搜索页_+Drug+design

设为首页

收藏本站

网站地图 | English | 公务邮箱

读者指南

学术客户端

NSTL服务站

科技查新

常用资源

馆藏书目(2)	CNKI会议论文(192)	CNKI期刊论文0611(92)
Springer电子图书(68)	CNKI学位论文(42238)	知网期刊论文(458150)

在“Elsevier电子期刊”中，命中：24,086条，耗时：0.1938785 秒

在所有数据库中总计命中：500,742条

1.Quality by design (QbD) approach of pharmacogenomics in drug designing and formulation development for optimization of drug delivery systems

作者：Sumeet Gupta ; ^{sumeetgupta25@gmail.com} ; Vikas Jhawat

关键词：Pharmacogenomics ; Genetic polymorphism ; Genetic markers ; Drug development ; Drug designing ; Drug targets ; Bioinformatics ; Dosage form evaluation and quality by design

刊名：Journal of Controlled Release

出版年：2017

2.Quality by Design (QbD)-enabled development of aceclofenac loaded-nano structured lipid carriers (NLCs): An improved dermatokinetic profile for inflammatory disorder(s)

作者：Neeraj K. Garg^a ; ¹ ; Gajanand Sharma^a ; ¹ ; Bhupinder Singh^a ; ^b ; ^{bsbhoop@yahoo.com} ; Pradip Nirbhavane^a ; Rajeev K. Tyagi^c ; ^d ; Rahul Shukla^a ; O.P. Katare^a ; ^{katare@pu.ac.in}

关键词：NLCs ; Nanostructured lipid carriers ; SLNs ; Solid lipid nanoparticles ; CA ; Cetyl alcohol ; QbD ; Quality by Design ; FbD ; Formulation by Design ; CQA ; Critical Quality Attributes ; CMA ; Critical Material Attributes ; CFA ; Critical Formulation Attributes ; Opt ; Optimized ; ACE ; Aceclofenac ; NSAIDs ; Non steroidal antiinflammatory drugs ; TNF-α ; Tumour necrosis factor α ; GIT ; Gastrointestinal tract ; MKT ; -Marketed ; QTPP ; Quality Target Product Profile ; ME ; -Microemulsion ; PDE ; Percentage drug entrapment ; BBD

刊名：International Journal of Pharmaceutics

出版年：2017

3.In silico receptor-based drug design of X,Y-benzenesulfonamide derivatives as selective COX-2 inhibitors

作者：David J. Pé ; rez^a ; Orlando Sarabia^a ; Manuel Villanueva-Garcí ; a^b ; Kayim Pineda-Urbina^a ; Á ; ngel Ramos-Organillo^a ; Jorge Gonzalez-Gonzalez^a ; Zeferino Gó ; mez-Sandoval^a ; ^{zgomez@ucol.com} ; Rodrigo Said Razo-Herná ; ndez^a ; ^c ; ^{rrazo@ucol.mx}

关键词：QSAR ; Docking ; Cyclooxygenase ; Benzenesulfonamides ; Drug design ; Artificial neural networks

刊名：Comptes Rendus Chimie

出版年：2017

4.Application of quality by design in the current drug development

作者：Lan Zhang ; Shirui Mao ; ^{maoshirui@syphu.edu.cn}

关键词：Quality by design (QbD) ; Process analytical technology (PAT) ; Critical quality attributes (CQA) ; Design of experiment (DoE) ; Risk assessment ; Near infrared (NIR) spectroscopy

刊名：Asian Journal of Pharmaceutical Sciences

出版年：2017

5.Copper nanowire coated carbon fibers as efficient substrates for detecting designer drugs using SERS

作者：Vladimir Halouzka^a ; ^c ; ¹ ; Barbora Halouzkova^b ; ¹ ; David Jirovsky^a ; Dusan Hemzal^d ; Peter Ondra^c ; Eirini Siranidi^e ; Athanassios G. Kontos^e ; Polycarpos Falaras^e ; Jan Hrbac^b ;

