作者：Ashton A. Connor (1) (2) (3) (4)
Hagit Katzov-Eckert (1)
Thomas Whelan (1)
Melyssa Aronson (1) (5)
Lynette Lau (6)
Christian Marshall (6) (7)
George S. Charames (8) (9)
Aaron Pollett (8) (9)
Steven Gallinger (1) (2) (3) (4) (5)
Jordan Lerner-Ellis (4) (8) (9)

1. Lunenfeld-Tanenbaum Research Institute ; Mount Sinai Hospital ; Toronto ; ON ; Canada
2. Institute of Medical Science ; University of Toronto ; Toronto ; ON ; Canada
3. Division of General Surgery ; Department of Surgery ; University of Toronto ; Toronto ; ON ; Canada
4. Ontario Institute for Cancer Research ; Toronto ; ON ; Canada
5. Zane Cohen Centre for Digestive Diseases ; Mount Sinai Hospital ; Toronto ; ON ; Canada
6. The Centre for Applied Genomics ; The Hospital for Sick Children ; Peter Gilgan Centre for Research and Learning ; Toronto ; ON ; Canada
7. The McLaughlin Centre ; University of Toronto ; Toronto ; ON ; Canada
8. Department of Laboratory Medicine and Pathobiology ; University of Toronto ; Toronto ; ON ; Canada
9. Department of Pathology and Laboratory Medicine ; Mount Sinai Hospital ; Toronto ; ON ; Canada

关键词：Gastrointestinal cancer ; DNA mismatch repair ; MSH6 ; Next generation sequencing ; Clinical genomics

刊名：Familial Cancer

出版年：2015

作者：Xin Wang (1) (2)
Adrian M. Dubuc (1) (2)
Vijay Ramaswamy (1) (2) (3)
Stephen Mack (1) (2)
Deena M. A. Gendoo (4)
Marc Remke (1) (2)
Xiaochong Wu (1)
Livia Garzia (1)
Betty Luu (1)
Florence Cavalli (1)
John Peacock (1) (2)
Borja L贸pez (1)
Patryk Skowron (1) (2)
David Zagzag (5)
David Lyden (6)
Caitlin Hoffman (1) (7)
Yoon-Jae Cho (8)
Charles Eberhart (9)
Tobey MacDonald (10)
Xiao-Nan Li (11)
Timothy Van Meter (12)
Paul A. Northcott (13)
Benjamin Haibe-Kains (14) (4)
Cynthia Hawkins (15)
James T. Rutka (7)
Eric Bouffet (3)
Stefan M. Pfister (13)
Andrey Korshunov (16)
Michael D. Taylor (1) (7)

1. Developmental and Stem Cell Biology Program ; The Hospital for Sick Children ; University of Toronto ; Toronto ; ON ; Canada
2. Department of Laboratory Medicine and Pathobiology ; University of Toronto ; Toronto ; ON ; Canada
3. Division of Haematology/Oncology ; Hospital for Sick Children ; Toronto ; ON ; Canada
4. Bioinformatics and Computational Genomics Laboratory ; Princess Margaret Cancer Centre ; University Health Network ; Toronto ; ON ; Canada
5. Departments of Pathology and Neurosurgery ; NYU Langone Medical Center ; New York ; NY ; USA
6. Departments of Pediatrics ; Cell and Developmental Biology ; Weill Medical College of Cornell University ; New York ; NY ; USA
7. Division of Neurosurgery ; Hospital for Sick Children ; 555 University Ave ; Ste 1503 ; Toronto ; ON ; M5C 1X8 ; Canada
8. Department of Neurology and Neurological Sciences ; Stanford University School of Medicine ; Stanford ; CA ; USA
9. Departments of Pathology ; Ophthalmology and Oncology ; John Hopkins University School of Medicine ; Baltimore ; MD ; USA
10. Pediatric Neuro-Oncology Program ; Emory University School of Medicine ; Atlanta ; GA ; USA
11. Department of Pediatrics ; Brain Tumor Program ; Children鈥檚 Cancer Center ; Baylor College of Medicine ; Houston ; TX ; USA
12. Department of Pediatrics ; Virginia Commonwealth University School of Medicine ; Richmond ; VA ; USA
13. Division of Pediatric Neurooncology ; Department of Pediatric Hematology and Oncology ; German Cancer Consortium (DKTK) ; German Cancer Research Center (DKFZ) ; Heidelberg University Hospital ; Heidelberg ; Germany
14. Department of Medical Biophysics ; University of Toronto ; Toronto ; ON ; Canada
15. Department of Pathology ; Hospital for Sick Children ; Toronto ; ON ; Canada
16. Clinical Cooperation Unit Neuropathology ; German Cancer Research Center (DKFZ) ; Heidelberg ; Germany

