作者：Samia B Bachmann (1)
Sandra C Frommel (1) (2)
Rosalba Camicia (1) (3)
Hans C Winkler (1) (4)
Raffaella Santoro (1)
Paul O Hassa (1)

1. Institute of Veterinary Biochemistry and Molecular Biology ; University of Zurich ; Winterthurerstrasse 190 ; 8057 ; Zurich ; Switzerland
2. Molecular Life Science Program ; Life Science Zurich Graduate School ; University of Zurich ; Winterthurerstrasse 190 ; 8057 ; Zurich ; Switzerland
3. Stem Cell Research Laboratory ; NHS Blood and Transplant ; Nuffield Division of Clinical Laboratory Sciences ; Radcliffe Department of Medicine ; University of Oxford ; Oxford ; OX3 9DU ; UK
4. Institute of Pharmacology and Toxicology ; Vetsuisse Faculty ; University of Zurich ; Winterthurerstrasse 260 ; 8057 ; Zurich ; Switzerland

关键词：Metastatic prostate cancer ; Mono ; ADP ; ribosyltransferase ; ARTD9/PARP9 ; ARTD8/PARP14 ; E3 ubiquitin ligase ; DTX3L/BBAP ; Proliferation ; Survival ; Migration ; STAT1 ; STAT3

刊名：Molecular Cancer

出版年：2014

作者：Hyungju Park (1)
Kyung-Seok Han (1) (2)
Jinsoo Seo (3)
Jaekwang Lee (1)
Shashank M Dravid (4)
Junsung Woo (1) (2)
Heejung Chun (1)
Sukhee Cho (3)
Jin Young Bae (5)
Heeyoung An (1) (6)
Woohyun Koh (1) (2)
Bo-Eun Yoon (1) (7)
Rolando Berlinguer-Palmini (8)
Guido Mannaioni (9)
Stephen F Traynelis (10)
Yong Chul Bae (5)
Se-Young Choi (3)
C Justin Lee (1) (2) (6)

1. Center for Neural Science ; Korea Institute of Science and Technology (KIST) ; Seoul ; Korea
2. Neuroscience Program ; University of Science and Technology (UST) ; Daejeon ; Korea
3. Department of Physiology and Dental Research Institute ; Seoul National University School of Dentistry ; Seoul ; Korea
4. Department of Pharmacology ; Creighton University ; Omaha ; NE ; USA
5. Department of Oral Anatomy and Neurobiology ; School of Dentistry ; Kyungpook National University ; Daegu ; Korea
6. KU-KIST Graduate School of Converging Science and Technology ; Seoul ; Korea
7. Department of Nanobiomedical Science ; Dankook University ; Cheonan ; Korea
8. School of Electrical and Electronic Engineering ; Institute of Neuroscience ; Newcastle University ; Newcastle upon Tyne ; UK
9. Department of Pharmacology ; University of Florence ; Florence ; Italy
10. Department of Pharmacology ; Emory University ; Atlanta ; GA ; USA

关键词：Astrocytes ; Bestrophin 1 ; Ca2+ ; activated anion channel ; Synaptic plasticity ; Glutamate ; NMDA receptor ; LTP ; PAR1

刊名：Molecular Brain

出版年：2015

作者：David Sweeney (1) (2)
Fay Hollins (1)
Edith Gomez (1) (2)
Rajendra Mistry (2)
Ruth Saunders (1)
Robert Alfred John Challiss (2)
Christopher Edward Brightling (1)

1. Department of Infection ; Immunity & Inflammation ; and Institute for Lung Health ; University of Leicester ; Glenfield Hospital ; Leicester ; LE3 9QP ; UK
2. Department of Cell Physiology & Pharmacology ; University of Leicester ; Henry Wellcome Building ; Lancaster Road ; Leicester ; LE1 9HN ; UK

