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Elsevier电子期刊(96)

在“Elsevier电子期刊”中，命中：96条，耗时：小于0.01 秒

在所有数据库中总计命中：96条

1.Genomic Biomarkers of a Randomized Trial Comparing First-line Everolimus and Sunitinib in Patients with Metastatic Renal Cell Carcinoma

作者：James J. Hsieh^a ; ^{hsiehj@mskcc.org} ; David Chen^b ; Patricia I. Wang^a ; Mahtab Marker^b ; Almedina Redzematovic^a ; Ying-Bei Chen^a ; S. Duygu Selcuklu^a ; Nils Weinhold^a ; Nancy Bouvier^a ; Kety H. Huberman^a ; Umesh Bhanot^a ; Michael S. Chevinsky^a ; ^c ; Parul Patel^b ; Patrizia Pinciroli^a ; ^d ; Helen H. Won^a ; Daoqi You^a ; Agnes Viale^a ; William Lee^a ; A. Ari Hakimi^a ; Michael F. Berger^a ; Nicholas D. Socci^a ; Emily H. Cheng^a ; Jennifer Knox^e ; Martin H. Voss^a ; Maurizio Voi^b ; Robert J. Motzer^a

关键词：Genomic biomarker ; Kidney cancer ; Targeted therapy ; Everolimus ; Sunitinib ; Tumor suppressor gene ; PBRM1 ; SETD2 ; BAP1 ; KDM5C

刊名：European Urology

出版年：2017

2.Lead optimization of a pyrazolo[1,5-a]pyrimidin-7(4H)-one scaffold to identify potent, selective and orally bioavailable KDM5 inhibitors suitable for in vivo biological studies

作者：Jun Liang^a ; ^{liang.jun@gene.com" class="auth_mail" title="E-mail the corresponding author} ; Birong Zhang^a ; Sharada Labadie^a ; Daniel F. Ortwine^a ; Maia Vinogradova^a ; James R. Kiefer^a ; Victor S. Gehling^b ; Jean-Christophe Harmange^b ; Richard Cummings^b ; Tommy Lai^c ; Jiangpeng Liao^c ; Xiaoping Zheng^c ; Yichin Liu^a ; Amy Gustafson^a ; Erica Van der Porten^a ; Weifeng Mao^c ; Bianca M. Liederer^a ; Gauri Deshmukh^a ; Marie Classon^a ; Patrick Trojer^b ; Peter S. Dragovich^a ; Lesley Murray^a

关键词：Histone demethylase ; KDM5 ; Selective KDM5 inhibitors ; Epigenetics ; Drug resistance ; Lead optimization

刊名：Bioorganic & Medicinal Chemistry Letters

出版年：2016

3.Re: Resistance to Docetaxel in Prostate Cancer is Associated with Androgen Receptor Activation and Loss of KDM5D Expression

作者：Anthony Atala ; MD

刊名：The Journal of Urology

出版年：2017

4.NO_x precursors from biomass pyrolysis: Distribution of amino acids in biomass and Tar-N during devolatilization using model compounds

作者：Hanping Chen ^{hp.chen@163.com" class="auth_mail" title="E-mail the corresponding author} ; Yaohui Si ^{syh850330@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Yingquan Chen ; ^{chenyingquan@hust.edu.cn" class="auth_mail" title="E-mail the corresponding author} ; Haiping Yang ^{yhping2002@163.com" class="auth_mail" title="E-mail the corresponding author} ; Deming Chen ^{chendm512@163.com" class="auth_mail" title="E-mail the corresponding author} ; Wei Chen ^{chenwei_hk@163.com" class="auth_mail" title="E-mail the corresponding author}

关键词：Amino acids ; Nitrogen transformation ; Nitrogen-containing chemical ; Biomass pyrolysis ; NOx precursor

刊名：Fuel

出版年：2017

5.Discovery of KDM5A inhibitors: Homology modeling, virtual screening and structure-activity relationship analysis

作者：Xiaoai Wu^a ; ^b ; ^&dagger ; ; Zhen Fang^a ; ^&dagger ; ; Bo Yang^c ; ^d ; ^&dagger ; ; Lei Zhong^a ; Qiuyuan Yang^a ; Chunhui Zhang^a ; Shenzhen Huang^a ; Rong Xiang^e ; Takayoshi Suzuki^f ; Lin-Li Li^c ; ^{ysylilinli@sina.com" class="auth_mail" title="E-mail the corresponding author} ; Sheng-Yong Yang^a ; ^{yangsy@scu.edu.cn" class="auth_mail" title="E-mail the corresponding author}

