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Wiley电子期刊(1)	NATURE电子期刊(2)	ACS电子期刊(22)
SpringerLink电子期刊(14)	Elsevier电子期刊(39)

在“Elsevier电子期刊”中，命中：39条，耗时：0.0339537 秒

在所有数据库中总计命中：78条

1.Novel S1P₁ receptor agonists - Part 4: Alkylaminomethyl substituted aryl head groups

作者：Cyrille Lescop ; ^{cyrille.lescop@actelion.com" class="auth_mail" title="E-mail the corresponding author} ; Claus Mü ; ller ; Boris Mathys ; Magdalena Birker ; Ruben de Kanter ; Christopher Kohl ; Patrick Hess ; Oliver Nayler ; Markus Rey ; Patrick Sieber ; Beat Steiner ; Thomas Weller ; Martin H. Bolli

关键词：S1P1 receptor agonist ; Immunomodulator ; Lymphocyte count ; Aminomethyl pyridine ; Aminomethyl benzene ; Aminomethyl thiophene ; Phototoxicity

刊名：European Journal of Medicinal Chemistry

出版年：2016

2.Novel S1P₁ receptor agonists - Part 5: From amino-to alkoxy-pyridines

作者：Martin H. Bolli ; ^{martin.bolli@actelion.com" class="auth_mail" title="E-mail the corresponding author} ; Cyrille Lescop ; Magdalena Birker ; Ruben de Kanter ; Patrick Hess ; Christopher Kohl ; Oliver Nayler ; Markus Rey ; Patrick Sieber ; Jö ; rg Velker ; Thomas Weller ; Beat Steiner

关键词：S1P1 receptor agonist ; Pyridine ; Lymphocyte count ; Immunomodulation ; In vitro phototoxicity ; Light extinction

刊名：European Journal of Medicinal Chemistry

出版年：2016

3.Late-stage optimization of a tercyclic class of S1P₃-sparing, S1P₁ receptor agonists

作者：Joshua C. Horan^a ; ^{joshua.horan@proteostasis.com" class="auth_mail" title="E-mail the corresponding author} ; Daniel Kuzmich^a ; Pingrong Liu^a ; Darren DiSalvo^a ; John Lord^a ; Can Mao^a ; Tamara D. Hopkins^a ; Hui Yu^a ; Christian Harcken^a ; Raj Betageri^a ; Melissa Hill-Drzewi^a ; Lori Patenaude^b ; Monica Patel^a ; Kimberly Fletcher^a ; Donna Terenzzio^a ; Brian Linehan^a ; Heather Xia^a ; Mita Patel^a ; Debbie Studwell^c ; Craig Miller^a ; Eugene Hickey^a ; Jeremy I. Levin^a ; Dustin Smith^a ; Raymond A. Kemper^c ; Louise K. Modis^b ; Lynne C. Bannen^d ; Diva S. Chan^d ; Morrison B. Mac^d ; Stephanie Ng^d ; Yong Wang^d ; Wei Xu^d ; René ; M. Lemieux^a

关键词：SFBFJQXHRYGKHV-INIZCTEOSA-N ; SDCQNJRPSLMFIT-SFHVURJKSA-N ; GMEODUAZQQLOFF-MRXNPFEDSA-N ; MUINZQQLLPFAQS-OAHLLOKOSA-N

刊名：Bioorganic & Medicinal Chemistry Letters

出版年：2016

4.New fluorinated agonists for targeting the sphingosin-1-phosphate receptor 1 (S1P₁)

作者：Rizwan S. Shaikh^a ; ^b ; ^&dagger ; ; Petra Keul^c ; ^&dagger ; ; Michael Schä ; fers^d ; ^e ; ^f ; Bodo Levkau^c ; Gü ; nter Haufe^a ; ^e ; ^f ;

关键词：Fluorine ; FTY720 analogues ; G protein-coupled receptors ; Sphingosine-1-phosphate (S1P) ; S1P1 receptor agonist

刊名：Bioorganic & Medicinal Chemistry Letters

出版年：2015

5.Regulation of endothelial nitric oxide synthase activation in endothelial cells by S1P₁ and S1P₃

作者：M. Tö ; lle ; ¹ ; ^{Markus.Toelle@charite.de" class="auth_mail" title="E-mail the corresponding author} ; L. Klö ; ckl¹ ; A. Wiedon ; W. Zidek ; M. van der Giet ; M. Schuchardt

