搜索页_Pyrido[2

设为首页

收藏本站

网站地图 | English | 公务邮箱

远程访问

NSTL服务站

外文资源

SpringerLink电子期刊(209)

Elsevier电子期刊(435)

ACS电子期刊(118)

在“Elsevier电子期刊”中，命中：435条，耗时：小于0.01 秒

在所有数据库中总计命中：795条

1.A structure-guided optimization of pyrido[2,3-d]pyrimidin-7-ones as selective inhibitors of EGFR^L858R/T790M mutant with improved pharmacokinetic properties

作者：Lei Yu^a ; ^b ; Minhao Huang^a ; ^b ; Tianfeng Xu^a ; ^b ; Linjiang Tong^d ; Xiao-e Yan^e ; Zhang Zhang^a ; Yong Xu^a ; Caihong Yun^e ; Hua Xie^d ; ^{hxie@simm.ac.cn} ; Ke Ding^a ; ^c ; ^{ding_ke@gibh.ac.cn} ; Xiaoyun Lu^c ; ^{luxy2016@jnu.edu.cn}

关键词：EGFRT790M mutant ; Pyrido[2 ; 3-d]pyrimidin-7-ones ; Pharmacokinetic property ; NSCLC ; Irreversible inhibitor

刊名：European Journal of Medicinal Chemistry

出版年：2017

2.Design and synthesis of novel 7-aminosubstituted pyrido[2,3-b]pyrazines exhibiting anti-breast cancer activity

作者：Orestis Argyros^a ; ¹ ; ^{ore_argyros@yahoo.com} ; Nikolaos Lougiakis^b ; ¹ ; ^{nlougiak@pharm.uoa.gr} ; Eva Kouvari^a ; ^{eva_kouvari@yahoo.gr} ; Alexandra Papafotika^c ; ^d ; ^{apapafot@cc.uoi.gr} ; Catherine P. Raptopoulou^e ; ^{c.raptopoulou@inn.demokritos.gr} ; Vassilis Psycharis^e ; ^{v.psycharis@inn.demokritos.gr} ; Savvas Christoforidis^c ; ^d ; ^{schristo@uoi.gr} ; Nicole Pouli^b ; ^{pouli@pharm.uoa.gr} ; Panagiotis Marakos^b ; ^{marakos@pharm.uoa.gr} ; Constantin Tamvakopoulos^a ; ^{ctamvakop@bioacademy.gr}

关键词：Breast cancer ; Pyridopyrazine ; In vivo activity ; PI3K ; Met translational medicine ; Pharmacokinetic parameters

刊名：European Journal of Medicinal Chemistry

出版年：2017

3.Efficient synthesis of a novel series of indeno fused pyrido[2,3-d]pyrimidines using β-cyclodextrin-propyl sulfonic acid as an eco-friendly catalyst

作者：Prasanna Nithiya Sudhan^a ; Majid Ghashang^b ; Syed Sheik Mansoor^a ; ^{smansoors2000@yahoo.co.in}

关键词：Pyrido[2 ; 3-d]pyrimidine ; One-pot reaction ; β-cyclodextrin-propyl sulfonic acid ; 1 ; 3-indandione ; 6-amino uracil

刊名：Beni-Suef University Journal of Basic and Applied Sciences

出版年：2016

4.Design, synthesis and biological evaluation of pyrido[2,3-d]pyrimidin-7-(8H)-ones as HCV inhibitors

关键词：Hepatitis C ; HCV genotype 1b replicon ; Small molecule inhibitor ; Pyrido[2 ; 3-d]pyrimidin-7-(8H)-ones

刊名：European Journal of Medicinal Chemistry

出版年：2016

5.A diastereoselective synthesis of tetrahydro- and dihydro-pyrido[2,3-c]coumarin derivatives via a one-pot three-component Povarov reaction catalyzed by bismuth(III) chloride

作者：Ch. Gurumurthy^a ; ^d ; Narjis Fatima^a ; G. Narender Reddy^b ; C. Ganesh Kumar^b ; Gowravaram Sabitha^a ; ^{gowravaramsr@yahoo.com" class="auth_mail" title="E-mail the corresponding author} ; ^{sabitha@iict.res.in" class="auth_mail" title="E-mail the corresponding author} ; K.V.S. Ramakrishna^c

关键词：Diastereoselective ; Bismuth(III) chloride ; Pyrido[2 ; 3-c]coumarins ; DPPH radical scavenging ; Aza-Diels&ndash ; Alder

刊名：Bioorganic & Medicinal Chemistry Letters

出版年：2016

6.Design, synthesis, anti-tumor activity, and molecular modeling of quinazoline and pyrido[2,3-d]pyrimidine derivatives targeting epidermal growth factor receptor

