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Elsevier电子期刊(1579)

在“Elsevier电子期刊”中，命中：1,579条，耗时：0.0129966 秒

在所有数据库中总计命中：1,579条

1.Total coumarins of Hedyotis diffusa induces apoptosis of myelodysplastic syndrome SKM-1 cells by activation of caspases and inhibition of PI3K/Akt pathway proteins

作者：Jianping Jiang^a ; ^b ; ¹ ; Bo Wang^a ; ¹ ; Jing Li^a ; Baodong Ye^a ; Shengyun Lin^a ; ^{lsyww2012@163.com} ; Wenbin Qian^c ; Letian Shan^b ; ^{letian.shan@hotmail.com} ; Thomas Efferth^d

关键词：AIF ; apoptosis-inducing factor ; AML ; acute myeloid leukemia ; CA ; p-coumaric acid ; DMSO ; dimethyl sulfoxide ; ECL ; enhanced chemiluminescence kit ; E-CSME ; E-6-O-p-coumaroyl scandoside methyl ester ; FBS ; fetal bovine serum ; HDW ; Hedyotis diffusa Willd ; HSCT ; hematopoietic stem cell transplantation ; IC50 ; 50% inhibitory concentration ; LSD ; least significant difference ; MAPK ; mitogen-activated protein kinase ; MDS ; myelodysplastic syndromes ; MTT ; 3-(4 ; 5-dimethylthiazol-2-yl)-2 ; 5-diphenyltetrazolium br

刊名：Journal of Ethnopharmacology

出版年：2017

2.Inhibition kinetics and molecular simulation of p-substituted cinnamic acid derivatives on tyrosinase

作者：Yi Cui^a ; Yong-Hua Hu^a ; Feng Yu^a ; Jing Zheng^a ; Lin-Shan Chen^a ; Qing-Xi Chen^a ; ^b ; Qin Wang^a ; ^{qwang@xmu.edu.cn}

关键词：4-CCA ; 4-chlorocinnamic acid ; 4-ECA ; 4-ethoxycinnamic acid ; 4-NCA ; 4-nitrocinnamic acid ; DMSO ; dimethyl-sulfoxide ; L-Tyr ; L-tyrosine ; L-DOPA ; L-3 ; 4-Dihydroxyphenylalanine ; Km ; Michaelis-Menten constant ; KI ; equilibrium constant of the inhibitor combining with the free enzyme ; IC50 ; inhibitor concentration leading to a 50% loss of activity

刊名：International Journal of Biological Macromolecules

出版年：2017

3.A matrix-focused structure-activity and binding site flexibility study of quinolinol inhibitors of botulinum neurotoxin serotype A

作者：William A. Harrell Jr.^a ; ^d ; Rebecca C. Vieira^a ; ^e ; Susan M. Ensel^b ; Vicki Montgomery^a ; Rebecca Guernieri^a ; Vanessa S. Eccard^a ; ^f ; Yvette Campbell^a ; Virginia Roxas-Duncan^a ; ^g ; John H. Cardellina II^a ; ^h ; Robert P. Webb^a ; ^{robert.p.webb6.civ@mail.mil} ; Leonard A. Smith^c

关键词：BoNTs ; botulinum neurotoxins ; BoNT/A ; botulinum neurotoxin serotype A ; HC ; heavy chain ; LC ; light chain ; SNARE ; soluble N-ethylmaleimide-sensitive factor attachment protein receptor ; SNAP-25 ; 25 ; kDa synaptosomal-associated protein ; BIG-IV ; Botulism Immune Globulin Intravenous (Human) ; SAR ; structure-activity relationship ; IC50 ; 50% inhibitory concentration ; MPNHDA ; mouse phrenic nerve hemidiaphragm assay

刊名：Bioorganic & Medicinal Chemistry Letters

出版年：2017

4.Synthesis and characterization of novel, conjugated, fluorescent DNJ derivatives for α-glucosidase recognition

作者：Akihiko Hatano^a ; ^{a-hatano@sic.shibaura-it.ac.jp} ; Yuichi Kanno^a ; Yuya Kondo^a ; Yuta Sunaga^a ; Hatsumi Umezawa^a ; Munehiro Okada^a ; Hideshi Yamada^a ; Ren Iwaki^b ; Atsushi Kato^b ; Koji Fukui^c

关键词：Inhibitor ; α-Glucosidase ; DNJ-fluorescent conjugate ; Docking simulation ; IC50

刊名：Bioorganic & Medicinal Chemistry

出版年：2017

5.Metabolic profile and β-glucuronidase inhibitory property of three species of Swertia

作者：Swagata Karak ; Gargi Nag ; Bratati De ; ^{bdbot@caluniv.ac.in}

关键词：Swertia ; β-Glucuronidase ; Xanthones ; Hepatoprotective

刊名：Revista Brasileira de Farmacognosia

出版年：2017

6.Synthesis, characterization, in vitro SAR and in vivo evaluation of N,N′bisnaphthylmethyl 2-alkyl substituted imidazolium salts against NSCLC

作者：Michael A. DeBord^a ; Marie R. Southerland^a ; Patrick O. Wagers^a ; Kristin M. Tiemann^b ; Nikki K. Robishaw^a ; Kyle T. Whiddon^a ; Michael C. Konopka^a ; Claire A. Tessier^a ; Leah P. Shriver^a ; ^c ; Sailaja Paruchuri^a ; David A. Hunstad^b ; Matthew J. Panzner^a ; ; Wiley J. Youngs^a ; ^{youngs@uakron.edu}