关键词：KDM5A ; Histone lysine demethylation ; Structure&ndash ; activity relationship ; Epigenetics ; Small molecule inhibitor

刊名：Bioorganic & Medicinal Chemistry Letters

出版年：2016

6.Design and evaluation of 1,7-naphthyridones as novel KDM5 inhibitors

作者：Sharada S. Labadie^a ; ; Peter S. Dragovich^a ; Richard T. Cummings^b ; Gauri Deshmukh^a ; Amy Gustafson^a ; Ning Han^c ; Jean-Christophe Harmange^b ; James R. Kiefer^a ; Yue Li^c ; Jun Liang^a ; Bianca M. Liederer^a ; Yichin Liu^a ; Wanda Manieri^b ; Wiefeng Mao^c ; Lesley Murray^a ; Daniel F. Ortwine^a ; Patrick Trojer^b ; Erica VanderPorten^a ; Maia Vinogradova^a ; Li Wen^c

关键词：Histone lysine demethylases ; KDM5 inhibitors ; Epigenetics

刊名：Bioorganic & Medicinal Chemistry Letters

出版年：2016

7.Identification of potent, selective KDM5 inhibitors

作者：Victor S. Gehling^a ; ^{victor.gehling@constellationpharma.com" class="auth_mail" title="E-mail the corresponding author} ; Steven F. Bellon^a ; Jean-Christophe Harmange^a ; Yves LeBlanc^a ; Florence Poy^a ; Shobu Odate^a ; Shane Buker^a ; Fei Lan^a ; Shilpi Arora^a ; Kaylyn E. Williamson^a ; Peter Sandy^a ; Richard T. Cummings^a ; Christopher M. Bailey^a ; Louise Bergeron^a ; Weifeng Mao^c ; Amy Gustafson^b ; Yichin Liu^b ; Erica VanderPorten^b ; James E. Audia^a ; Patrick Trojer^a ; Brian K. Albrecht^a

关键词：Histone lysine demethylase ; KDM5 ; JARID1 ; Epigenetics

刊名：Bioorganic & Medicinal Chemistry Letters

出版年：2016

8.H3K4me3 Demethylase Kdm5a Is Required for NK Cell Activation by Associating with p50 to Suppress SOCS1

作者：Dezhi Zhao¹ ; ⁴ ; Qian Zhang² ; ⁴ ; Yiqi Liu¹ ; ⁴ ; Xia Li¹ ; Kai Zhao³ ; Yuanyuan Ding¹ ; Zhiqing Li¹ ; Qicong Shen² ; Chunmei Wang³ ; Nan Li² ; Xuetao Cao¹ ; ² ; ³ ; ^{caoxt@immunol.org" class="auth_mail" title="E-mail the corresponding author}

刊名：Cell Reports

出版年：2016

9.The Histone Demethylase KDM5 Activates Gene Expression by Recognizing Chromatin Context through Its PHD Reader Motif

作者：Xingyin Liu¹ ; Julie Secombe¹ ; ^{julie.secombe@einstein.yu.edu" class="auth_mail" title="E-mail the corresponding author}

关键词：KDM5 ; Lid ; transcription ; PHD motif ; histone ; H3K4me3 ; mitochondria

刊名：Cell Reports

出版年：2015

10.A combinative analysis of gene expression profiles and microRNA expression profiles identifies critical genes and microRNAs in oral lichen planus

作者：Qing Liu^a ; ^{liuqing@fmmu.edu.cn" class="auth_mail" title="E-mail the corresponding author} ; Xinwen Wang^a ; Yuan Liu^b ; Minghui Wei^a ; Lihua Chen^c ; ^{chenlh@fmmu.edu.cn" class="auth_mail" title="E-mail the corresponding author}

关键词：OLP ; oral lichen planus ; DEGs ; differentially expressed genes ; SRGAP2 ; SLITROBO Rho GTPase activating protein 2 ; VAMP4 ; vesicle-associated membrane protein 4 ; LRRTM4 ; leucine rich repeat transmembrane neuronal 4 ; KDM5C ; lysine (K)-specific demethylase5C ; DEMs ; differentially expressed miRNAs ; GSEA ; gene set enrichment analysis ; MSigDB ; molecular signatures database ; PPI ; protein&ndash ; protein interaction ; DCs ; dendritic cells ; DCC ; deleted in colorectal cancer ; AP1 ; adaptor-related protein compl

刊名：Archives of Oral Biology

出版年：2016

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