作者： Yoshito Hirata ; Kai Morino ; Taiji Suzuki ; Qian Guo…

关键词：mathematical medicine ; dynamical model ; parameter estimation

刊名：Quantitative Biology

出版年：2016

作者：Fei Chen (1)
Xueqian Zhuang (1)
Liangyu Lin (1)
Pengfei Yu (1)
Ying Wang (1)
Yufang Shi (1) (2)
Guohong Hu (1)
Yu Sun (1) (3) (4) (5)

1. Key Laboratory of Stem Cell Biology ; Institute of Health Sciences ; Shanghai Institutes for Biological Sciences ; Chinese Academy of Sciences/Shanghai Jiaotong University School of Medicine ; Shanghai ; 200031 ; China
2. Soochow Institutes for Translational Medicine ; Soochow University ; Suzhou ; 215123 ; China
3. VA Seattle Medical Center ; Seattle ; WA ; 98108 ; USA
4. Department of Medicine ; University of Washington ; Seattle ; WA ; 98195 ; USA
5. Institute of Health Sciences ; Shanghai Institutes for Biological Sciences (SIBS) ; Chinese Academy of Sciences (CAS) and Shanghai Jiaotong University School of Medicine (SJTUSM) ; 320 Yue Yang Road ; Biological Research Building A ; Shanghai ; 200031 ; China

关键词：Acquired resistance ; Clinical oncology ; Combination therapy ; Distant metastasis ; Immunomodulation ; Targeting strategy ; Therapeutic intervention ; Translational medicine ; Tumor microenvironment

刊名：BMC Medicine

出版年：2015

作者：Erich D Jarvis (1)
Siavash Mirarab (2)
Andre J Aberer (3)
Bo Li (4) (5) (6)
Peter Houde (7)
Cai Li (4) (6)
Simon Y W Ho (8)
Brant C Faircloth (10) (9)
Benoit Nabholz (11)
Jason T Howard (1)
Alexander Suh (12)
Claudia C Weber (12)
Rute R da Fonseca (6)
Alonzo Alfaro-N煤帽ez (6)
Nitish Narula (13) (7)
Liang Liu (14)
Dave Burt (15)
Hans Ellegren (12)
Scott V Edwards (16)
Alexandros Stamatakis (17) (3)
David P Mindell (18)
Joel Cracraft (19)
Edward L Braun (20)
Tandy Warnow (2)
Wang Jun (21) (22) (23) (24) (4)
M Thomas Pius Gilbert (25) (6)
Guojie Zhang (26) (4)
The Avian Phylogenomics Consortium

1. Department of Neurobiology ; Howard Hughes Medical Institute and Duke University Medical Center ; Durham ; NC ; 27710 ; USA
2. Department of Computer Science ; The University of Texas at Austin ; Austin ; TX ; 78712 ; USA
3. Scientific Computing Group ; Heidelberg Institute for Theoretical Studies ; Heidelberg ; Germany
4. China National GeneBank ; BGI-Shenzhen ; Shenzhen ; 518083 ; China
5. College of Medicine and Forensics ; Xi鈥檃n Jiaotong University ; Xi鈥檃n ; 710061 ; China
6. Centre for GeoGenetics ; Natural History Museum of Denmark ; University of Copenhagen ; 脴ster Voldgade 5-7 ; 1350 ; Copenhagen ; Denmark
7. Department of Biology ; New Mexico State University ; Las Cruces ; NM ; 88003 ; USA
8. School of Biological Sciences ; University of Sydney ; Sydney ; NSW ; 2006 ; Australia
10. Department of Biological Sciences ; Louisiana State University ; Baton Rouge ; LA ; 70803 ; USA
9. Department of Ecology and Evolutionary Biology ; University of California Los Angeles ; Los Angeles ; CA ; 90095 ; USA
11. CNRS UMR 5554 ; Institut des Sciences de l鈥橢volution de Montpellier ; Universit茅 Montpellier II ; Montpellier ; France
12. Department of Evolutionary Biology ; Uppsala University ; SE-752 36 ; Uppsala ; Sweden
13. Biodiversity and Biocomplexity Unit ; Okinawa Institute of Science and Technology Onna-son ; Okinawa ; 904-0495 ; Japan
14. Department of Statistics and Institute of Bioinformatics ; University of Georgia ; Athens ; 30602 ; USA
15. Department of Genomics and Genetics ; The Roslin Institute and Royal (Dick) School of Veterinary Studies ; University of Edinburgh ; Easter Bush Campus ; Midlothian ; EH25 9RG ; UK
16. Department of Organismic and Evolutionary Biology and Museum of Comparative Zoology ; Harvard University ; Cambridge ; MA ; USA
17. Institute of Theoretical Informatics ; Department of Informatics ; Karlsruhe Institute of Technology ; D- 76131 ; Karlsruhe ; Germany
18. Department of Biochemistry & Biophysics ; University of California ; San Francisco ; CA ; 94158 ; USA
19. Department of Ornithology ; American Museum of Natural History ; New York ; NY ; 10024 ; USA
20. Department of Biology and Genetics Institute ; University of Florida ; Gainesville ; FL ; 32611 ; USA
21. Department of Biology ; University of Copenhagen ; Ole Maal酶es Vej 5 ; 2200 ; Copenhagen ; Denmark
22. Princess Al Jawhara Center of Excellence in the Research of Hereditary Disorders ; King Abdulaziz University ; Jeddah ; 21589 ; Saudi Arabia
23. Macau University of Science and Technology ; Avenida Wai long ; Taipa ; Macau ; 999078 ; China
24. Department of Medicine ; University of Hong Kong ; Hong Kong ; Hong Kong
25. Trace and Environmental DNA Laboratory Department of Environment and Agriculture ; Curtin University ; Perth ; WA ; 6102 ; Australia
26. Centre for Social Evolution ; Department of Biology ; Universitetsparken 15 ; University of Copenhagen ; DK-2100 ; Copenhagen ; Denmark

