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在“Elsevier电子期刊”中，命中：660条，耗时：小于0.01 秒

1.Computational prediction of the effects of non-synonymous single nucleotide polymorphisms in the human Quinone Oxidoreductase 1 (NQO1)

作者：Hidam Bishworjit Singh ^{hidam_bishworjit@yahoo.com} ; Dristi Deka ^{dristideka628@gmail.com} ; Dhiramani Das ^{dhiramanidas@rocketmail.com} ; Debasish Borbora ; ^{Debasish.borbora@gauhati.ac.in}

关键词：SNP ; Single nucleotide polymorphisms ; nsSNPs ; Non-synonymous SNPs ; NQO1 ; NAD(P)H Quinone Oxidoreductase 1 ; SIFT ; Sorting Intolerant from Tolerant ; PolyPhen ; phenotype polymorphism ; ROVEAN ; Protein Variation Effect Analyzer ; PDB ; Protein Data Bank ; GDT ; global distance test ; uGDT ; un-normalized GDT ; RMSD ; root mean squared deviation ; QMEAN ; Qualitative Model Energy Analysis ; ProSA ; Protein Structure Analysis ; UCSF ; University of California ; San Francisco

刊名：Meta Gene

出版年：2017

2.Rational construction of probes rendering ratiometric response to the cancer-specific enzyme NQO1

作者：Qiang Fei^a ; ^b ; Li Zhou^c ; Feiyi Wang^b ; Ben Shi^b ; Chunbao Li^a ; ^{lichunbao@tju.edu.cn" class="auth_mail" title="E-mail the corresponding author} ; Rui Wang^c ; Chunchang Zhao^b ; ^{zhaocchang@ecust.edu.cn" class="auth_mail" title="E-mail the corresponding author}

关键词：Cancer biomarker ; Polymeric micelle ; Nanoprobe ; Ratiometric ; Cancer-specific NQO1

刊名：Dyes and Pigments

出版年：2017

3.Distinct responses of compartmentalized glutathione redox potentials to pharmacologic quinones targeting NQO1

作者：Vladimir L. Kolossov ; ^{viadimer@illinois.edu} ; Nagendraprabhu Ponnuraj ; Jessica N. Beaudoin ; Matthew T. Leslie ; Paul J. Kenis ; H. Rex Gaskins

关键词：Redox homeostasis ; DNQ and β-lapachone ; NQO1 ; Lung and pancreatic cancer ; roGFP2 redox probe

刊名：Biochemical and Biophysical Research Communications

出版年：2017

4.Affinity-based small fluorescent probe for NAD(P)H:quinone oxidoreductase 1 (NQO1). Design, synthesis and pharmacological evaluation

作者：Jinlei Bian^a ; ¹ ; Xiang Li^a ; ¹ ; Lili Xu^a ; Nan Wang^a ; Xue Qian^a ; Qidong You^a ; ^{youqd@163.com} ; Xiaojin Zhang^a ; ^b ; ^{zxj@cpu.edu.cn}

关键词：Fluorescent probe ; NQO1 ; Inhibitor ; FITC ; Dicoumarol

刊名：European Journal of Medicinal Chemistry

出版年：2017

5.Activation of Akt and JNK/Nrf2/NQO1 pathway contributes to the protective effect of coptisine against AAPH-induced oxidative stress

作者：Yin-Ran Hu^a ; ^c ; ^d ; Hang Ma^a ; ^c ; ^d ; Zong-Yao Zou^a ; ^c ; ^d ; Kai He^a ; ^c ; ^d ; Yu-Bo Xiao^a ; ^c ; ^d ; Yue Wang^b ; Min Feng^a ; ^c ; ^d ; Xiao-Li Ye^b ; Xue-Gang Li^a ; ^c ; ^d ; ^{xuegangli@swu.edu.cn}

关键词：Coptisine (PubChem CID ; 72322) ; L-ascorbic acid (PubChem CID ; 54670067)

刊名：Biomedicine & Pharmacotherapy

出版年：2017

6.Overexpression of NAD(P)H:quinone oxidoreductase 1 (NQO1) and genomic gain of the NQO1 locus modulates breast cancer cell sensitivity to quinones

作者：Christophe Glorieux^a ; Juan Marcelo Sandoval^a ; Nicolas Dejeans^a ; ¹ ; Geneviè ; ve Ameye^b ; Hé ; lè ; ne Antoine Poirel^b ; Julien Verrax^a ; Pedro Buc Calderon^a ; ^c ; ^{pedro.buccalderon@uclouvain.be" class="auth_mail" title="E-mail the corresponding author}

关键词：NQO1 ; Breast cancer cells ; Genomic gain ; Menadione ; β-Lapachone ; Redox alterations

刊名：Life Sciences

出版年：2016

7.Individual effects of different selenocompounds on the hepatic proteome and energy metabolism of mice

作者：Claudia Lennicke^a ; Jette Rahn^a ; Anna P. Kipp^b ; Biljana P. Dojčinović^c ; Andreas S. Mü ; ller^d ; ^e ; Ludger A. Wessjohann^f ; Rudolf Lichtenfels^a ; Barbara Seliger^a ; ^{Barbara.Seliger@uk-halle.de}

