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在“Elsevier电子期刊”中，命中：1,451条，耗时：小于0.01 秒

1.Virtual screening and experimental validation identify novel modulators of nuclear receptor RXRα from Drugbank database

作者：Dan Xu¹ ; ^a ; Lijun Cai¹ ; ^a ; Shangjie Guo^a ; Lei Xie^a ; Meimei Yin^a ; Ziwen Chen^a ; Hu Zhou^a ; Ying Su^a ; ^b ; Zhiping Zeng^a ; ^{zengzhiping@xmu.edu.cn} ; Xiaokun Zhang^a ; ^b ; ^{xkzhang@xmu.edu.cn}

关键词：RXRα ; Old drug ; Agonist ; Antagonist ; Virtual screening

刊名：Bioorganic & Medicinal Chemistry Letters

出版年：2017

2.p53R2 regulates thioredoxin reductase activity through interaction with TrxR2

作者：Seon-Joo Park^a ; ^b ; ¹ ; Hong Beum Kim^a ; ^b ; ¹ ; Chunmei Piao^a ; Mi Yeong Kang^a ; Sang-Gon Park^c ; ^{sgpark@chosun.ac.kr} ; Seok Won Kim^d ; ^{chosunns@chosun.ac.kr} ; Jung-Hee Lee^a ; ^e ; ^{jhlee75@chosun.ac.kr}

关键词：p53R2 ; TrxR2 ; Mitochondria DNA repair ; Ribonucleotide reductase ; Thioredoxin reductase

刊名：Biochemical and Biophysical Research Communications

出版年：2017

3.The unexpected teratogenicity of RXR antagonist UVI3003 via activation of PPARγ in Xenopus tropicalis

作者：Jingmin Zhu^a ; Amanda Janesick^b ; Lijiao Wu^a ; Lingling Hu^a ; Weiyi Tang^b ; Bruce Blumberg^b ; Huahong Shi^a ; ^{hhshi@des.ecnu.edu.cn}

关键词：UVI3003 ; TPT ; Peroxisome proliferator activated receptor γ ; Retinoid X receptor ; Teratogenicity ; Xenopus

刊名：Toxicology and Applied Pharmacology

出版年：2017

4.Chiral separation and absolute configurations of two pairs of racemic polyprenylated benzophenones from Hypericum sampsonii

作者：Wen-Jing Tian^a ; ^c ; Yu-Qin Qiu^b ; Hai-Feng Chen^a ; Xiao-Jie Jin^e ; Xiao-Jun Yao^d ; ^e ; Yi Dai^b ; ^{daiyi1004@163.com} ; Xin-Sheng Yao^b ; ^c ; ^{tyaoxs@jnu.edu.cn}

关键词：Hypericum sampsonii ; PPBS ; biogenetic pathway ; RXRα transcriptional-inhibitory activities

刊名：Fitoterapia

出版年：2017

5.Brown Adipogenic Reprogramming Induced by a Small Molecule

作者：Baoming Nie¹ ; ⁸ ; Tao Nie² ; ³ ; ⁴ ; ⁸ ; Xiaoyan Hui⁵ ; ⁸ ; Ping Gu⁶ ; Liufeng Mao³ ; ⁴ ; Kuai Li³ ; ⁴ ; Ran Yuan³ ; ⁴ ; Jiashun Zheng⁷ ; Haixia Wang¹ ; Ke Li¹ ; Shibing Tang¹ ; Yu Zhang¹ ; Tao Xu¹ ; Aimin Xu⁵ ; Donghai Wu³ ; ⁴ ; ^{wu_donghai@gibh.ac.cn} ; Sheng Ding¹ ; ⁹ ; ^{sheng.ding@gladstone.ucsf.edu}

关键词：bexarotene ; RXR ; brown adipocyte ; C2C12 ; adipogenesis

刊名：Cell Reports

出版年：2017

6.TRC4, an improved triptolide derivative, specifically targets to truncated form of retinoid X receptor-alpha in cancer cells

作者：Pei-yu Wang^a ; ¹ ; Wen-jun Zeng^a ; ¹ ; Jie Liu^a ; ¹ ; Yun-Long Wu^a ; Yinghui Ma^a ; Zhiping Zeng^a ; Ji-yan Pang^b ; ^{cespjy@mail.sysu.edu.cn} ; Xiao-kun Zhang^a ; Xiaomei Yan^c ; Alice Sze Tsai Wong^d ; Jin-Zhang Zeng^a ; ^{jzzeng@xmu.edu.cn}

