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在“Elsevier电子期刊”中，命中：1,491条，耗时：0.0259881 秒

1.H19 mediates methotrexate resistance in colorectal cancer through activating Wnt/β-catenin pathway

作者：Ke-feng Wu^a ; ¹ ; Wei-Cheng Liang^b ; ¹ ; Lu Feng^c ; Jian-xin Pang^d ; Mary Miu-Yee Waye^b ; Jin-Fang Zhang^c ; Wei-Ming Fu^d ; ^{fuweiming76@smu.edu.cn}

关键词：CRC ; colorectal cancer ; DHFR ; dihydrofolate reductase ; DMEM ; Dulbecco's modified Eagle's medium ; lncRNAs ; long or large noncoding RNAs ; HT-29-R ; MTX-resistant colorectal cell line HT-29 ; MDR1 ; multi-drug resistance 1 ; MTT ; 3-(4 ; 5-Dimethylthiazol-2-yl)-2 ; 5-diphenyltetrazolium bromide ; MTX ; methotrexate ; PI ; propidium iodide ; siRNAs ; small interfering RNAs ; siH19 ; siRNAs specifically target human H19 ; pH19 ; the H19 overexpressing vector

刊名：Experimental Cell Research

出版年：2017

2.The RNAs of RNA-directed DNA methylation

作者：Jered M. Wendte^a ; Craig S. Pikaard^a ; ^b ; ^{cpikaard@indiana.edu}

关键词：AGO1 ; ARGONAUTE 1 ; AGO2 ; ARGONAUTE 2 ; AGO4 ; ARGONAUTE 4 ; AGO6 ; ARGONAUTE 6 ; CLSY1 ; CLASSY 1 ; CMT2 ; CHROMOMETHYLASE 2 ; CMT3 ; CHROMOMETHYLASE 3 ; CTD ; carboxy-terminal domain ; DCL1 ; DICER-LIKE 1 ; DCL2 ; DICER-LIKE 2 ; DCL3 ; DICER-LIKE 3 ; DCL4 ; DICER-LIKE 4 ; DDR ; DRD1-DMS3-RDM1 complex ; DMS11/ATMORC6 ; DEFECTIVE IN MERISTEM SILENCING 11/MICRORCHIDIA 6 ; DMS3 ; DEFECTIVE IN MERISTEM SILENCING 3 ; DNMT1 ; DNA METHYLTRANSFERASE 1 ; DNMT3 ; DNA METHYLTRANSFERASE 3 ; DRD1 ; DEFECTIVE IN RNA-DIRECTED DNA METHYLATION

刊名：Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms

出版年：2017

3.Suppression of protein tyrosine phosphatase PTPN22 gene induces apoptosis in T-cell leukemia cell line (Jurkat) through the AKT and ERK pathways

作者：Elham Baghbani^a ; ^b ; Behzad Baradaran^b ; Fatemeh Pak^a ; Leila Mohammadnejad^b ; Daryoush Shanehbandi^b ; Behzad Mansoori^b ; Vahid Khaze^b ; Noushin Montazami^b ; Ali Mohammadi^b ; Parviz Kokhaei^c ; ^d ; ^{Parviz.kokhaei@ki.se}

关键词：Protein tyrosine phosphatase non-receptor type 22 ; siRNA ; Jurkat ; Apoptosis ; AKT ; ERK ; T-cell leukemia

刊名：Biomedicine & Pharmacotherapy

出版年：2017

4.Challenges and opportunities for siRNA-based cancer treatment

作者：Tao Wang^a ; ^b ; Sarah Shigdar^b ; Hadi Al Shamaileh^b ; Michael P. Gantier^c ; ^d ; Wang Yin^b ; Dongxi Xiang^b ; Lan Wang^a ; Shu-Feng Zhou^e ; Yingchun Hou^f ; Peng Wang^a ; Weihong Zhang^a ; Chunwen Pu^g ; ^{dahaixiaowen@163.com} ; Wei Duan^b ; ^{wduan@deakin.edu.au}

关键词：RNA interference ; Tumour ; Nanoparticle ; EPR effect ; Endosome escape ; Off-target

刊名：Cancer Letters

出版年：2017

5.Liposome-polyethylenimine complexes (DPPC-PEI lipopolyplexes) for therapeutic siRNA delivery in vivo