关键词：NCI ; National Cancer Institute ; IC50 ; inhibitory concentration 50% ; NSCLC ; non-small cell lung cancer ; IC23 ; 4 ; 5-dichloro-1 ; 3-bis(naphthalen-2-ylmethyl)imidazolium bromide ; MTT ; 3-(4 ; 5-dimethylthiazol-2-yl)-2 ; 5-diphenyltetrazolium bromide ; CD ; cyclodextrin ; 2-HPβCD ; 2-hydroxypropyl-β-cyclodextrin ; FDA ; Food and Drug Administration ; PS ; phosphatidylserine ; PI ; propidium iodide ; FID ; fluorescent interacalator displacement ; CT-DNA ; calf thymus DNA ; DTP ; Developmental Therapeutics Program ; IP ; intra

刊名：Bioorganic & Medicinal Chemistry Letters

出版年：2017

7.N-Acetyl-chitobiose ameliorates metabolism dysfunction through Erk/p38 MAPK and histone H3 phosphorylation in type 2 diabetes mice

作者：Xia Wu^a ; Jing Wang^b ; Yuqin Shi^b ; Sai Chen^a ; Qiaojuan Yan^a ; Zhengqiang Jiang^b ; ^{zhqjiang@cau.edu.cn} ; Hao Jing^b

关键词：ALX ; alloxan ; COS ; chitooligosaccharide ; Erk ; extracellular signal-regulated kinase ; (GlcNAc)2 ; N-acetyl-chitobiose (PubChem CID ; 160244) ; H&E ; haematoxylin and eosin ; HOMA-IR ; homeostasis model assessment of insulin resistance ; IC50 ; the 50% inhibitory concentration ; IL-1β ; interleukin-1 beta ; JNK ; c-Jun terminal kinase ; MAPK ; mitogen-activated protein kinase ; MDA ; malondialdehyde ; MKK ; MAPK kinases ; MSK ; mitogen and stress activated protein kinase ; NF-κB ; nuclear factor-kappaB ; SOD ; superoxide

刊名：Journal of Functional Foods

出版年：2017

8.Chiral resolution of serial potent and selective σ₁ ligands and biological evaluation of (−)-[¹⁸F]TZ3108 in rodent and the nonhuman primate brain

作者：Xuyi Yue^a ; Hongjun Jin^a ; Zonghua Luo^a ; Hui Liu^a ; Xiang Zhang^a ; Ethan D. McSpadden^b ; Linlin Tian^c ; Hubert P. Flores^c ; Joel S. Perlmutter^a ; ^c ; Stanley M. Parsons^b ; Zhude Tu^a ; ^{tuz@mir.wustl.edu}

关键词：calcd ; calculated ; CH2Cl2 ; dichloromethane ; CNS ; central nervous system ; DMSO ; dimethyl sulfoxide ; [3H]DTG ; [3H]ditolylguanidine ; DTTA ; di-p-toluoyl tartaric acid ; EBP ; emopamil binding protein ; ee ; enantiomeric excess ; EOB ; end of bombardment ; EtOH ; ethanol ; [18F]FTC146 ; 18F-6-(3-fluoropropyl)-3-(2-(azepan-1-yl)ethyl)benzo[d]thiazol-2(3H)-one ; HPLC ; high performance liquid chromatography ; HRMS ; high resolution mass spectrometry ; IC50 ; half maximum inhibitory constant ; K2CO3 ; potassium carbonate

刊名：Bioorganic & Medicinal Chemistry

出版年：2017

9.Efficacy and safety of “Yahom” as a traditional Thai herbal therapy: A systematic review

作者：Krongkarn Chootip^a ; Nathorn Chaiyakunapruk^b ; ^c ; ^d ; ^e ; ^f ; ^h ; Noppamas Soonthornchareonnon^g ; C. Norman Scholfield^b ; ^h ; Anjana Fuangchan^b ; ^{anjanaf@nu.ac.th}

关键词：2-AA ; 2-aminoanthracene ; Ach ; Acetylcholine ; AF2 ; 2-aminofluorene ; Aq ; Aqueous ; BMI ; Body mass index ; BP ; Blood pressure ; BUN ; Blood urea nitrogen ; CYPs ; Cytochromes P450 ; DBP ; Diastolic blood pressure ; DPPH ; 2 ; 2-diphenyl-1-picrylhydrazyl ; ECG ; Electrocardiogram ; FRAP assay ; Ferric reducing antioxidant power assay ; HPLC ; High Performance Liquid Chromatography ; HR ; Heart rate ; IC50 ; Inhibitory concentration that cause 50% inhibition ; ID50 ; Inhibitory dose that cause 50% inhibition ; IP ; Intraperit

刊名：Journal of Ethnopharmacology

出版年：2017

10.Interaction of nonionic detergents with the specific sites of lysozyme amyloidogenic region − inhibition of amyloid fibrillization

作者：Katarina Siposova^a ; ^{katkasiposova@gmail.com} ; ^{siposova@saske.sk} ; Tibor Kozar^b ; Andrey Musatov^a

关键词：CMC ; critical micelle concentration ; DDM ; n-dodecyl-β-d-maltoside ; DH ; hydrodynamic diameter of micelles ; HEWL ; hen egg white lysozyme ; IC50 ; half-maximal inhibitory concentration ; ThT ; thioflavin T ; TX-100 ; Triton X-100

刊名：Colloids and Surfaces B: Biointerfaces

出版年：2017

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