关键词：Truncated retinoic X receptor-alpha ; AKT ; Cancer ; Triptolide ; Derivatives

刊名：Biochemical Pharmacology

出版年：2017

7.Higher intake of cryptoxanthin is related to low body mass index and body fat in Japanese middle-aged women

作者：Asuka Hirose^a ; ^b ; ^{a-kacrm@tmd.ac.jp} ; Masakazu Terauchi^b ; ^{teragyne@tmd.ac.jp} ; Miho Hirano^a ; ^{120612ms@tmd.ac.jp} ; Mihoko Akiyoshi^a ; ^{akiyoshi@shonan.bunkyo.ac.jp} ; Yoko Owa^a ; ^{YIU72054@nifty.com} ; Kiyoko Kato^a ; ^{kiyoko2226@nifty.com} ; Toshiro Kubota^a ; ^{t.kubota.gyne@tmd.ac.jp}

关键词：ABC ; ATP-binding cassette transporter ; BDHQ ; brief-type self-administered diet history questionnaire ; BMI ; body mass index ; PPAR ; peroxisome proliferator-activated receptor ; RAR ; retinoic acid receptor ; RXR ; retinoid X receptor

刊名：Maturitas

出版年：2017

8.Bexarotene protects against traumatic brain injury in mice partially through apolipoprotein E

作者：Jianjun Zhong^a ; Chongjie Cheng^a ; Han Liu^a ; Zhijian Huang^a ; Yue Wu^a ; Zhipeng Teng^a ; Junchi He^a ; Hongrong Zhang^a ; Jinchuan Wu^a ; Fang Cao^b ; Li Jiang^a ; ; Xiaochuan Sun^a ;

关键词：BBB ; blood&ndash ; brain barrier ; CNS ; central nervous system ; CCI ; controlled cortical impact ; IOD ; integral optical density ; LXR ; liver X receptors ; PBS ; phosphate-buffered saline ; RXR ; retinoid X receptors ; TBI ; traumatic brain injury

刊名：Neuroscience

出版年：2017

9.Novel screening system for high-affinity ligand of heredity vitamin D-resistant rickets-associated vitamin D receptor mutant R274L using bioluminescent sensor

作者：Hiroki Mano^a ; Miyu Nishikawa^a ; ^b ; Kaori Yasuda^a ; Shinichi Ikushiro^a ; Nozomi Saito^c ; ¹ ; Daisuke Sawada^c ; ² ; Shinobu Honzawa^c ; ³ ; Masashi Takano^c ; Atsushi Kittaka^c ; Toshiyuki Sakaki^a ; ^b ; ^{tsakaki@pu-toyama.ac.jp}

关键词：VDR ; vitamin D receptor ; RXRα ; retinoid X receptor α ; LBD ; ligand binding domain ; VDRE ; vitamin D responsive element ; LucN ; N-terminal domain of luciferase ; LucC ; C-terminal domain of luciferase

刊名：The Journal of Steroid Biochemistry and Molecular Biology

出版年：2017

10.Possible involvement of Nrf2 and PPARγ up-regulation in the protective effect of umbelliferone against cyclophosphamide-induced hepatotoxicity

作者：Ayman M. Mahmoud^a ; ^{ayman.mahmoud@science.bsu.edu.eg} ; Mousa O. Germoush^b ; Mohammed F. Alotaibi^c ; Omnia E. Hussein^a

关键词：UMB ; umbelliferone ; PPARγ ; peroxisome proliferator activated receptor gamma ; CP ; cyclophosphamide ; Nrf2 ; nuclear factor erythroid 2-related factor 2 ; iNOS ; inducible nitric oxide synthase ; NF-κB ; nuclear factor-kappa B ; HO-1 ; heme oxygenase 1 ; ROS ; Reactive oxygen species ; Keap 1 ; Kelch-like ECH2-associated protein ; RXR ; retinoid X receptor ; ARE ; antioxidant response element ; ALP ; alkaline phosphatase ; ALT ; alanine aminotransferase ; AST ; aspartate aminotransferase ; MDA ; malondialdehyde ; NO ; nitr

刊名：Biomedicine & Pharmacotherapy

出版年：2017

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