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Elsevier电子期刊(127)

在“Elsevier电子期刊”中，命中：127条，耗时：0.0479777 秒

在所有数据库中总计命中：157条

1.Phenotypic characterization of Grm1^crv4 mice reveals a functional role for the type 1 metabotropic glutamate receptor in bone mineralization

作者：Ilaria Musante^a ; ^{Ilaria.musante@unige.it} ; Deborah Mattinzoli^b ; ^c ; ^{deborah.mattinzoli@gmail.com} ; Lavinia Alexandra Otescu^d ; ^{lao1e13@soton.ac.uk} ; Simone Bossi^a ; ^{3041842@studenti.unige.it} ; Masami Ikehata^b ; ^c ; ^{masami.ikehata@gmail.com} ; Chiara Gentili^e ; ^{chiara.gentili@unige.it} ; Giuliana Cangemi^f ; ^{GiulianaCangemi@ospedale-gaslini.ge.it} ; Cinzia Gatti^f ; ^{cinzia.dy@gmail.com} ; Laura Emionite^g ; ^{laura.emionite@hsanmartino.it} ; Piergiorgio Messa^b ; ^c ; ^{pmessa@policlinico.mi.it} ; Roberto Ravazzolo^a ; ^h ; ^{rravazzo@unige.it} ; Maria Pia Rastaldi^b ; ^c ; ^{mariapia.rastaldi@policlinico.mi.it} ; Daniela Riccardi^d ; ^{Riccardi@cardiff.ac.uk} ; Aldamaria Puliti^a ; ^h ; ^{apuliti@unige.it}

关键词：mGlu1 receptor ; Grm1crv4 mouse ; Bone mineralization ; Skeletal defect ; Ataxia ; Osteoblasts

刊名：Bone

出版年：2017

2.N-Alkylpyrido[1‿2‿1,5]pyrazolo-[4,3-d]pyrimidin-4-amines: A new series of negative allosteric modulators of mGlu_1/5 with CNS exposure in rodents

作者：Andrew S. Felts^a ; ^b ; Alice L. Rodriguez^a ; ^b ; Ryan D. Morrison^a ; ^b ; Daryl F. Venable^a ; ^b ; Anna L. Blobaum^a ; ^b ; Frank W. Byers^a ; ^b ; J. Scott Daniels^a ; ^b ; Colleen M. Niswender^a ; ^b ; Carrie K. Jones^a ; ^b ; P. Jeffrey Conn^a ; ^b ; Craig W. Lindsley^a ; ^b ; ^c ; Kyle A. Emmitte^a ; ^b ; ^c ; ^{kyle.emmitte@unthsc.edu" class="auth_mail" title="E-mail the corresponding author}

关键词：Metabotropic glutamate receptor subtype 1 (mGlu1) ; Metabotropic glutamate receptor subtype 5 (mGlu5) ; Negative allosteric modulator (NAM) ; Central nervous system (CNS) ; G-protein coupled receptor (GPCR)

刊名：Bioorganic & Medicinal Chemistry Letters

出版年：2016

3.Re-exploration of the mGlu₁ PAM Ro 07-11401 scaffold: Discovery of analogs with improved CNS penetration despite steep SAR

作者：Pedro M. Garcia-Barrantes^a ; Hyekyung P. Cho^a ; ^b ; Tahj M. Starr^a ; Anna L. Blobaum^a ; Colleen M. Niswender^a ; ^b ; ^c ; P. Jeffrey Conn^a ; ^b ; ^c ; Craig W. Lindsley^a ; ^b ; ^d ; ^{craig.lindsley@vanderbilt.edu" class="auth_mail" title="E-mail the corresponding author}

关键词：mGlu1 ; Metabotropic glutamate receptor ; Positive allosteric modulator (PAM) ; Schizophrenia ; Structure&ndash ; Activity Relationship (SAR)

刊名：Bioorganic & Medicinal Chemistry Letters

出版年：2016

4.Lead optimization of the VU0486321 series of mGlu₁ PAMs. Part 2: SAR of alternative 3-methyl heterocycles and progress towards an in vivo tool

