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在“Elsevier电子期刊”中，命中：55条，耗时：0.0109896 秒

1.Much more than you expected: The non-DHFR-mediated effects of methotrexate

作者：Martin Sramek ; Jakub Neradil ; Renata Veselska ; ^{veselska@sci.muni.cz}

关键词：ADA ; adenosine deaminase ; AICAR ; 5-aminoimidazole-4-carboxamide ribonucleotide ; ALL ; acute lymphoblastic leukemia ; ATIC ; AICAR transformylase ; ATRA ; all-trans retinoic acid ; DHF ; dihydrofolate ; DHFR ; dihydrofolate reductase ; E2F1 ; E2F transcription factor 1 ; FAICAR ; 5-formaminoimidazole-4-carboxamide ribonucleotide ; FGAR ; formylglycinamide ribonucleotide ; FPGS ; folylpolyglutamate synthetase ; GAR ; glycinamide ribonucleotide ; GART ; GAR transformylase ; Glo1 ; glyoxalase I ; HATs ; histone acetyltransf

刊名：Biochimica et Biophysica Acta (BBA) - General Subjects

出版年：2017

2.The role of miR-190a in methylglyoxal-induced insulin resistance in endothelial cells

作者：Paola Mirra^a ; ^b ; ¹ ; Cecilia Nigro^a ; ^b ; ¹ ; Immacolata Prevenzano^a ; ^b ; Teresa Procopio^a ; ^b ; Alessia Leone^a ; ^b ; Gregory Alexander Raciti^a ; ^b ; Francesco Andreozzi^c ; Michele Longo^a ; ^b ; Francesca Fiory^a ; ^b ; Francesco Beguinot^a ; ^b ; Claudia Miele^a ; ^b ; ^{c.miele@ieos.cnr.it}

关键词：AG ; aminoguanidine ; AGE ; advanced glycation end-product ; Akt ; protein kinase B ; eNOS ; endothelial NO synthase ; ERK ; extracellular signal-regulated protein kinase ; Glo1 ; glyoxalase 1 ; HDAC ; histone deacetylase ; HUVECs ; human umbilical vein endothelial cells ; IRS-1 ; insulin receptor substrate 1 ; KRAS ; kirsten rat sarcoma viral oncogene homolog ; MAECs ; mouse aortic endothelial cells ; MAPK ; mitogen-activated protein kinase ; MEK ; MAPK ERK kinase ; MGO ; methylglyoxal ; miRNAs ; microRNAs ; NO ; nitric oxid

刊名：Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

出版年：2017

3.Neuronal overexpression of Glo1 or amygdalar microinjection of methylglyoxal is sufficient to regulate anxiety-like behavior in mice

作者：K.M.J. McMurray^a ; ^b ; X. Du^c ; M. Brownlee^c ; A.A. Palmer^a ; ^b ; ^d ; ^e ; ^{aap@ucsd.edu" class="auth_mail" title="E-mail the corresponding author}

关键词：GLO1 ; glyoxalase1 ; MG ; methylglyoxal ; OFT ; open-field test ; BLA ; basolateral amygdala ; pBBG ; S-bromobenzylglutathione cyclopentyl diester

刊名：Behavioural Brain Research

出版年：2016

4.A Glo1-Methylglyoxal Pathway that Is Perturbed in Maternal Diabetes Regulates Embryonic and Adult Neural Stem Cell Pools in Murine Offspring

作者：Guang Yang¹ ; Gonzalo I. Cancino¹ ; Siraj K. Zahr¹ ; ⁵ ; Axel Guskjolen¹ ; ² ; Anastassia Voronova¹ ; Denis Gallagher¹ ; Paul W. Frankland¹ ; ² ; ³ ; ⁵ ; David R. Kaplan¹ ; ⁴ ; ⁵ ; ^{dkaplan@sickkids.ca" class="auth_mail" title="E-mail the corresponding author} ; Freda D. Miller¹ ; ² ; ⁴ ; ⁵ ; ⁶ ; ^{fredam@sickkids.ca" class="auth_mail" title="E-mail the corresponding author}

关键词：neural stem cells ; neurogenesis ; cortical development ; Glyoxalase 1 ; methylglyoxal ; neurodevelopmental disorders ; maternal diabetes ; autism spectrum disorder

刊名：Cell Reports

出版年：2016

5.Glyoxalase I drives epithelial-to-mesenchymal transition via argpyrimidine-modified Hsp70, miR-21 and SMAD signalling in human bronchial cells BEAS-2B chronically exposed to crystalline silica Min-U-Sil 5: Transformation into a neoplastic-like phenotype

作者：Cinzia Antognelli^a ; ^{cinzia.antognelli@unipg.it" class="auth_mail" title="E-mail the corresponding author} ; Angela Gambelunghe^b ; ^{angela.gambelunghe@unipg.it" class="auth_mail" title="E-mail the corresponding author} ; Giacomo Muzi^b ; ^{giacomo.muzi@unipg.it" class="auth_mail" title="E-mail the corresponding author} ; Vincenzo Nicola Talesa^a ; ^{vincenzo.talesa@unipg.it" class="auth_mail" title="E-mail the corresponding author}

