作者：Kang-Yeoun Jung^a ; ^d ; Jihyun Park^b ; ^d ; Young-Sung Han^a ; Young Han Lee^c ; Soon Young Shin^c ; ^{shinsy@konkuk.ac.kr} ; Yoongho Lim^b ; ^{yoongho@konkuk.ac.kr}

关键词：GI50 ; half-maximal cell growth inhibitory concentration

刊名：Bioorganic & Medicinal Chemistry

出版年：2017

作者：Yingshan Luo^a ; Lihua Tong^a ; Hui Meng^a ; Weiliang Zhu^a ; Linlang Guo^b ; Ting Wei^a ; ^{258077534@qq.com} ; Jian Zhang^a ; ^{blacktiger@139.com}

关键词：SCLC ; small cell lung cancer ; PARP-1 ; Poly [ADP-ribose] polymerase 1 ; miRNAs ; microRNAs ; ccRcc ; clear cell renal cell carcinoma ; NAD + ;   ; nicotinamide adenine dinucleotide ; qRT-PCR ; quantitative real-time PCR ; GAPDH ; glyceraldehyde-3-phosphate dehydrogenase ; DDP ; cisplatin ; VP-16 ; etoposide ; ADM ; Adriamycin ; CCK-8 ; Cell Counting Kit-8 ; IC50 ; the half maximal inhibitory concentration of a substance

刊名：Gene

出版年：2017

作者：Valeria V. Costantino^a ; Lorena Lobos-Gonzalez^b ; Jorge Ibañ ; ez^a ; Dario Fernandez^a ; F. Darí ; o Cuello-Carrió ; n^c ; Manuel A. Valenzuela^b ; Manuel A. Barbieri^d ; Silvana N. Semino^a ; Graciela A. Jahn^c ; Andrew F.G. Quest^b ; ^{aquest@med.uchile.cl" class="auth_mail" title="E-mail the corresponding author} ; Luis A. Lopez^a ; ^{llopez@fcm.uncu.edu.ar" class="auth_mail" title="E-mail the corresponding author}

关键词：FBS ; fetal bovine serum ; HE ; hematoxylin-eosin ; SA- β -Gal ; senescence-associated β-galactosidase ; IC50 ; half maximal inhibitory concentration ; gv ; tumor growth velocity ; DDR ; DNA damage response

刊名：Cancer Letters

出版年：2016

作者：Hirofumi Sakoguchi^a ; Akihide Yoshihara^b ; Tomoya Shintani^c ; Kazuhiro Okuma^c ; Ken Izumori^b ; Masashi Sato^a ; ^{sato@ag.kagawa-u.ac.jp" class="auth_mail" title="E-mail the corresponding author}

关键词：IC50 ; half maximal inhibitory concentration ; SD ; standard deviation ; ATP ; adenosine triphosphate ; NAD ; nicotinamide adenine dinucleotide ; NADP ; nicotinamide adenine dinucleotide phosphate

刊名：Bioorganic & Medicinal Chemistry Letters

出版年：2016

作者：Vahid Heravi Shargh^a ; ^b ; ^{Vahid.HeraviShargh@uon.edu.au} ; Hubert Hondermarck^a ; ^b ; ^{Hubert.Hondermarck@newcastle.edu.au} ; Mingtao Liang^a ; ^b ; ^{roger.liang@newcastle.edu.au}

关键词：BCA ; bicinchoninic acid ; BSA ; bovine serum albumin ; CS ; chitosan ; DLS ; dynamic light scattering ; DMSO ; dimethyl sulfoxide ; DS ; dextran sulfate ; EPR ; enhanced permeability and retention ; FBS ; fetal bovine serum ; gp ; glycoprotein ; HPLC ; high-performance liquid chromatography ; IC50 ; half-maximal inhibitory concentration ; IgM ; immunoglobulin M ; MAPK ; mitogen-activated protein kinase ; MW ; molecular weight ; Nab&trade ; nanoparticle albumin-bound technology ; NGF ; nerve growth factor ; NP ; nanoparticle

刊名：International Journal of Pharmaceutics

出版年：2016

作者：Andrea Derksen^a ; Joachim Kü ; hn^b ; Wali Hafezi^b ; Jandirk Sendker^a ; Christina Ehrhardt^c ; Stephan Ludwig^c ; Andreas Hensel^a ; ^{ahensel@uni-muenster.de" class="auth_mail" title="E-mail the corresponding author}

