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Elsevier电子期刊(28)

在“Elsevier电子期刊”中，命中：28条，耗时：小于0.01 秒

在所有数据库中总计命中：53条

1.IMI - oral biopharmaceutics tools project - evaluation of bottom-up PBPK prediction success part 1: Characterisation of the OrBiTo database of compounds

作者：Alison Margolskee^a ; ^{alison.margolskee@manchester.ac.uk} ; Adam S. Darwich^a ; Xavier Pepin^b ; ^c ; Shriram M. Pathak^d ; Michael B. Bolger^e ; Leon Aarons^a ; Amin Rostami-Hodjegan^a ; ^d ; Jonas Angstenberger^f ; Franziska Graf^f ; Loic Laplanche^f ; Thomas Mü ; ller^f ; Sara Carlert^g ; Pankaj Daga^h ; Dó ; nal Murphy^b ; Christer Tannergren^g ; Mohammed Yasin^b ; Susanne Greschat-Schadeⁱ ; Wolfgang Mü ; ckⁱ ; Uwe Muensterⁱ ; Dorina van der Meyⁱ ; Kerstin Julia Frank^j ; Richard Lloyd^k ; Lieve Adriaenssen^l ; Jan Bevernage^l ; Loeckie De Zwart^l ; Dominique Swerts^l ; Christophe Tistaert^l ; An Van Den Bergh^l ; Achiel Van Peer^l ; Stefania Beato^m ; Anh-Thu Nguyen-Trung^m ; Joanne Bennettⁿ ; Mark McAllisterⁿ ; Mei Wongⁿ ; Patricia Zane^o ; Cé ; line Ollier^c ; Pascale Vicat^c ; Markus Kolhmann^p ; Alexander Marker^p ; Priscilla Brun^c ; Florent Mazuir^c ; Sté ; phane Beilles^c ; Marta Venczel^p ; Xavier Boulenc^c ; Petra Loos^p ; Hans Lennernä ; s^q ; Bertil Abrahamsson^g

关键词：API ; active pharmaceutical ingredient ; AUC ; area under the curve ; BCS ; biopharmaceutics classification system ; BP ; blood-to-plasma ratio ; Cmax ; maximum concentration ; CL ; clearance ; Do ; dose number according to BCS ; DDI ; drug-drug interaction ; EFPIA ; European Federation of Pharmaceutical Industries and Associations ; Foral ; absolute oral bioavailability ; Frel ; relative bioavailability ; fup ; fraction unbound in plasma ; IMI ; Innovative Medicines Initiative ; LogP ; logarithm of the octanol/water part

刊名：European Journal of Pharmaceutical Sciences

出版年：2017

2.Development of a μDissolution-Permeation model with in situ drug concentration monitoring

作者：Ragna Berthelsen^a ; Julie Pelle Byrialsen^a ; René ; Holm^b ; Jette Jacobsen^a ; Bertil Abrahamsson^c ; Lasse Saabye^d ; Peter Madelung^a ; Anette Mü ; llertz^a ; ^d ; ^{Anette.mullertz@sund.ku.dk" class="auth_mail" title="E-mail the corresponding author}

关键词：Dissolution-permeation model ; In vitro ; Caco-2 cells ; In situ drug concentrations monitoring

刊名：Journal of Drug Delivery Science and Technology

出版年：2016

3.Effect of food intake and co-administration of placebo self-nanoemulsifying drug delivery systems on the absorption of cinnarizine in healthy human volunteers

作者：Martin Lau Christiansen^a ; ^{martinlauchristiansen@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Rene Holm^a ; ^b ; Bertil Abrahamsson^d ; Jette Jacobsen^a ; Jakob Kristensen^c ; Jens Rikardt Andersen^f ; Anette Mü ; llertz^a ; ^e

关键词：SNEDDS ; Food effect ; Low soluble compounds ; Humans ; Enabling formulations ; Oral absorption ; Cinnarizine

刊名：European Journal of Pharmaceutical Sciences

出版年：2016

4.Validation of the IntelliCap庐 system as a tool to evaluate extended release profiles in human GI tract using metoprolol as model drug

作者：Erik Sö ; derlind^a ; Bertil Abrahamsson^a ; Fredrik Erlandsson^a ; Christoph Wanke^b ; Ventzeslav Iordanov^b ; Christian von Corswant^a ; ^{christian.von.corswant@astrazeneca.com" class="auth_mail" title="E-mail the corresponding author}

关键词：Metoprolol ; IntelliCap® ; system ; Electronic drug delivery ; Regional absorption ; Human study ; In-vitro-in-vivo-correlation

刊名：Journal of Controlled Release

出版年：2015

5.Evaluation of the use of Classical Nucleation Theory for predicting intestinal crystalline precipitation of two weakly basic BSC class II drugs

作者：Sara Carlert ; Hans Lennern盲s ; Bertil Abrahamsson

关键词：Precipitation ; In silico prediction ; Absorption ; Crystallization ; Classical Nucleation Theory ; In vitro&ndash ; in vivo correlations

刊名：European Journal of Pharmaceutical Sciences

出版年：12 March, 2014

6.Evaluation of an in vitro faecal degradation method for early assessment of the impact of colonic degradation on colonic absorption in humans