关键词：Asthma ; Airway smooth muscle ; Calcium ; Sarco/endoplasmic reticulum Ca2+ ATPase type 2 (SERCA2) ; Inositol 145 ; trisphosphate

刊名：BMC Pulmonary Medicine

出版年：2015

作者：Truls S. Ingebrigtsen M.D. (1) (2) (3)
Jacob L. Marott Statistician. (2)
B酶rge G. Nordestgaard M.D. ; D.M.Sc. (2) (3) (4)
Peter Lange M.D. ; D.M.Sc. (2) (3) (5) (6)
Jesper Hallas M.D. ; D.M.Sc. (7)
Morten Dahl M.D. ; D.M.Sc. (8)
J酶rgen Vestbo M.D. ; D.M.Sc. (1) (9)

1. Department of Respiratory Medicine ; Odense University Hospital ; and Institute of Clinical Research ; University of Southern Denmark ; Sdr. Boulevard 29 ; 5000 ; Odense C ; Denmark
2. The Copenhagen City Heart Study ; Frederiksberg Hospital ; Copenhagen ; Denmark
3. The Copenhagen General Population Study ; Herlev Hospital ; Copenhagen University Hospital ; University of Copenhagen ; Copenhagen ; Denmark
4. Department of Clinical Biochemistry ; Herlev Hospital ; Copenhagen University Hospital ; University of Copenhagen ; Copenhagen ; Denmark
5. Respiratory Section ; Hvidovre Hospital ; Copenhagen University Hospital ; University of Copenhagen ; Copenhagen ; Denmark
6. Department of Social Medicine ; Institute of Public Health ; University of Copenhagen ; Copenhagen ; Denmark
7. Department of Clinical Pharmacology ; University of Southern Denmark ; Odense ; Denmark
8. Department of Clinical Biochemistry ; Rigshospitalet ; Copenhagen University Hospital ; University of Copenhagen ; Copenhagen ; Denmark
9. Respiratory and Allergy Research Group ; Manchester Academic Health Science Centre ; University Hospital South Manchester NHS Foundation Trust ; Manchester ; UK

关键词：COPD ; severity ; GOLD ; long ; acting medication

刊名：Journal of General Internal Medicine

出版年：2015

作者：S. Lowes (1)
R. Hucker (2)
M. Jemal (3)
J. C. Marini (4)
V. M. Rezende (5)
R. Shoup (6)
P. Singhal (7)
P. Timmerman (8)
T. Yoneyama (9)
N. Weng (10)
D. Zimmer (11)

1. Bioanalytical and ADME Labs ; Quintiles ; 19 Brown Road ; Ithaca ; New York ; 14850 ; USA
2. A4P Consulting Ltd. ; Discovery Park ; Sandwich ; Kent ; CT13 9ND ; UK
3. 931 Edinburg Road ; Hamilton Square ; New Jersey ; 08690 ; USA
4. Biologics Clinical Pharmacology ; Janssen Research and Development ; LLC ; 1400 McKean Road ; Spring House ; Pennsylvania ; 19477 ; USA
5. Department of Hematology ; School of Medicine ; University of S茫o Paulo ; S茫o Paulo ; Brazil
6. AIT Bioscience ; LLC ; 7840 Innovation Blvd ; Indianapolis ; Indiana ; 46278 ; USA
7. Alkem Laboratories Ltd ; C-17/7 ; MIDC Industrial Estate ; Taloja ; Navi Mumbai ; Mumbai ; 410208 ; India
8. Janssen Research & Development ; Turnhoutseweg 30 ; 2340 ; Beerse ; Belgium
9. Drug Metabolism and Pharmacokinetics Research Laboratories ; Pharmaceutical Research Division ; Takeda Pharmaceutical Company Limited ; 26-1 ; Muraoka-Higashi 2-Chome ; Fujisawa ; Kanagawa ; 251-8555 ; Japan
10. Pharmacokinetics ; Dynamics & Metabolism ; Janssen Research and Development ; 1400 McKean Road ; Spring House ; Pennsylvania ; 19477 ; USA
11. Zimmer BioAnalytics & More ; St. Alban-Ring 282 ; CH-4052 ; Basel ; Switzerland

