacology

出版年：2017

6.Cellular and molecular mechanisms underlying alcohol-induced aggressiveness of breast cancer

作者：Yongchao Wang^a ; Mei Xu^a ; Zun-ji Ke^b ; Jia Luo^a ; ^b ; ^{jialuo888@uky.edu}

关键词：ADH ; alcohol dehydrogenase ; ALDH2 ; aldehyde dehydrogenase ; C3G ; cyanidin-3-glucoside ; CCL2 ; chemokine (CC motif) ligand 2 ; CCR2 ; chemokine (CC motif) receptor 2 ; CSC ; cancer stem cells ; CYP2E1 ; cytochrome P450 2E1 ; ECM ; extracellular matrix ; EGFR ; epidermal growth factor receptor ; EMT ; epithelial-mesenchymal transition ; MCP-1 ; monocyte chemoattractant protein 1 ; MMPs ; matrix metalloproteinases ; NOX ; NADPH oxidase ; ROS ; reactive oxygen species ; VEGF ; vascular endothelial growth factor

刊名：Pharmacological Research

出版年：2017

7.A Highly Diverse and Functional Naïve Ubiquitin Variant Library for Generation of Intracellular Affinity Reagents

作者：Isabel Leung¹ ; ² ; Nick Jarvik² ; Sachdev S. Sidhu¹ ; ² ; ^{sachdev.sidhu@utoronto.ca}

关键词：Ubv ; ubiquitin variant ; Ub ; ubiquitin ; wt ; wild-type ; EGFR ; epidermal growth factor receptor ; EGF ; epidermal growth factor ; Her3 ; human epidermal growth factor receptor 3 ; NRG ; neuregulin ; Grb2 ; growth factor receptor-bound protein 2 ; GST ; glutathione S-transferase ; SPR ; surface plasmon resonance ; IP ; immunoprecipitation ; Grb2-SH2 ; Grb2 SH2 domain ; p-Tyr ; phospho-tyrosine ; pERK ; phosphorylated ERK ; pMEK ; phosphorylated MEK ; ERK ; extracellular signal-regulated kinase ; MEK ; MAPK/ERK kinase

刊名：Journal of Molecular Biology

出版年：2017

8.Senescence as biologic endpoint following pharmacological targeting of receptor tyrosine kinases in cancer

作者：Paola Francica ; Daniel M. Aebersold ; Michaela Medová ; ; ^{michaela.medova@dkf.unibe.ch}

关键词：ATIR ; anti-tumor immune response ; ATM ; ataxia telangiectasia mutated ; CDK ; cyclin-dependent kinase ; CGH ; comparative genomic hybridization ; CHK1 ; checkpoint kinase 1 ; CHK2 ; checkpoint kinase 2 ; DDAs ; DNA-damaging agents ; DDR ; DNA damage response ; DSBs ; double-strand breaks ; EGF ; epidermal growth factor ; EGFR ; epidermal growth factor receptor ; EPHA3 ; EPH Receptor A3 ; FGFR ; fibroblast growth factor receptor ; FOXM1 ; Forkhead box protein M1 ; GAS6 ; growth arrest-specific protein 6 ; H3K9me3 ; histone 3

刊名：Biochemical Pharmacology

出版年：2017

9.Shikonin inhibits gefitinib-resistant non-small cell lung cancer by inhibiting TrxR and activating the EGFR proteasomal degradation pathway

作者：Xia Li¹ ; Xing-Xing Fan¹ ; Ze-Bo Jiang ; Wings TY Loo ; Xiao-Jun Yao ; Elaine Lai-Han Leung ; ^{lhleung@must.edu.mo} ; Louis WC Chow ; ^{wcchow@must.edu.mo} ; Liang Liu ; ^{lliu@must.edu.mo}

关键词：NSCLC ; non-small cell lung cancer cell ; ROS ; reactive oxygen species ; EGFR ; epidermal growth factor receptor ; T790M ; a substitution mutation of threonine with methionine at position 790 of EGFR ; TrxR ; thioredoxin reductases ; MTT ; 3-(4 ; 5-dimetrylthiazol)-2 ; 5-diphenyltetrazolium bromide ; DCFDA ; dichlorofluorescein diacetate ; PBS ; phosphate-buffered saline ; RIPA ; radioimmunoprecipitation assay ; PARP ; poly (ADP-ribosyl) polymerase ; NAC ; N-acetyl-l-cysteine ; MG132 ; proteasomal degradation pathway inh

刊名：Pharmacological Research

出版年：2017

10.Intercalated Chemotherapy and Epidermal Growth Factor Receptor Inhibitors for Patients With Advanced Non-Small-cell Lung Cancer: A Systematic Review and Meta-analysis

作者：Anna La Salvia¹ ; Antonio Rossi² ; ^{arossi_it@yahoo.it} ; Domenico Galetta³ ; Elisa Gobbini¹ ; Emmanuele De Luca¹ ; Silvia Novello¹ ; Massimo Di Maio¹

关键词：Afatinib ; Erlotinib ; Gefitinib ; Mutation ; NSCLC

刊名：Clinical Lung Cancer

出版年：2017

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