关键词：AKT ; protein kinase B ; ARE ; anti-oxidant response elements ; CCB ; colloidal Coomassie Blue ; DIGE ; difference gel electrophoresis ; ERK ; extracellular regulated kinase ; Fasn ; fatty acid synthase ; Gck ; glucokinase ; Gpx/GPx ; glutathione peroxidase ; GS ; glutathione synthetase ; G6pc ; glucose-6-phosphatase ; GSH ; glutathione ; GST ; glutathione S-transferase ; Hprt ; hypoxanthine guanine ribosyl transferase ; Keap1 ; Kelch-like ECH-associated protein 1 ; NQO1 ; NAPH dehydrogenase 1 ; Nrf2 ; NF-E2-related factor 2

刊名：Biochimica et Biophysica Acta (BBA) - General Subjects

出版年：2017

8.Leveraging an NQO1 Bioactivatable Drug for Tumor-Selective Use of Poly(ADP-ribose) Polymerase Inhibitors

作者：Xiumei Huang¹ ; Edward A. Motea¹ ; Zachary R. Moore¹ ; Jun Yao¹ ; Ying Dong¹ ; Gaurab Chakrabarti¹ ; Jessica A. Kilgore² ; Molly A. Silvers¹ ; Praveen L. Patidar¹ ; Agnieszka Cholka¹ ; Farjana Fattah¹ ; Yoonjeong Cha³ ; Glenda G. Anderson⁴ ; Rebecca Kusko³ ; Michael Peyton⁵ ; Jingsheng Yan⁶ ; Xian-Jin Xie⁶ ; Venetia Sarode⁷ ; Noelle S. Williams² ; John D. Minna⁵ ; Muhammad Beg⁵ ; David E. Gerber⁵ ; Erik A. Bey⁸ ; ^{erik.bey@hsc.wvu.edu} ; David A. Boothman¹ ; ⁹ ; ^{david.boothman@utsouthwestern.edu}

关键词：NQO1 ; PARP1 ; β-lapachone ; NQO1 bioctivatable drugs ; Rucaparib ; Olaparib ; ARQ761 ; ROS ; NSCLC ; PDA ; combination chemotherapy ; synthetic lethality

刊名：Cancer Cell

出版年：2016

9.Ptgr1 expression is regulated by NRF2 in rat hepatocarcinogenesis and promotes cell proliferation and resistance to oxidative stress

作者：Ricardo Sá ; nchez-Rodrí ; guez^a ; Julia Esperanza Torres-Mena^a ; ^b ; Valeria Quintanar-Jurado^a ; Victoria Chagoya-Hazas^c ; Emilio Rojas del Castillo^d ; Luis del Pozo Yauner^a ; Saul Villa-Treviñ ; o^b ; Julio Isael Pé ; rez-Carreó ; n^a ; ^{jiperez@inmegen.gob.mx}

关键词：PTGR1 ; Prostaglandin reductase 1 ; HCC ; Hepatocellular carcinoma ; 4-HNE ; 4-hydroxynonenal ; NRF2 ; Nuclear Factor (erythroid-derived-2)-like-2 ; GCLC ; Glutamate-cysteine ligase ; catalytic subunit ; NQO1 ; NAD(P)H dehydrogenase quinone-1 ; GSTP1 ; Glutathione-S-transferase-P ; S&F ; Solt and Farber model ; DEN ; Schiffer protocol ; AHF ; Altered hepatocyte foci ; GGT ; γ-glutamyltransferase ; IHC ; immunochemistry ; PR ; Positive remodeling nodule ; NR ; Negative remodeling nodule ; P ; Persistent nodule ; NL ; Normal Liv

刊名：Free Radical Biology and Medicine

出版年：2017

10.Oxidative Damage Control in a Human (Mini-) Organ: Nrf2 Activation Protects against Oxidative Stress-Induced Hair Growth Inhibition

作者：Iain S. Haslam¹ ; ² ; ^{i.haslam@hud.ac.uk} ; Laura Jadkauskaite¹ ; Imre Lőrinc Szabó ; ³ ; Selma Staege¹ ; Jasper Hesebeck-Brinckmann¹ ; Gail Jenkins⁴ ; Ranjit K. Bhogal⁴ ; Fei-Ling Lim⁴ ; Nilofer Farjo⁵ ; Bessam Farjo⁵ ; Tamá ; s Bí ; ró ; ³ ; Matthias Schä ; fer⁶ ; Ralf Paus¹ ; ^{ralf.paus@manchester.ac.uk}

关键词：DP ; dermal papilla ; GSR ; glutathione reductase ; HF ; hair follicle ; HO-1 ; heme oxygenase-1 ; NQO1 ; NAD(P)H dehydrogenase ; quinone 1 ; Nrf2 ; nuclear factor (erythroid-derived 2)-like 2 ; ORS ; outer root sheath ; ORSK ; outer root sheath keratinocyte ; PRDX1 ; peroxiredoxin 1 ; ROS ; reactive oxygen species ; SFN ; sulforaphane ; siRNA ; small interfering RNA

刊名：Journal of Investigative Dermatology

出版年：2017

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