关键词：Avian genomes ; Phylogenomics ; Sequence alignments ; Species tree ; Gene trees ; Indels ; Transposable elements

刊名：GigaScience

出版年：2015

作者：N. Eymard (1)
N. Bessonov (2)
O. Gandrillon (3) (4)
M. J. Koury (5)
V. Volpert (1) (4) (6)

1. Institut Camille Jordan ; UMR 5208 CNRS ; University Lyon 1 ; Villeurbanne ; France
2. Institute of Mechanical Engineering Problems ; 199178聽 ; Saint Petersburg ; Russia
3. Centre de G茅n茅tique et de Physiologie Mol茅culaire et Cellulaire ; CNRS UMR 5534 ; University Lyon 1 ; Villeurbanne聽 ; 69622 ; France
4. INRIA Team Dracula ; INRIA Antenne Lyon la Doua ; Villeurbanne ; 69603聽 ; France
5. Medicine ; Veterans Affairs Tennessee Valley Healthcare System and Vanderbilt University Medical Center ; Nashville ; TN ; USA
6. European Institute of Systems Biology and Medicine ; Lyon聽 ; 69007 ; France

关键词：Erythropoiesis ; Erythroblastic island ; Hybrid model ; Comparison with experiments ; 92C37 ; 68U20

刊名：Journal of Mathematical Biology

出版年：2015

作者：Muneesh Tewari (1)

1. Departments of Internal Medicine and Bioengineering ; Biointerfaces Institute and Center for Computational Medicine and Bioinformatics ; University of Michigan ; 109 Zina Pitcher Place ; 4029 BSRB ; SPC 2200 ; Ann Arbor ; MI ; 48109-2200 ; USA

刊名：Genome Biology

出版年：2015

作者：Talha Ijaz (1)
Konrad Pazdrak (1) (2) (3)
Mridul Kalita (2) (4)
Rolf Konig (2) (5)
Sanjeev Choudhary (1) (2) (5)
Bing Tian (4)
Istvan Boldogh (1) (2) (5)
Allan R Brasier (2) (3) (4)

1. Department of Biochemistry and Molecular Biology ; The University of Texas Medical Branch ; 301 University Blvd ; Galveston ; 77555-1060 ; Texas ; USA
2. Sealy Center for Molecular Medicine ; The University of Texas Medical Branch ; 301 University Blvd ; Galveston ; 77555-1060 ; Texas ; USA
3. Institute for Translational Sciences ; The University of Texas Medical Branch ; 301 University Blvd ; Galveston ; 77555-1060 ; Texas ; USA
4. Department of Internal Medicine ; The University of Texas Medical Branch ; 301 University Blvd ; Galveston ; 77555-1060 ; Texas ; USA
5. Department of Microbiology and Immunology ; The University of Texas Medical Branch ; 301 University Blvd ; Galveston ; 77555-1060 ; Texas ; USA

关键词：EMT ; Inflammation ; NF ; 魏B ; TGF尾 ; Eosinophils ; Systems biology ; Innate immunity

刊名：World Allergy Organization Journal

出版年：2014

作者：Xin Wang (1) (2)
Adrian M. Dubuc (1) (2)
Vijay Ramaswamy (1) (2) (3)
Stephen Mack (1) (2)
Deena M. A. Gendoo (4)
Marc Remke (1) (2)
Xiaochong Wu (1)
Livia Garzia (1)
Betty Luu (1)
Florence Cavalli (1)
John Peacock (1) (2)
Borja L贸pez (1)
Patryk Skowron (1) (2)
David Zagzag (5)
David Lyden (6)
Caitlin Hoffman (1) (7)
Yoon-Jae Cho (8)
Charles Eberhart (9)
Tobey MacDonald (10)
Xiao-Nan Li (11)
Timothy Van Meter (12)
Paul A. Northcott (13)
Benjamin Haibe-Kains (14) (4)
Cynthia Hawkins (15)
James T. Rutka (7)
Eric Bouffet (3)
Stefan M. Pfister (13)
Andrey Korshunov (16)
Michael D. Taylor (1) (7)