作者：Ju Hou¹ ; Shanhe Wan¹ ; Guangfa Wang ; Tingting Zhang ; Zhonghuang Li ; Yuanxin Tian ; Yonghuan Yu ; Xiaoyun Wu ; ^{xywugz@163.com" class="auth_mail" title="E-mail the corresponding author} ; Jiajie Zhang ; ^{zhangjj@smu.edu.cn" class="auth_mail" title="E-mail the corresponding author}

关键词：EGFR inhibitor ; Quinazoline and pyrido[2 ; 3-d]pyrimidine derivatives ; Antitumor ; Molecular docking ; Molecular dynamics simulation

刊名：European Journal of Medicinal Chemistry

出版年：2016

7.Synthesis of novel triazole/isoxazole functionalized 7-(trifluoromethyl)pyrido[2,3-d]pyrimidine derivatives as promising anticancer and antibacterial agents

作者：R. Naresh Kumar^a ; ^d ; G. Jitender Dev^a ; ^d ; N. Ravikumar^a ; D. Krishna Swaroop^a ; ^d ; B. Debanjan^b ; G. Bharath^c ; B. Narsaiah^a ; ^d ; ^{narsaiah@iict.res.in" class="auth_mail" title="E-mail the corresponding author} ; S. Nishant Jain^b ; A. Gangagni Rao^c

关键词：Pyrido[2 ; 3-d]pyrimidine ; Triazole ; Isoxazole ; Anticancer ; 1 ; 3-Dipolar cycloaddition ; Sharpless conditions

刊名：Bioorganic & Medicinal Chemistry Letters

出版年：2016

8.Synthesis, structures, electrochemical studies and antioxidant activity of 5-aryl-4-oxo-3,4,5,8-tetrahydropyrido[2,3-d]pyrimidine-7-carboxylic acids

作者：Jairo Quiroga^a ; ^b ; ^{jairo.quiroga@correounivalle.edu.co" class="auth_mail" title="E-mail the corresponding author} ; Pablo E. Romo^a ; ^b ; Alejandro Ortiz^a ; ^b ; José ; Hipó ; lito Isaza^c ; Braulio Insuasty^a ; ^b ; Rodrigo Abonia^a ; ^b ; Manuel Nogueras^d ; Justo Cobo^d

关键词：Pyrido[2 ; 3-d]pyrimidines ; Arylidene derivatives of pyruvic acid ; 6-Aminopyrimidines ; Microwave and ultrasound irradiation ; Antioxidant properties

刊名：Journal of Molecular Structure

出版年：2016

9.A series of pyrido[2,3-b]pyrazin-3(4H)-one derivatives as aldose reductase inhibitors with antioxidant activity

作者：Zhongfei Han ; Xin Hao ; Bing Ma ; Changjin Zhu ; ^{zcj@bit.edu.cn" class="auth_mail" title="E-mail the corresponding author}

关键词：Aldose reductase inhibitor ; Antioxidant activity ; Pyrido[2 ; 3-b]pyrazin-3(4H)-one ; Structure-activity relationship

刊名：European Journal of Medicinal Chemistry

出版年：2016

10.Discovery and analgesic evaluation of 8-chloro-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione as a novel potent d-amino acid oxidase inhibitor

作者：Dongsheng Xie¹ ; Jun Lu¹ ; Jin Xie ; Junjun Cui ; Teng-Fei Li ; Yan-Chao Wang ; Yuan Chen ; Nian Gong ; Xin-Yan Li ; Lei Fu ; ^{leifu@sjtu.edu.cn" class="auth_mail" title="E-mail the corresponding author} ; Yong-Xiang Wang ; ^{yxwang@sjtu.edu.cn" class="auth_mail" title="E-mail the corresponding author}

关键词：D-amino acid oxidase ; DAAO inhibitors ; 5-Azaquinoxaline-2 ; 3-diones ; Analgesic effects ; 8-Chloro-1 ; 4-dihydropyrido[2 ; 3-b]pyrazine-2 ; 3-dione

刊名：European Journal of Medicinal Chemistry

出版年：2016

按检索点细分(435)

题名(218)

关键词(145)

文摘(367)

按出版年细分(435)

2027年及以后(13)

2017年(2)

2016年(23)

2015年(9)

2013年(15)

2012年(32)

2011年(30)

2010年(19)

2009年(29)

2008年(15)

2007年(22)

2006年(11)

2005年(16)

2004年(30)

2003年(23)

2002年(15)

2001年(15)

2000年(24)

2000年及以前(92)

地址：北京市海淀区学院路29号邮编：100083

电话：办公室：(+86 10)66554848；文献借阅、咨询服务、科技查新：66554700