作者：Alexander Ewe ; Dipl-Chem^a ; Omkar Panchal ; MSc^a ; Shashank Reddy Pinnapireddy ; MSc^b ; Udo Bakowsky ; PhD^b ; Susanne Przybylski ; Dipl-Biochem^c ; Achim Temme ; PhD^d ; Achim Aigner ; PhD^a ; ^{achim.aigner@medizin.uni-leipzig.de}

关键词：Lipopolyplex ; Polyethlyenimine ; Liposome ; siRNA therapy ; RNAi ; siRNA delivery ; Survivin

刊名：Nanomedicine: Nanotechnology, Biology and Medicine

出版年：2017

6.Intelligent substance delivery into cells using cell-penetrating peptides

作者：Toshihiko Tashima ^{tashima_lab@yahoo.co.jp}

关键词：CPP ; cell-penetrating peptide ; PTD ; protein transduction domain ; siRNA ; small interfering ribonucleic acid ; HIV-1 ; human immunodeficiency virus 1 ; Arg ; arginine ; Lys ; lysine ; Rn ; polyarginine composed of n arginines ; where n is natural number ; a.a. ; amino acids ; PI(4 ; 5)P2 ; phosphatidylinositol-4 ; 5-bisphosphate ; SLC transporter ; solute carrier transporter ; Rho GTPase ; guanosinetriphosphatase ; Fmoc ; 9-fluorenylmethyloxycarbonyl ; UV ; ultraviolet ; SDS-PAGE ; sodium dodecyl sulfate polyacrylamide gel

刊名：Bioorganic & Medicinal Chemistry Letters

出版年：2017

7.Involvement of PINK1/Parkin-mediated mitophagy in AGE-induced cardiomyocyte aging

作者：Zhimin Zha^a ; ¹ ; Junhong Wang^a ; ^b ; ¹ ; Xiangming Wang^a ; Miao Lu^a ; Yan Guo^a ; ^c ; ^{guoyan51@hotmail.com}

关键词：Advanced glycation end products ; Cardiac senescence ; Mitophagy ; Receptor for advanced glycation end products ; PINK1

刊名：International Journal of Cardiology

出版年：2017

8.Characteristics and processing of Pol IV-dependent transcripts in Arabidopsis

作者：Hsuan Yu Kuo^a ; ¹ ; Elise L. Jacobsen^a ; ¹ ; Yanping Long^b ; Xinyuan Chen^a ; Jixian Zhai^b ; ^a ; ^{zhaijx@sustc.edu.cn}

刊名：Journal of Genetics and Genomics

出版年：2017

9.Overcoming cisplatin resistance in non-small cell lung cancer with Mad2 silencing siRNA delivered systemically using EGFR-targeted chitosan nanoparticles

作者：Ana Vanessa Nascimento^a ; ^b ; ^c ; ^d ; Amit Singh^c ; Hassan Bousbaa^a ; ^e ; Domingos Ferreira^b ; Bruno Sarmento^a ; ^d ; Mansoor M. Amiji^c ; ^{m.amiji@neu.edu" class="auth_mail" title="E-mail the corresponding author}

关键词：Cisplatin resistance ; EGFR-targeted chitosan nanoparticles ; Mad2 siRNA delivery ; Non-small cell lung cancer models ; Efficacy ; Safety profile

刊名：Acta Biomaterialia

出版年：2017

10.Co-delivery of Se nanoparticles and pooled SiRNAs for overcoming drug resistance mediated by P-glycoprotein and class III β-tubulin in drug-resistant breast cancers

作者：Wenjing Zheng^a ; ¹ ; Tiantian Yin^a ; ¹ ; Qingchang Chen^a ; Xiuying Qin^a ; Xiaoquan Huang^a ; Shuang Zhao^a ; Taoyuan Xu^a ; Lanmei Chen^a ; ^b ; Jie Liu^a ; ^{tliuliu@jnu.edu.cn" class="auth_mail" title="E-mail the corresponding author}

关键词：Selenium ; siRNA ; Drug resistance ; P-glycoprotein ; Class III β-tubulin

刊名：Acta Biomaterialia

出版年：2016

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