作者：Christer Tannergren¹ ; Anders Borde ; ¹ ; ^{Anders.Borde@AstraZeneca.com" class="auth_mail} ; Cecilia Boreström ; Bertil Abrahamsson ; Anders Lindahl

关键词：Colon ; Absorption ; Degradation kinetics ; Permeability ; Extended release

刊名：European Journal of Pharmaceutical Sciences

出版年：16 June 2014

7.Cinnarizine food-effects in beagle dogs can be avoided by administration in a Self Nano Emulsifying Drug Delivery System (SNEDDS)

作者：Martin Lau Christiansen^a ; Rene Holm^a ; ^b ; Jakob Kristensen^c ; Mads Kreilgaard^a ; Jette Jacobsen^a ; Bertil Abrahamsson^d ; Anette Mü ; llertz^a ; ^e ; ^{anette.mullertz@sund.ku.dk" class="auth_mail}

关键词：SNEDDS ; Food interaction ; Low soluble compounds ; Dogs ; Enabling formulations

刊名：European Journal of Pharmaceutical Sciences

出版年：16 June 2014

8.Fed and fasted state gastro-intestinal in vitro lipolysis: In vitro in vivo relations of a conventional tablet, a SNEDDS and a solidified SNEDDS

作者：Philip Carsten Christophersen^a ; Martin Lau Christiansen^a ; Rene Holm^a ; ^b ; Jakob Kristensen^c ; Jette Jacobsen^a ; Bertil Abrahamsson^d ; Anette Mü ; llertz^a ; ^e ; ^{anette.mullertz@sund.ku.dk" class="auth_mail}

关键词：Lipid-based drug delivery systems ; IVIVC ; Lipid hydrolysis ; Food interaction ; SNEDDS ; Low-soluble compounds

刊名：European Journal of Pharmaceutical Sciences

出版年：16 June 2014

9.In vitro models for the prediction of in vivo performance of oral dosage forms

作者：Edmund S. Kostewicz^a ; Bertil Abrahamsson^b ; Marcus Brewster^c ; Joachim Brouwers^d ; James Butler^e ; Sara Carlert^b ; Paul A. Dickinson^f ; Jennifer Dressman^a ; René ; Holm^g ; Sandra Klein^h ; James Mannⁱ ; Mark McAllister^j ; Mans Minekus^k ; Uwe Muenster^l ; Anette Mü ; llertz^m ; Miriam Verwei^k ; Maria Vertzoniⁿ ; Werner Weitschies^h ; Patrick Augustijns^d ; ^{patrick.augustijns@pharm.kuleuven.be" class="auth_mail}

关键词：BCS ; biopharmaceutics classification system ; ER ; extended release ; IR ; immediate release ; IMI ; innovative medicines initiative ; IVIVC ; in vitro in vivo Correlation ; MR ; modified release ; OrBiTo ; oral biopharmaceutical tools ; PK ; pharmacokinetics ; PBPK ; physiologically-based pharmacokinetics ; QbD ; quality by design ; QC ; quality control ; FDA ; U.S Food and Drug Administration ; USP ; United States Pharmacopeia

刊名：European Journal of Pharmaceutical Sciences

出版年：16 June 2014

10.In vivo methods for drug absorption - Comparative physiologies, model selection, correlations with in vitro methods (IVIVC), and applications for formulation/API/excipient characterization including food effects

作者：Erik Sjö ; gren^a ; Bertil Abrahamsson^b ; Patrick Augustijns^c ; Dieter Becker^d ; Michael B. Bolger^e ; Marcus Brewster^f ; Joachim Brouwers^c ; Talia Flanagan^g ; Matthew Harwood^h ; Christian Heinenⁱ ; René ; Holm^j ; Hans-Paul Juretschke^k ; Marlies Kubbingaⁱ ; ^l ; Anders Lindahl^m ; Viera Lukacova^e ; Uwe Mü ; nsterⁿ ; Sibylle Neuhoff^h ; Mai Anh Nguyenⁱ ; Achiel van Peer^f ; Christos Reppas^o ; Amin Rostami Hodjegan^p ; Christer Tannergren^b ; Werner Weitschies^q ; Clive Wilson^r ; Patricia Zane^s ; Hans Lennernä ; s^a ; Peter Langguthⁱ ; ^{langguth@uni-mainz.de" class="auth_mail}

关键词：ABC ; ATP-Binding Cassette ; An ; absorption number ; API ; active pharmaceutical ingredient ; AUC ; area under the curve ; BCRP ; breast cancer resistant protein ; BCS ; biopharmaceutic classification system ; BDDCS ; biopharmaceutics drug disposition drug classification system ; BE ; bioequivalence ; CYP ; cytochrome P450 ; D0 ; dose number ; Dn ; dissolution number ; DDI ; drug&ndash ; drug interactions ; DSC ; differential scanning calorimetry ; EMA ; European Medicines Agency ; fabs ; fraction of dose absorbed ; FaSSIF ; F

刊名：European Journal of Pharmaceutical Sciences

出版年：16 June 2014

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