关键词：Copper nanowire ; SERS ; Designer drugs ; SERS substrate ; Carbon fiber ; Electrodeposition

刊名：Talanta

出版年：2017

6.The flavivirus capsid protein: Structure, function and perspectives towards drug design

作者：Edson R.A. Oliveira^a ; ^{edsonrao@gmail.com} ; Ronaldo Mohana-Borges^b ; Ricardo B. de Alencastro^a ; Bruno A.C. Horta^a

关键词：Flavivirus ; Capsid protein ; Drug design ; Antiviral ; Review

刊名：Virus Research

出版年：2017

7.Development of nanostructured lipid carriers containing salicyclic acid for dermal use based on the Quality by Design method

作者：A. Ková ; cs ; ^{anita.kovacs@pharm.u-szeged.hu} ; Sz. Berkó ; ^{berko@pharm.u-szeged.hu} ; E. Csá ; nyi ^{csanyi@pharm.u-szeged.hu} ; I. Csó ; ka ^{csoka@pharm.u-szeged.hu}

关键词：API ; active pharmaceutical ingredient ; CMAs ; critical material attributes ; CCS ; critical control strategy ; CPPs ; critical process parameters ; CQAs ; critical quality attributes ; DoE ; design of experiments ; DS ; design space ; ICH ; International Council for Harmonisation ; LD ; laser diffraction ; MP-SA ; micro-sized lipid particle containing salicyclic acid ; NLC SA ; nanostructured lipid carriers containing salicyclic acid ; NSAID ; non-steroidal anti-inflammatory drug ; PAT ; process analytical technology

刊名：European Journal of Pharmaceutical Sciences

出版年：2017

8.New approach of delivering cytotoxic drugs towards CAIX expressing cells: A concept of dual-target drugs

作者：Simon J.A. van Kuijk^a ; ¹ ; ^{s.vankuijk@maastrichtuniversity.nl} ; Nanda Kumar Parvathaneni^a ; ^b ; ¹ ; ^{nanda-kumar.parvathaneni@etu.umontpellier.fr} ; Raymon Niemans^a ; ¹ ; Marike W. van Gisbergen^a ; ¹ ; Fabrizio Carta^c ; Daniela Vullo^d ; Silvia Pastorekova^e ; Ala Yaromina^a ; Claudiu T. Supuran^c ; Ludwig J. Dubois^a ; ² ; Jean-Yves Winum^b ; ² ; Philippe Lambin^a ; ²

关键词：Tumor ; Hypoxia ; Carbonic anhydrase IX ; Dual-target drugs ; CAIX inhibitors ; Cytotoxic drugs

刊名：European Journal of Medicinal Chemistry

出版年：2017

9.Balancing Inflammation: Computational Design of Small-Molecule Toll-like Receptor Modulators

作者：Manuela S. Murgueitio¹ ; Christin Rakers¹ ; Anne Frank¹ ; Gerhard Wolber¹ ; ^{gerhard.wolber@fu-berlin.de}

关键词：Toll-like receptor ; virtual screening ; drug design ; inflammation

刊名：Trends in Pharmacological Sciences

出版年：2017

10.Development and evaluation of accelerated drug release testing methods for a matrix-type intravaginal ring

作者：Anna Externbrink^a ; Karin Eggenreich^b ; Simone Eder^b ; Stefan Mohr^b ; Klaus Nickisch^c ; Sandra Klein^a ; ^{sandra.klein@uni-greifswald.de}

关键词：Vaginal drug delivery ; Drug release kinetics ; Diffusion controlled drug release ; Accelerated drug release methods ; Temperature-controlled drug release ; Hydro-organic dissolution media

刊名：European Journal of Pharmaceutics and Biopharmaceutics

出版年：2017

按检索点细分(24086)

题名(1219)

关键词(1403)

文摘(20074)

常见问题　|　交通位置　|　联系我们　|　OA远程办公

地址：北京市海淀区学院路29号邮编：100083

电话：办公室：(+86 10)66554848；文献借阅、咨询服务、科技查新：66554700