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Elsevier电子期刊(28)

在“Elsevier电子期刊”中，命中：28条，耗时：0.0689681 秒

在所有数据库中总计命中：33条

1.Alamethicin for using in bioavailability studies? - Re-evaluation of its effect

作者：Maren Vollmer ^{Maren.Vollmer@chemie.uni-hamburg.de} ; Mirko Klingebiel ^{mikl1710@kdwelt.de} ; Sascha Rohn ; ^{rohn@chemie.uni-hamburg.de} ; Ronald Maul ^{maul@chemie.uni-hamburg.de}

关键词：Clint ; intrinsic clearance ; Clint app. ; apparent intrinsic clearance ; DAD ; diod array detector ; DMSO ; dimethyl sulfoxide ; ER ; endoplasmic reticulum ; fu ; unbound fraction of a drug in the microsomal incubation mixture ; HPLC ; high performance liquid chromatography ; Km ; Michaelis-Menten constant ; P ; partition coefficient ; S ; substrate concentration ; UDP ; uridine diphosphate ; UDPGA ; uridine 5&prime ; -diphosphoglucuronic acid trisodium salt ; UGT ; UDP-glucuronosyltransferase ; v ; velocity ; Vmax ; maximal

刊名：Toxicology in Vitro

出版年：2017

2.Cremophor EL-based nanoemulsion enhances transcellular permeation of emodin through glucuronidation reduction in UGT1A1-overexpressing MDCKII cells

作者：Tianpeng Zhang^a ; ¹ ; Dong Dong^b ; ¹ ; Danyi Lu^a ; Shuai Wang^a ; Baojian Wu^a ; ^{bj.wu@hotmail.com" class="auth_mail" title="E-mail the corresponding author}

关键词：DMEM ; Dulbecco&rsquo ; s modified Eagle&rsquo ; s medium ; FBS ; fetal bovine serum ; SDS ; sodium dodecyl sulfonate ; MCT ; medium chain triglycerides ; MDCK1A1 cells ; UGT1A1-overexpressing MDCKII cells ; UDPGA ; uridine diphosphoglucuronic acid ; UGT ; UDP-glucuronosyltransferase ; EMO-NE ; emodin nanoemulsion ; TEM ; transmission electron microscopy ; EMO ; emodin ; EMO-G ; emodin glucuronide ; UPLC ; ultra performance liquid chromatography

刊名：International Journal of Pharmaceutics

出版年：2016

3.Renal glucuronidation and multidrug resistance protein 2-/ multidrug resistance protein 4-mediated efflux of mycophenolic acid: interaction with cyclosporine and tacrolimus

作者：Azza A.K. El-Sheikh^a ; Jan B. Koenderink^b ; Alfons C. Wouterse^b ; Petra H.H. van den Broek^b ; Vivienne G.M. Verweij^b ; Rosalinde Masereeuw^b ; Frans G.M. Russel^b ; ^{Frans.Russel@radboudumc.nl" class="auth_mail}

关键词：CsA ; cyclosporine A ; FVB ; friend leukemia virus B strain ; HEK293 ; human embryonic kidney 293 ; HPLC ; high-performance liquid chromatography ; MMF ; mycophenolate mofetil ; MPA ; mycophenolic acid ; MPAG ; 7-hydroxy mycophenolic acid glucuronide ; MRP ; multidrug resistance protein ; MTT ; 3-[4 ; 5-dimethylthiazol-2-yl]-2 ; 5-diphenyltetrazolium bromide ; OAT ; organic anion transporter ; Tac ; tacrolimus ; UDPGA ; uridine 5&prime ; -diphosphoglucuronic acid ; UGT ; uridine diphosphoglucuronosyltransferase ; WH ; Wistar Ha

刊名：Translational Research

出版年：July 2014

4.Glucuronidation of estrone and 16α-hydroxyestrone by human UGT enzymes: The key roles of UGT1A10 and UGT2B7

作者：Roope A. Kallionpä ; ä ; ¹ ; Erkka Jä ; rvinen ; Moshe Finel ; ^{moshe.finel@helsinki.fi" class="auth_mail" title="E-mail the corresponding author}

关键词：16α-OHE1 ; 16α-hydroxyestrone ; E1 ; estrone ; E2 ; 17β-estradiol ; HIM ; human intestine microsomes ; HLM ; human liver microsomes ; UDPGA ; uridine 5&prime ; -diphosphoglucuronic acid ; UGT ; UDP-glucuronosyltransferase

刊名：Journal of Steroid Biochemistry and Molecular Biology

出版年：2015

5.Efflux transport of chrysin and apigenin sulfates in HEK293 cells overexpressing SULT1A3: The role of multidrug resistance-associated protein 4 (MRP4/ABCC4)

作者：Wan Li¹ ; Hua Sun¹ ; Xingwang Zhang ; Huan Wang ; Baojian Wu ; ^{bj.wu@hotmail.com" class="auth_mail" title="E-mail the corresponding author}

关键词：AS ; apigenin sulfate ; BCRP/Bcrp ; breast cancer resistance protein ; CYP ; cytochrome P450 ; CS ; chrysin sulfate ; DMEM ; Dulbecco&rsquo ; s modified Eagle&rsquo ; s medium ; FBS ; fetal bovine serum ; Km ; Michaelis&ndash ; Menten constant ; MRP/Mrp ; multidrug resistance-associated protein ; MS ; mass spectroscopy ; shRNA ; short hairpin RNA ; UDPGA ; uridine diphosphoglucuronic acid ; SULT ; sulfotransferases ; UPLC ; ultra performance liquid chromatography ; Vmax ; maximal velocity

