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Elsevier电子期刊(140)

在“Elsevier电子期刊”中，命中：140条，耗时：小于0.01 秒

在所有数据库中总计命中：175条

1.Mast cell and eosinophil surface receptors as targets for anti-allergic therapy

作者：Roopesh Singh Gangwar¹ ; Nadine Landolina¹ ; Ludovica Arpinati ; Francesca Levi-Schaffer ; ^{francescal@ekmd.huji.ac.il}

关键词：Ab ; Antibody ; AEU ; Allergic Effector Unit ; AHR ; Airway Hyperresponsiveness ; ATP ; Adenosine 5&prime ; -triphosphate ; BMMC ; Bone Marrow derived Mast Cells ; CB ; Cannabinoid Receptor ; CBMC ; Cord Blood derived Mast Cells ; CCR3 ; C-C Chemokine Receptor type 3 ; COPD ; Chronic Obstructive Pulmonary Disease ; CRH ; Corticotropin-Releasing Hormone ; CRTH2 ; Chemokine Receptor homologous molecule expressed on T Helper type 2 ; CS ; Glucocorticosteroids ; ECP ; Eosinophil Cationic Protein ; EP2 ; 3 ; 4 ; E-Prostanoid 2 ; 3

刊名：Pharmacology & Therapeutics

出版年：2017

2.Patient stratification and the unmet need in asthma

作者：Linda Swedin¹ ; Tiiu Saarne¹ ; Maria Rehnberg ; Pernilla Glader ; Magdalena Niedzielska ; Gustav Johansson ; Petra Hazon ; Matthew C. Catley ; ^{matthew.catley@astrazeneca.com}

关键词：ACOS ; asthma and chronic obstructive pulmonary disease overlap syndrome ; ACQ ; Asthma Control Questionnaire ; AHR ; airway hyperresponsiveness ; ASM ; airway smooth muscle ; BAL ; bronchoalveolar lavage ; BHR ; bronchial hyperresponsiveness ; CLCA1 ; chloride channel ; calcium activated family member 1 ; COPD ; chronic obstructive pulmonary disease ; CRTh2 ; chemoattractant receptor-homologous molecule expressed on Th2 cells ; cysLTs ; cysteinyl leukotrienes ; DCs ; dendritic cells ; DPP-4 ; dipeptidyl peptidase-4 ; F

刊名：Pharmacology & Therapeutics

出版年：2017

3.Pharmacological characterization of CRTh2 antagonist LAS191859: Long receptor residence time translates into long-lasting in vivo efficacy

作者：Marta Calbet ; ^{marta.calbet@almirall.com" class="auth_mail" title="E-mail the corresponding author} ; Miriam Andrés ; Clara Armengol ; Mó ; nica Bravo ; Peter Eichhorn ; Rosa Ló ; pez ; Vicente Garcí ; a-Gonzá ; lez ; Richard Roberts ; Montserrat Miralpeix

关键词：cAMP ; cyclic adenosine monophosphate ; CHO ; chinese hamster ovary cell line ; CRTh2 ; chemoattractant receptor-homologous molecule expressed on T-helper cells ; DK-PGD2 ; 13-14-dihydro-15-keto-PGD2 ; GDP ; guanosine diphosphate ; GPCR ; G protein-coupled receptor ; GTP ; guanosine triphosphate ; PGD2 ; prostaglandin D2 ; PMN ; polymorphonuclear cells ; Th2 ; T-helper cells type 2

刊名：Pharmacological Research

出版年：2016

4.Prostaglandin D₂ signaling mediated by the CRTH2 receptor is involved in MK-801-induced cognitive dysfunction

作者：Yusuke Onaka^a ; ^b ; ¹ ; Norihito Shintani ; Ph.D.^a ; ¹ ; ^{shintani@phs.osaka-u.ac.jp" class="auth_mail" title="E-mail the corresponding author} ; Takanobu Nakazawa^a ; ^c ; ^d ; ¹ ; Takuya Kanoh^a ; ¹ ; Yukio Ago^a ; ^e ; Toshio Matsuda^e ; Ryota Hashimoto^f ; ^g ; Kazutaka Ohi^g ; Hiroyuki Hirai^h ; Kin-ya Nagata^h ; Masataka Nakamuraⁱ ; Atsushi Kasai^a ; Atsuko Hayata-Takano^a ; ^f ; Kazuki Nagayasu^a ; ^c ; Kazuhiro Takuma^d ; ^f ; Asao Ogawa^j ; Akemichi Baba^k ; Hitoshi Hashimoto ; Ph.D.^a ; ^c ; ^f ; ^l ; ^{hasimoto@phs.osaka-u.ac.jp" class="auth_mail" title="E-mail the corresponding author}