关键词：Medulloblastoma ; Metastasis ; Molecular subgroups ; Integrative genomics ; Gene expression ; DNA methylation

刊名：Acta Neuropathologica

出版年：2015

作者：Sylvia Papp (1) (2)
Sylvia L. Asa (1) (2)

1. Department of Pathology ; Laboratory Medicine Program ; University Health Network ; 200 Elizabeth Street ; 11th Floor ; Toronto ; ON ; M5G 2C4 ; Canada
2. Department of Laboratory Medicine and Pathobiology ; University of Toronto ; Toronto ; ON ; Canada

关键词：Thyroid carcinoma ; Angioinvasion ; Mutations ; Rearrangements ; Epigenetics

刊名：Head and Neck Pathology

出版年：2015

作者：Charis Kepron (1)
Michael S. Pollanen (2)

1. Ontario Forensic Pathology Service ; Department of Pathology and Laboratory Medicine ; University of Ottawa ; Ottawa ; Canada
2. Ontario Forensic Pathology Service ; Department of Laboratory Medicine and Pathobiology ; University of Toronto ; Toronto ; Canada

关键词：Forensic pathology ; Rickets ; Child abuse ; Classic metaphyseal lesion ; Fractures ; Pediatric

刊名：Forensic Science, Medicine, and Pathology

出版年：2015

作者：Martin D. Hyrcza (1) (2)
Daniel Winer (1) (3)
Ozgur Mete (1) (3)

1. Department of Pathology ; University Health Network ; 200 Elizabeth Street ; 11th floor ; Toronto ; ON ; M5G2C4 ; Canada
2. Department of Pathology and Laboratory Medicine ; University of British Columbia ; Vancouver ; BC ; Canada
3. Department of Laboratory Medicine and Pathobiology ; University of Toronto ; Toronto ; Canada

刊名：Endocrine Pathology

出版年：2015

作者：Hala Girgis (5) (6)
Olena Masui (7)
Nicole MA White (5) (6) (8)
Andreas Scorilas (9)
Fabio Rotondo (5) (6)
Annetta Seivwright (5) (6)
Manal Gabril (10)
Emily R Filter (10)
Andrew HA Girgis (5) (6)
Georg A Bjarnason (11)
Michael AS Jewett (12)
Andrew Evans (13) (8)
Sahar Al-Haddad (5) (6) (8)
KW Michael Siu (7)
George M Yousef (5) (6) (8)

5. The Keenan Research Center in the Li Ka Shing Knowledge Institute ; St. Michael鈥檚 Hospital ; Toronto ; M5B 1聽W8 ; Canada
6. Department of Laboratory Medicine ; St. Michael鈥檚 Hospital ; Toronto ; M5B 1聽W8 ; Canada
7. Department of Chemistry and Centre for Research in Mass Spectrometry ; York University ; 4700 Keele Street ; Toronto ; M3J 1P3 ; Canada
8. Department of Laboratory Medicine and Pathobiology ; University of Toronto ; Toronto ; M5S 1A8 ; Canada
9. Department of Biochemistry and Molecular Biology ; Faculty of Biology ; University of Athens ; 15701 ; Athens ; Greece
10. Department of Pathology ; London Health Sciences Center and Western University ; London ; N6A 5聽W9 ; Canada
11. Division of Medical Oncology and Hematology ; Sunnybrook Odette Cancer Center ; Toronto ; ON M4N 3聽M5 ; Canada
12. Division of Urologic Oncology ; Princess Margaret Hospital ; University Health Network ; Toronto ; ON M5G 2聽M9 ; Canada
13. Department of Laboratory Medicine ; University Health Network ; Toronto ; Canada