作者：Pedro M. Garcia-Barrantes^a ; Hyekyung P. Cho^a ; ^b ; Adam M. Metts^c ; Anna L. Blobaum^a ; Colleen M. Niswender^a ; ^b ; P. Jeffrey Conn^a ; ^b ; Craig W. Lindsley^a ; ^b ; ^c ; ^{craig.lindsley@vanderbilt.edu" class="auth_mail" title="E-mail the corresponding author}

关键词：mGlu1 ; Metabotropic glutamate receptor ; Positive allosteric modulator (PAM) ; Schizophrenia ; Structure&ndash ; Activity Relationship (SAR)

刊名：Bioorganic & Medicinal Chemistry Letters

出版年：2016

5.Lead optimization of the VU0486321 series of mGlu₁ PAMs. Part 3. Engineering plasma stability by discovery and optimization of isoindolinone analogs

作者：Pedro M. Garcia-Barrantes^a ; Hyekyung P. Cho^a ; ^b ; Anna L. Blobaum^a ; Colleen M. Niswender^a ; ^b ; P. Jeffrey Conn^a ; ^b ; Craig W. Lindsley^a ; ^b ; ^c ; ^{craig.lindsley@vanderbilt.edu" class="auth_mail" title="E-mail the corresponding author}

关键词：mGlu1 ; Metabotropic glutamate receptor ; Positive allosteric modulator (PAM) ; Schizophrenia ; Structure&ndash ; activity relationship (SAR)

刊名：Bioorganic & Medicinal Chemistry Letters

出版年：2016

6.Amygdalar activation of group I metabotropic glutamate receptors produces anti- and pro-conflict effects depending upon animal sex in a sexually dimorphic conditioned conflict-based anxiety model

作者：Marí ; a I. De Jesú ; s-Burgos^a ; Stephanie Gonzá ; lez-Garcí ; a^b ; Yanira Cruz-Santa^c ; Nivia L. Pé ; rez-Acevedo^d ; ^{nivia.perez@upr.edu" class="auth_mail" title="E-mail the corresponding author}

关键词：Vogel Conflict Test ; Group I metabotropic glutamate receptos ; Estradiol ; Basolateral amygdala ; Sex differences

刊名：Behavioural Brain Research

出版年：2016

7.Function of mGlu1 receptors in the modulation of nociceptive processing in the thalamus

作者：T.E. Salt ; ^{t.salt@ucl.ac.uk" class="auth_mail} ; H.E. Jones ; C.S. Copeland ; A.M. Sillito

关键词：Thalamus ; Cortico-thalamic ; Metabotropic glutamate receptors ; mGlu1 ; Pain ; Nociception

刊名：Neuropharmacology

出版年：April, 2014

8.Lead optimization of the VU0486321 series of mGlu₁ PAMs. Part 1: SAR of modifications to the central aryl core

关键词：mGlu1 ; Metabotropic glutamate receptor ; Positive allosteric modulator (PAM) ; Schizophrenia ; Structure&ndash ; activity relationship (SAR)

刊名：Bioorganic & Medicinal Chemistry Letters

出版年：2015

9.Metabotropic glutamate receptors regulate cortical gamma hyperactivities elicited by ketamine in rats

作者：Tetsuaki Hiyoshi ; ^{t-hiyoshi@so.taisho.co.jp" class="auth_mail} ; Hirohiko Hikichi ; Jun-ichi Karasawa ; Shigeyuki Chaki

关键词：EEG ; Gamma ; Oscillations ; Ketamine ; mGlu2/3 receptor agonist ; mGlu1 receptor antagonist

刊名：Neuroscience Letters

出版年：1 May, 2014

10.Activation of lateral hypothalamic mGlu1 and mGlu5 receptors elicits feeding in rats

作者：J.R. Charles^a ; ^{jchar008@ucr.edu" class="auth_mail} ; ^{jonathanr.charles@gmail.com" class="auth_mail} ; M.A. Duva^b ; G.J. Ramirez^a ; R.L. Lara^a ; C.R. Yang^c ; B.G. Stanley^a ; ^b

关键词：Glutamate ; Lateral hypothalamus ; Metabotropic glutamate receptor ; Feeding

刊名：Neuropharmacology

出版年：April, 2014

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