刊名：Biochemical Pharmacology

出版年：2015

6.Simultaneous determination of bilirubin and its glucuronides in liver microsomes and recombinant UGT1A1 enzyme incubation systems by HPLC method and its application to bilirubin glucuronidation studies

作者：Guo Ma¹ ; ^{mg0328@126.com" class="auth_mail} ; ^{mg0328@fudan.edu.cn" class="auth_mail} ; Jiayuan Lin¹ ; Weimin Cai ; Bo Tan ; Xiaoqiang Xiang ; Ying Zhang ; Peng Zhang ; ^{zhampm@126.com" class="auth_mail}

关键词：UCB ; unconjugated bilirubin ; CB ; conjugated bilirubin ; BG ; bilirubin glucuronides ; BMGs ; bilirubin monoglucuronides ; BDG ; bilirubin diglucuronide ; TBG ; total bilirubin glucuronides ; UGT(s) ; UDP-glucuronosyltransferase(s) ; UGT1A1 ; UDP-glucuronosyltransferases1A1 ; RLM ; rat liver microsomes ; HLM ; human liver microsomes ; UDPGA ; uridine diphosphoglucuronic acid ; DMSO ; dimethylsulfoxide ; MRP2 ; multidrug resistance-associated protein 2 ; HPLC ; high performance liquid chromatography ; QC ; quality control

刊名：Journal of Pharmaceutical and Biomedical Analysis

出版年：15 April, 2014

7.Metabolism studies of ifenprodil, a potent GluN2B receptor antagonist

作者：Evamaria Falck ; Frank Begrow ; Eugen Verspohl ; Bernhard W眉nsch

关键词：BSA ; bovine serum albumin ; CNS ; central nervous system ; COMT ; catechol-O-methyl transferase ; EIC ; extracted ion current ; NADPH ; nicotinamide adenine dinucleotide phosphate ; NMDA ; N-methyl-d-aspartate ; PAPS ; adenosine-3&prime ; -phosphate-5&prime ; -phosphosulfate lithium salt hydrate ; SAM ; S-(5&prime ; -adenosyl)-l-methionine iodide ; TIC ; total ion current ; UDPGA ; uridine 5&prime ; -diphosphoglucuronic acid trisodium salt

刊名：Journal of Pharmaceutical and Biomedical Analysis

出版年：25 January, 2014

8.In vitro and in vivo biotransformation of WMS-1410, a potent GluN2B selective NMDA receptor antagonist

作者：Evamaria Falck ; Frank Begrow ; Eugen J. Verspohl ; Bernhard Wü ; nsch ; ^{wuensch@uni-muenster.de" class="auth_mail}

关键词：BSA ; bovine serum albumin ; CNS ; central nervous system ; COMT ; catechol-O-methyl transferase ; EIC ; extracted ion current ; IS ; internal standard ; NADPH ; nicotinamide adenine dinucleotide phosphate ; NMDA ; N-methyl-d-aspartate ; PAPS ; adenosine 3&prime ; -phosphate 5&prime ; -phosphosulfate lithium salt hydrate ; SAM ; S-(5&prime ; -adenosyl)-l-methionine iodide ; TIC ; total ion current ; UDPGA ; uridine 5&prime ; -diphosphoglucuronic acid trisodium salt

刊名：Journal of Pharmaceutical and Biomedical Analysis

出版年：June, 2014

9.Herb-drug interaction prediction based on the high specific inhibition of andrographolide derivatives towards UDP-glucuronosyltransferase (UGT) 2B7

作者：Hai-Ying Ma^a ; ¹ ; ^{cmu4h-mhy@126.com" class="auth_mail} ; Dong-Xue Sun^b ; ¹ ; Yun-Feng Cao^c ; ^d ; Chun-Zhi Ai^d ; Yan-Qing Qu^e ; Cui-Min Hu^d ; ^g ; Changtao Jiang^f ; Pei-Pei Dong^h ; Xiao-Yu Sun^d ; Mo Hong^d ; Naoki Tanaka^f ; Frank J. Gonzalez^f ; Xiao-Chi Ma^c ; ^d ; ^h ; ⁱ ; ^{maxc1978@163.com" class="auth_mail} ; Zhong-Ze Fang^c ; ^d ; ^f ; ^{zzfang228@gmail.com" class="auth_mail}

关键词：CYP ; cytochrome P450 ; DDI ; drug&ndash ; drug interaction ; HDI ; herb&ndash ; drug interaction ; HLMs ; human liver microsomes ; 4-MU ; 4-methylumbelliferone ; 4-MUG ; 4-methylumbelliferone-尾-d-glucuronide ; TFP ; trifluoperazine ; UGTs ; UDP-glucuronosyltransferases ; UDPGA ; uridine-5&prime ; -diphosphoglucuronic acid

刊名：Toxicology and Applied Pharmacology

出版年：15 May, 2014

10.Mass spectrometric characterization of glucuronides formed by a new concept, combining Cunninghamella elegans with TEMPO

作者：Axel Rydevik ; Ulf Bondesson ; Mario Thevis ; Mikael Hedel

关键词：TEMPO ; tetramethylpiperidinyl-1-oxy ; SARM ; selective androgen receptor modulator ; HRMS ; high resolution mass spectrometry ; UDPGA ; uridine 5&prime ; -diphosphoglucuronic acid ; NADPH ; nicotinamide adenine dinucleotide phosphate

刊名：Journal of Pharmaceutical and Biomedical Analysis

出版年：2013

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