关键词：bioanalysis ; chromatographic ; regulated ; tiered approaches

刊名：The AAPS Journal

出版年：2015

作者：Kayode Ogungbenro (1)
Henry Pertinez (1) (2)
Leon Aarons (1)

1. Centre for Applied Pharmacokinetic Research ; Manchester Pharmacy School ; The University of Manchester ; Oxford Road ; Manchester ; M13 9PT ; UK
2. Department of Clinical & Molecular Pharmacology ; University of Liverpool ; Liverpool ; L69 3GF ; UK

关键词：double ; peak ; gastric emptying ; levodopa ; modelling ; paracetamol ; scintigraphy

刊名：The AAPS Journal

出版年：2015

作者：M. Benjamin Hock (1)
Karen E. Thudium (2)
Montserrat Carrasco-Triguero (3)
Nikolai F. Schwabe (4)

1. Department of Clinical Immunology ; Amgen Inc. ; One Amgen Center Dr. ; 30E-3-B ; Thousand Oaks ; California ; 91320 ; USA
2. Oncology Clinical Pharmacology ; Novartis Pharmaceuticals ; One Health Plaza ; BLDG 337 ; East Hanover ; New Jersey ; 07936 ; USA
3. BioAnalytical Sciences ; Genentech ; South San Francisco ; California ; USA
4. ProImmune Ltd. ; Oxford ; UK

关键词：antibody ; drug conjugate (ADC) ; antidrug antibodies (ADA) ; bioanalytical ; immunogenicity ; oncology

刊名：The AAPS Journal

出版年：2015

作者：Quan Yang (1) (2)
Richard H. Guy (1)

1. Department of Pharmacy & Pharmacology ; University of Bath ; Claverton Down ; Bath ; BA2 7AY ; UK
2. MHRA ; 151 Buckingham Palace Road ; London ; SW1W 9SZ ; UK

关键词：infrared spectroscopy ; reverse iontophoresis ; skin barrier function natural moisturizing factor (NMF) ; stratum corneum

刊名：Pharmaceutical Research

出版年：2015

作者：V. L. M. Yip (1)
A. Alfirevic (1)
M. Pirmohamed (1)

1. Department of Molecular and Clinical Pharmacology ; The University of Liverpool ; The Wolfson Centre for Personalised Medicines ; Block A ; Waterhouse Buildings 1-5 Prescot Street ; Liverpool ; L69 3GL ; UK

关键词：Adverse drug reactions ; Drug ; induced skin injury ; Drug ; induced liver injury ; Human leukocyte antigen ; Maculopapular exanthema ; Hypersensitivity syndrome ; Stevens ; Johnson syndrome ; Hypersensitivity ; Abacavir ; Allopurinol ; Carbamazepine ; Flucloxacillin ; Ximelagatran

刊名：Clinical Reviews in Allergy & Immunology

出版年：2015

作者：Jonathan C Rodrigues (167) (168)
Emma C Hart (168) (169)
Neelam Hassan (170)
Mandy Williams (171)
Amy E Burchell (169)
Laura E Ratcliffe (169)
Angus K Nightingale (169)
Julian F Paton (168) (169)
Nathan E Manghat (167)

167. CMR Unit ; NIHR Cardiovascular Biomedical Research Unit ; Bristol Heart Institute ; Bristol ; UK
168. School of Physiology and Pharmacology ; The University of Bristol ; Bristol ; UK
169. Cardionomics Research Group ; Bristol Heart Institute ; Bristol ; UK
170. Foundation School ; Severn Postgraduate Deanery ; Bristol ; UK
171. Department of Radiology ; Bristol Royal Infirmary ; Bristol ; UK

刊名：Journal of Cardiovascular Magnetic Resonance

出版年：2015