关键词：Endothelial nitric oxide synthesis ; Nitric oxide ; Sphingosine 1-phosphate ; S1P receptor ; AUY954 ; FTY720P

刊名：Biochemical and Biophysical Research Communications

出版年：2016

6.Targeting sphingosine-1-phosphate signaling in lung diseases

作者：David L. Ebenezer^a ; Panfeng Fu^b ; Viswanathan Natarajan^a ; ^b ; ^c ; ^d ; ^{visnatar@uic.edu}

关键词：4-DP ; 4&prime ; -deoxypridoxine ; ABC transporter ; ATP-binding cassette transporter ; Akt ; protein kinase B ; ALF4 ; tetrafluoroaluminate ; ALI ; acute lung injury ; ARDS ; acute respiratory distress syndrome ; ASM ; acid sphingomyelinase ; BACE1 ; beta-site APP-cleaving enzyme ; BAL ; bronchoalveolar lavage ; BMDC ; bone marrow derived cells ; BPD ; broncho pulmonary dysplasia ; CDK-2 ; cyclin dependent kinase ; CF ; Cystic fibrosis ; CFTR ; Cystic fibrosis transmembrane conductance regulator ; CoA ; co enzyme A ; COPD ; ch

刊名：Pharmacology & Therapeutics

出版年：2016

7.Dysregulation of sphingosine 1 phosphate receptor-1 (S1P1) signaling and regulatory lymphocyte-dependent immunosuppression in a model of post-fingolimod MS rebound

作者：Leonardo Cavone^a ; ^b ; ^{leonardo.cavone@unifi.it" class="auth_mail" title="E-mail the corresponding author} ; Roberta Felici^b ; Andrea Lapucci^b ; Daniela Buonvicino^b ; Sara Pratesi^c ; ^d ; Mirko Muzzi^b ; Bahia Hakiki^e ; Laura Maggi^c ; ^d ; Benedetta Peruzzi^f ; Roberto Caporale^f ; Francesco Annunziato^c ; ^d ; Maria Pia Amato^e ; Alberto Chiarugi^a ; ^b

关键词：Fingolimod withdrawal ; MS rebound ; EAE ; Treg

刊名：Brain, Behavior, and Immunity

出版年：2015

8.Development of a selective S1P₁ receptor agonist, Syl930, as a potential therapeutic agent for autoimmune encephalitis

作者：Jing Jin¹ ; Jinping Hu¹ ; Wanqi Zhou ; Xiaojian Wang ; Qiong Xiao ; Nina Xue ; Dali Yin ; ^{yindali@imm.ac.cn" class="auth_mail} ; Xiaoguang Chen ; ^{chxg@imm.ac.cn" class="auth_mail}

关键词：S1P1 ; sphingosine-1-phosphate receptor subtype 1 ; S1P3 ; sphingosine-1-phosphate receptor subtype 3 ; S1P ; sphingosine 1-phosphate ; EAE ; experimental autoimmune ancephalomyelitis ; PBL ; periphery blood lymphocytes ; MS ; multiple sclerosis ; CNS ; central nervous system ; FDA ; U.S. food and drug administration ; SAR ; structure activity relationship ; CHO-K1 ; Chinese hamster ovary-K1 ; FBS ; fetal bovine serum ; HUVEC ; human umbilical vein endothelial cell ; ECGS ; endothelial cell growth supplement ; SD ; Spragu

刊名：Biochemical Pharmacology

出版年：1 July 2014

9.Isoforms of protein kinase C involved in phorbol ester-induced sphingosine 1-phosphate receptor 1 phosphorylation and desensitization

作者：Marco Antonio Morquecho-Le贸n ; Silvana Baz煤a-Valenti ; M. Teresa Romero-脕vila ; J. Adolfo Garc铆a-S谩inz

关键词：S1P1 ; sphingosine-1-phosphate receptor 1 ; S1P ; sphingosine-1-phosphate ; PKC ; protein kinase C ; GFP ; green fluorescent protein ; GRK ; G protein-coupled receptor kinase ; shRNA ; short hairpin RNA

刊名：Biochimica et Biophysica Acta (BBA)/Molecular Cell Research

出版年：February, 2014

10.Protection of ferrets from pulmonary injury due to H1N1 2009 influenza virus infection: Immunopathology tractable by sphingosine-1-phosphate 1 receptor agonist therapy

关键词：H1N1 influenza ; Ferrets ; S1P1 Rec agonist ; RP-002 ; Oseltamivir ; Pathogenesis

刊名：Virology

出版年：March, 2014

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