关键词：Lactate dehydrogenase A ; Prognosis ; Renal cell carcinoma ; Personalized medicine ; Tumor markers ; Proteomics ; Pathology ; Metastasis

刊名：Molecular Cancer

出版年：2014

作者：Daniela Cretu (1) (2)
Ioannis Prassas (1) (2)
Punit Saraon (1) (2)
Ihor Batruch (2)
Rajiv Gandhi (3) (4)
Eleftherios P Diamandis (1) (2) (5)
Vinod Chandran (3) (6) (7)

1. Department of Laboratory Medicine and Pathobiology ; University of Toronto ; Toronto ; Ontario ; Canada
2. Department of Pathology and Laboratory Medicine ; Mount Sinai Hospital ; Toronto ; Ontario ; Canada
3. Arthritis Program ; Toronto Western Hospital ; University Health Network ; 399 Bathurst Street ; Room 1E 416 ; Toronto ; ON ; M5T 2S8 ; Canada
4. Division of Orthopaedic Surgery ; Department of Surgery ; University of Toronto ; Toronto ; Canada
5. Department of Clinical Biochemistry ; University Health Network ; Toronto ; Ontario ; Canada
6. Psoriatic Arthritis Program ; Centre for Prognosis Studies in the Rheumatic Diseases ; Toronto Western Hospital ; Toronto ; Ontario ; Canada
7. Division of Rheumatology ; Department of Medicine ; University of Toronto ; Toronto ; Ontario ; Canada

关键词：Psoriatic arthritis ; Early osteoarthritis ; Proteomics ; Mass spectrometry ; Synovial fluid ; Selected reaction monitoring assays ; Proteins ; Mediators

刊名：Clinical Proteomics

出版年：2014

作者：Anand Bery (1) (2)
Felix Leung (1) (3)
Christopher R Smith (3)
Eleftherios P Diamandis (1) (2) (3)
Vathany Kulasingam (1) (2)

1. Department of Laboratory Medicine and Pathobiology ; University of Toronto ; Toronto ; ON ; Canada
2. Department of Clinical Biochemistry ; University Health Network ; Toronto ; ON ; Canada
3. Department of Pathology and Laboratory Medicine ; Lunenfeld-Tanenbaum Research Institute ; Mount Sinai Hospital ; Toronto ; ON ; Canada

关键词：Biomarker ; Early diagnosis ; Mass spectrometry ; Ovarian cancer ; Ascites fluid ; Peptidome

刊名：Clinical Proteomics

出版年：2014

作者：Jahangir Abdi (1) (2)
Lugui Qiu (3)
Hong Chang (1) (2) (3) (4)

1. Division of Molecular and Cellular Biology ; Toronto General Research Institute ; Toronto ; Canada
2. Department of Laboratory Medicine & Pathobiology ; University of Toronto ; 172 St George St ; Toronto ; ON ; M5R 0A3 ; Canada
3. Institute of Hematology and Blood Disease Hospital ; Chinese Academy of Medical Sciences and Peking Union Medical College ; Tianjin ; China
4. Department of Laboratory Hematology ; Laboratory Medicine Program ; Toronto General Hospital ; University Health Network ; 200 Elizabeth Street ; 11E-413 ; Toronto ; Ontario ; M5G 2C4 ; Canada

关键词：Multiple myeloma ; miRNA ; Bone marrow stroma ; CAMDR

刊名：Biomarker Research

出版年：2014

作者：Eleftherios P Diamandis (1) (2) (3) (4)

1. Department of Laboratory Medicine and Pathobiology ; University of Toronto ; Toronto ; Ontario ; Canada
2. Department of Pathology and Laboratory Medicine ; Mount Sinai Hospital ; Toronto ; Ontario ; Canada
3. Department of Clinical Biochemistry ; University Health Network ; Toronto ; Ontario ; Canada
4. Mount Sinai Hospital ; Joseph & Wolf Lebovic Ctr. 60 Murray St. (Box 32) ; Floor 6 ; Room L6-201 ; Toronto ; ON ; M5T 3 L9 ; Canada

关键词：Cancer biomarker ; Genomics ; Proteomics ; Mutant proteins ; High specificity ; Selected reaction monitoring ; Mass spectrometry

刊名：BMC Medicine

出版年：2014