1. Developmental and Stem Cell Biology Program ; The Hospital for Sick Children ; University of Toronto ; Toronto ; ON ; Canada
2. Department of Laboratory Medicine and Pathobiology ; University of Toronto ; Toronto ; ON ; Canada
3. Division of Haematology/Oncology ; Hospital for Sick Children ; Toronto ; ON ; Canada
4. Bioinformatics and Computational Genomics Laboratory ; Princess Margaret Cancer Centre ; University Health Network ; Toronto ; ON ; Canada
5. Departments of Pathology and Neurosurgery ; NYU Langone Medical Center ; New York ; NY ; USA
6. Departments of Pediatrics ; Cell and Developmental Biology ; Weill Medical College of Cornell University ; New York ; NY ; USA
7. Division of Neurosurgery ; Hospital for Sick Children ; 555 University Ave ; Ste 1503 ; Toronto ; ON ; M5C 1X8 ; Canada
8. Department of Neurology and Neurological Sciences ; Stanford University School of Medicine ; Stanford ; CA ; USA
9. Departments of Pathology ; Ophthalmology and Oncology ; John Hopkins University School of Medicine ; Baltimore ; MD ; USA
10. Pediatric Neuro-Oncology Program ; Emory University School of Medicine ; Atlanta ; GA ; USA
11. Department of Pediatrics ; Brain Tumor Program ; Children鈥檚 Cancer Center ; Baylor College of Medicine ; Houston ; TX ; USA
12. Department of Pediatrics ; Virginia Commonwealth University School of Medicine ; Richmond ; VA ; USA
13. Division of Pediatric Neurooncology ; Department of Pediatric Hematology and Oncology ; German Cancer Consortium (DKTK) ; German Cancer Research Center (DKFZ) ; Heidelberg University Hospital ; Heidelberg ; Germany
14. Department of Medical Biophysics ; University of Toronto ; Toronto ; ON ; Canada
15. Department of Pathology ; Hospital for Sick Children ; Toronto ; ON ; Canada
16. Clinical Cooperation Unit Neuropathology ; German Cancer Research Center (DKFZ) ; Heidelberg ; Germany

关键词：Medulloblastoma ; Metastasis ; Molecular subgroups ; Integrative genomics ; Gene expression ; DNA methylation

刊名：Acta Neuropathologica

出版年：2015

作者：Peng Yao (1)
Sandeepa M. Eswarappa (1)
Paul L. Fox (1)

1. Department of Cellular and Molecular Medicine ; Cleveland Clinic Lerner Research Institute ; 9500 Euclid Avenue/NC10 ; Cleveland ; OH ; 44195 ; USA

关键词：Angiogenesis ; Atherosclerosis ; GAIT ; MicroRNA ; Translational control ; Vascular endothelial growth factor

刊名：Current Atherosclerosis Reports

出版年：2015

作者：Traci L Marin (1) (5)
Brendan Gongol (1) (5)
Marcy Martin (1) (2)
Stephanie J King (1)
Lemar Smith (1)
David A Johnson (1)
Shankar Subramaniam (3)
Shu Chien (3) (4)
John Y-J Shyy (1) (2)

1. Divisions of Biochemistry and Molecular Biology and Biomedical Sciences ; University of California ; Riverside ; CA ; 92521-0121 ; USA
5. Department of Cardiopulmonary Sciences and Anatomy ; Schools of Allied Health and Medicine ; Loma Linda University ; Loma Linda ; CA ; 92350 ; USA
2. Division of Cardiology ; Department of Medicine ; University of California ; San Diego ; La Jolla ; CA ; 92093 ; USA
3. Division of Physiology ; Department of Medicine ; University of California ; San Diego ; La Jolla ; CA ; 92093 ; USA
4. Department of Bioengineering and Institute of Engineering in Medicine ; University of California ; San Diego La Jolla ; CA ; 92093 ; USA

关键词：AMPK ; AKT2 ; ATF2 ; MMP2 ; FOXO3a ; NADSYN1 ; Phosphorylation consensus sequence ; Bioinformatics ; Proteome ; Network prediction

刊名：BMC Systems Biology

出版年：2015

作者：Mamatha Damodarasamy (1)
Robert B. Vernon (2)
Christina K. Chan (2)
Stephen R. Plymate (1) (3)
Thomas N. Wight (2)
May J. Reed (1)

1. Department of Medicine ; University of Washington ; Harborview Medical Center ; 325 9th Avenue ; Box 359625 ; Seattle ; WA ; 98104 ; USA
2. Matrix Biology Program ; Benaroya Research Institute at Virginia Mason ; 1201 9th Avenue ; Seattle ; WA ; 98101 ; USA
3. Veterans Affairs Puget Sound Health Care System ; Seattle ; Washington ; USA

关键词：Aging ; Benign prostatic hypertrophy ; Collagen gel ; 3 ; Dimensional ; Extracellular matrix ; In vitro

刊名：In Vitro Cellular & Developmental Biology - Animal

出版年：2015