关键词：CRTH2 ; chemoattractant receptor homologous molecule expressed on T helper type 2 cells ; COX ; cyclooxygenase ; LPS ; lipopolysaccharide ; NMDA ; N-methyl-d-aspartate ; NORT ; novel object recognition test ; PVN ; paraventricular nucleus ; PC/RS ; posterior cingulate/retrosplenial cortex ; PG ; prostaglandin ; SNP ; single nucleotide polymorphism ; PFC ; prefrontal cortex

刊名：Behavioural Brain Research

出版年：2016

5.Structure-activity relationships (SAR) and structure-kinetic relationships (SKR) of sulphone-based CRTh2 antagonists

作者：Maria Antonia Buil^a ; Marta Calbet^a ; Marcos Castillo^b ; Jordi Castro^a ; Cristina Esteve^a ; Manel Ferrer^a ; Pilar Forns^b ; Jacob Gonzá ; lez^a ; Sara Ló ; pez^a ; Richard S. Roberts^a ; ¹ ; ^{rick.roberts@almirall.com" class="auth_mail" title="E-mail the corresponding author} ; Sara Sevilla^a ; Bernat Vidal^a ; Laura Vidal^a ; Pere Vilaseca^a

关键词：CRTh2 antagonist ; Receptor residence time ; Structure-activity relationship (SAR) ; Structure-kinetic relationship (SKR)

刊名：European Journal of Medicinal Chemistry

出版年：2016

6.Effect of prostaglandin D2 on VEGF release by nasal polyp fibroblasts

作者：Kengo Kanai^a ; ^b ; Mitsuhiro Okano^a ; ^{mokano@cc.okayama-u.ac.jp" class="auth_mail" title="E-mail the corresponding author} ; Tazuko Fujiwara^a ; Shin Kariya^a ; Takenori Haruna^a ; Ryotaro Omichi^a ; Sei-ichiro Makihara^c ; Yuji Hirata^b ; Kazunori Nishizaki^b

关键词：CRTH2 ; DP ; Nasal polyp fibroblast ; PGD2 ; VEGF

刊名：Allergology International

出版年：2016

7.Data on the oral CRTh2 antagonist QAW039 (fevipiprant) in patients with uncontrolled allergic asthma

作者：Veit J. Erpenbeck^a ; ^{veit.erpenbeck@novartis.com} ; Todor A. Popov^b ; David Miller^c ; Steven F. Weinstein^d ; Sheldon Spector^e ; Baldur Magnusson^a ; Wande Osuntokun^f ; Paul Goldsmith^f ; Markus Weiss^a ; Jutta Beier^g

刊名：Data in Brief

出版年：2016

8.The oral CRTh2 antagonist QAW039 (fevipiprant): A phase II study in uncontrolled allergic asthma

关键词：Asthma ; Chemoattractant receptor-homologous molecule expressed on Th2 cells ; Clinical trial

刊名：Pulmonary Pharmacology & Therapeutics

出版年：2016

9.Prostaglandin D₂ is a novel repressor of IFNγ induced indoleamine-2,3-dioxygenase via the DP1 receptor and cAMP pathway

作者：Nesrine Kamal Bassal ; Bernard P Hughes ; Maurizio Costabile ; ^{maurizio.costabile@unisa.edu.au" class="auth_mail" title="E-mail the corresponding author}

关键词：IDO ; Indoleamine 2 ; 3-dioxygenase ; Kyn ; Kynurenine ; IFNγ ; Interferon-γ ; PKA ; Protein kinase A ; DP1 ; Prostanoid DP receptor ; CRTH2 ; Chemoattractant receptor homologous molecule expressed on Th2 cells

刊名：Prostaglandins, Leukotrienes and Essential Fatty Acids

出版年：2016

10.Targeting mast cells: Uncovering prolific therapeutic role in myriad diseases

作者：Jatinder Singh¹ ; Ramanpreet Shah¹ ; Dhandeep Singh ; ^{ddd300@gmail.com" class="auth_mail" title="E-mail the corresponding author}

关键词：AP1 ; Activator protein 1 ; cAMP ; Cyclic adenosine monophoshate ; CXCR ; Cytokine receptors ; CRTH2 ; Chemoattractant receptor-homologous molecule expressed on Th2 cells ; DAMPs ; Damage-associated molecular pattern ; EtBr ; Ethidium Bromide ; IgE ; Immunoglobulin E ; IKK ; IκB kinase ; IRF3 ; Interferon regulatory factor 3 ; LAT ; linker for activation of T cells ; LYN ; Tyrosine-protein kinase ; MAP3Ks ; Mitogen-activated protein kinase kinase kinases ; NFκB ; Nuclear factor kappa B ; NTAL ; Non-T-cell activation linke

刊名：International Immunopharmacology

出版年：2016

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