关键词：Glo1 ; Glyoxalase I ; MG ; Methylglyoxal ; AGEs ; Advanced glycation end products ; AP ; Argpyrimidine ; MS5 ; Min-U-Sil 5 ; EMT ; Epithelial to mesenchymal transition ; E-cad ; E-cadherin ; ZO-1 ; Zonula occludens-1 ; α-SMA ; α-smooth muscle actin ; ROS ; Reactive Oxygen Species ; miRNAs ; microRNAs ; TGF-β1 ; Transforming growth factor beta 1 ; IARC ; International Agency for Research on Cancer ; BEBM ; Bronchial Epithelial Cell Basal Medium ; BPE ; Bovine pituitary extract ; TRITC ; Tetramethylrhodamine B isothiocyanate ; D

刊名：Free Radical Biology and Medicine

出版年：2016

6.Determination of methylglyoxal in human blood plasma using fluorescence high performance liquid chromatography after derivatization with 1,2-diamino-4,5-methylenedioxybenzene

作者：Yuki Ogasawara^a ; ^{yo@my-pharm.ac.jp" class="auth_mail" title="E-mail the corresponding author} ; Ryo Tanaka^a ; Shin Koike^a ; Yasue Horiuchi^b ; Mitsuhiro Miyashita^b ; Makoto Arai^b

关键词：AGEs ; advanced glycated end products ; DDB ; 1 ; 2-diamino-4 ; 5-dimethoxybenzene ; DMB ; 1 ; 2-diamino-4 ; 5-methylenedioxy-benzene ; GLO1 ; glyoxalase 1 ; HPLC ; high-performance liquid chromatography ; LC&ndash ; MS/MS ; liquid chromatography tandem mass spectrometry ; LOD ; limit of detection ; LOQ ; limit of quantification ; MG ; methylglyoxal

刊名：Journal of Chromatography B, Analytical Technologies in the Biomedical and Life Sciences

出版年：2016

7.Hemolytic and antimalarial effects of tight-binding glyoxalase 1 inhibitors on the host-parasite unit of erythrocytes infected with Plasmodium falciparum

作者：Cletus A. Wezena^a ; ¹ ; Miriam Urscher^a ; ¹ ; Robert Vince^b ; Swati S. More^b ; Marcel Deponte^a ; ^{marcel.deponte@gmx.de" class="auth_mail" title="E-mail the corresponding author}

关键词：AGEs ; advanced glycation end products ; Glo1 ; glyoxalase 1 ; Glo2 ; glyoxalase 2 ; GSH ; reduced glutathione ; GSSG ; glutathione disulfide ; MG ; methylglyoxal ; Pf ; Plasmodium falciparum

刊名：Redox Biology

出版年：2016

8.Reduced glyoxalase 1 activity in carotid artery plaques of nondiabetic patients with increased hemoglobin A_1c level

作者：Andreas S. Peters ; MD^a ; ^b ; ^{andreas1.peters@med.uni-heidelberg.de" class="auth_mail" title="E-mail the corresponding author} ; Marieluise Lercher^a ; Thomas H. Fleming ; PhD^c ; ^d ; Peter P. Nawroth ; MD^c ; ^d ; ^e ; Moritz S. Bischoff ; MD^a ; Susanne Dihlmann ; PhD^a ; Dittmar Bö ; ckler ; MD^a ; Maani Hakimi ; MD^a ; ^b

刊名：Journal of Vascular Surgery

出版年：2016

9.A Caenorhabditis elegans Model Elucidates a Conserved Role for TRPA1-Nrf Signaling in Reactive α-Dicarbonyl Detoxification

作者：Jyotiska Chaudhuri¹ ; ⁵ ; Neelanjan Bose¹ ; ² ; ⁵ ; Jianke Gong³ ; ⁴ ; David Hall¹ ; Alexander Rifkind¹ ; Dipa Bhaumik¹ ; T. Harshani Peiris¹ ; Manish Chamoli¹ ; Catherine H. Le¹ ; Jianfeng Liu³ ; Gordon J. Lithgow¹ ; Arvind Ramanathan¹ ; X.Z. Shawn Xu⁴ ; Pankaj Kapahi¹ ; ² ; ⁶ ; ^{pkapahi@buckinstitute.org" class="auth_mail" title="E-mail the corresponding author}

关键词：Caenorhabditis elegans ; TRPA1 ; Nrf2 ; α-dicarbonyl stress ; advanced glycation endproducts ; Skn-1 ; diabetic complications ; neuropathy ; aging ; glyoxalase

刊名：Current Biology

出版年：2016

10.Differentiation and apoptosis induction by lovastatin and 纬-tocotrienol in HL-60 cells via Ras/ERK/NF-魏B and Ras/Akt/NF-魏B signaling dependent down-regulation of glyoxalase 1 and HMG-CoA reductase

作者：Chun-Chia Chen^a ; ^{tkc720901@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Tzu-Yu Liu^b ; ^{yubaby118@hotmail.com" class="auth_mail" title="E-mail the corresponding author} ; Shih-Pin Huang^b ; ^{wenily0617@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Chi-Tang Ho^c ; ^{ho@aesop.rutgers.edu" class="auth_mail" title="E-mail the corresponding author} ; Tzou-Chi Huang^a ; ^b ; ^{tchuang@mail.npust.edu.tw" class="auth_mail" title="E-mail the corresponding author}

关键词：GLO1 ; glyoxalase 1 ; HMGCR ; HMG-CoA reductase ; ERK ; extracellular signal regulated kinases ; Akt ; protein kinase B ; NF-魏B ; nuclear factor kappa-B ; MG ; methylglyoxal

刊名：Cellular Signalling

出版年：2015

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