作者：Jonathan A Cook (1) (2)
Jenni Hislop (3)
Douglas G Altman (1)
Peter Fayers (4) (5)
Andrew H Briggs (6)
Craig R Ramsay (2)
John D Norrie (7)
Ian M Harvey (8)
Brian Buckley (9)
Dean Fergusson (10)
Ian Ford (11)
Luke D Vale (3)
for the DELTA group

1. Centre for Statistics in Medicine ; Nuffield Department of Orthopaedics ; Rheumatology and Musculoskeletal Sciences ; University of Oxford ; Botnar Research Centre ; Nuffield Orthopaedic Centre ; Windmill Road ; Oxford ; OX3 7LD ; UK
2. Health Services Research Unit ; University of Aberdeen ; Health Sciences Building ; Foresthill ; Aberdeen ; AB25 2ZD ; UK
3. Institute of Health and Society ; Newcastle University ; The Baddiley-Clark Building ; Richardson Road ; Newcastle upon Tyne ; NE2 4AX ; UK
4. Population Health ; University of Aberdeen ; Polwarth Building ; Foresterhill ; Aberdeen ; AB25 2ZD ; UK
5. Department of Cancer Research and Molecular ; Norwegian University of Science and Technology ; Mailbox 8905 ; Trondheim ; N-7491 ; Norway
6. Health Economics and Health Technology Assessment ; University of Glasgow ; 1 Lilybank Gardens ; Glasgow ; G12 8RZ ; UK
7. Centre for Healthcare Randomised Trials (CHaRT) ; University of Aberdeen ; Health Sciences Building ; Aberdeen ; AB25 2ZD ; UK
8. Faculty of Medicine and Health Sciences ; University of East Anglia ; Elizabeth Fry Building ; Norwich Research Park ; Norwich ; NR4 7TJ ; UK
9. National University of Ireland ; University Road ; Galway ; Ireland
10. Clinical Epidemiology Program ; Ottawa Hospital Research Institute ; 725 Parkdale Avenue ; Ottawa ; ON ; K1Y 4E9 ; Canada
11. Robertson Centre for Biostatistics ; University of Glasgow ; Boyd Orr Building ; University Avenue ; Glasgow ; G12 8QQ ; UK

关键词：Target difference ; clinically important difference ; sample size ; randomised controlled trial ; guidance

刊名：Trials

出版年：2015