关键词：EGF ; epidermal growth factor ; EtOH ; ethanol ; HA ; hemagglutinin ; HU ; hemagglutinating units ; IAV ; influenza A virus ; MIC ; minimum inhibitory concentration ; pfu ; plaque forming units ; PVP ; polyvinylpyrrolidone ; TNF ; tumor necrosis factor ; UHPLC-MS ; ultra high pressure liquid chromatography coupled to mass spectrometric detection

刊名：Journal of Ethnopharmacology

出版年：2016

作者：Na-Reum Ha^a ; Sang-Choon Lee^a ; Jae-Wook Hyun^b ; Moon-Young Yoon^a ; ^{myyoon@hanyang.ac.kr" class="auth_mail" title="E-mail the corresponding author}

关键词：FtsZ ; filamenting temperature sensitive mutantZ ; X. axonopodis ; Xanthomonas axonopodis pv. citri ; SELEX ; systematic evolution of ligands by exponential enrichment ; IC50 ; half maximal inhibitory concentration ; MIC50 ; half minimum inhibitory concentration

刊名：Process Biochemistry

出版年：2016

作者：Senem Aykul ; Erik Martinez-Hackert ; ^{emh@msu.edu" class="auth_mail" title="E-mail the corresponding author}

关键词：Cerberus ; BMP-4 ; Surface plasmon resonance ; SPR ; TGF-β ; Bone morphogenetic protein ; IC50 ; Inhibitor

刊名：Analytical Biochemistry

出版年：2016

作者：Radoslaw Laufer ; ^{Radek.Laufer@oicr.on.ca" class="auth_mail" title="E-mail the corresponding author} ; Sze-Wan Li ; Yong Liu ; Grace Ng ; Yunhui Lang ; Miklos Feher ; Richard Brokx ; Irina Beletskaya ; Richard Hodgson ; Guodong Mao ; Olga Plotnikova ; Donald E. Awrey ; Jacqueline M. Mason ; Xin Wei ; Dan Chi-Chia Lin ; Yi Che ; Reza Kiarash ; Brian Madeira ; Graham C. Fletcher ; Tak W. Mak ; Mark R. Bray ; Henry W. Pauls

关键词：Ar ; aryl ; ATP ; Adenosine-5&prime ; -triphosphate ; AUC ; area under the curve ; BA ; bioavailability ; CYP ; Cytochrome P450 ; DBU ; 1 ; 8-diazabicyclo[5.4.0]undec-7-ene ; DCM ; dichloromethane ; DIPEA ; diisopropylethylamine ; Δ ; heat ; DME ; 1 ; 2-dimethoxyethane ; DMF ; N ; N-dimethylformamide ; DMSO ; dimethyl sulfoxide ; dppf ; 1 ; 1&prime ; -bis(diphenylphosphino)ferrocene ; h ; hour or human (in MS) ; GI50 ; half maximal cell growth inhibitory concentration ; Hb ; hydrophobe ; IC50 ; half maximal inhibitory concentration ; m ; mou

刊名：Bioorganic & Medicinal Chemistry Letters

出版年：2016

作者：Xian-Hai Lv^a ; ^b ; Zi-Li Ren^b ; Ben-Guo Zhou^b ; Qing-Shan Li^c ; Ming-Jie Chu^a ; Dao-Hong Liu^a ; Kai Mo^a ; Li-Song Zhang^a ; Xiao-Kang Yao^a ; Hai-Qun Cao^b ; ^{haiquncao@163.com" class="auth_mail" title="E-mail the corresponding author}

关键词：MEK ; mitogen-activated protein kinase ; BRAF ; V-RAF murine sarcoma viral oncogene homologue B1 ; ERK ; extracellular regulated kinase ; BRAFV600E ; V600E mutant BRAF ; BRAFV600K ; V600K mutant BRAF ; IC50 ; half maximal inhibitory concentration ; GI50 ; the concentration that causes 50% growth inhibition ; SAR ; structure&ndash ; activity relationship

刊名：Bioorganic & Medicinal Chemistry

出版年：2016