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Elsevier电子期刊(20)

在“Elsevier电子期刊”中，命中：20条，耗时：0.0669682 秒

在所有数据库中总计命中：28条

1.Structure-activity relationship study of a small cyclic peptide H-c[Lys-Pro-Glu]-Arg-OH: a potent inhibitor of Vascular Endothelial Growth Factor interaction with Neuropilin-1

作者：Karolina Grabowska^a ; Anna K. Puszko^a ; Piotr F.J. Lipiński^b ; Anna K. Laskowska^b ; Beata Wileńska^a ; Ewa Witkowska^a ; Gerard Y. Perret^c ; Aleksandra Misicka^a ; ^b ; ^{misicka@chem.uw.edu.pl}

关键词：ABTS ; 2 ; 2&prime ; -azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) diammonium salt ; ACN ; acetonitrile ; BSA ; bovine serum albumin ; (bt)-VEGF165 ; biotinylated-VEGF165 ; 6-Cl-HOBt ; 6-chloro-1-hydroxybenzotriazole dihydrate ; DIPEA ; N ; N-diisopropylethylamine ; DMEM ; Dulbecco&rsquo ; s Modified Eagle Medium ; EGM ; Endothelial Cell Growth Media ; ELISA ; enzyme-linked immunosorbent assay ; FA ; formic acid ; MDA-MB-231 ; human breast adenocarcinoma cells ; MTS ; 3-(4 ; 5-dimethylthiazol-2-yl)-5-(3-carboxymethoxypheny

刊名：Bioorganic & Medicinal Chemistry

出版年：2017

2.Synthesis of linear and cyclic peptide-PEG-lipids for stabilization and targeting of cationic liposome-DNA complexes

作者：Kai K. Ewert^a ; ^b ; ^c ; ^{ewert@mrl.ucsb.edu" class="auth_mail" title="E-mail the corresponding author} ; Venkata Ramana Kotamraju^d ; Ramsey N. Majzoub^a ; ^b ; ^c ; ^&dagger ; ; Victoria M. Steffes^a ; ^b ; ^c ; ^e ; Emily A. Wonder^a ; ^b ; ^c ; Tambet Teesalu^d ; ^f ; ^g ; Erkki Ruoslahti^d ; ^f ; Cyrus R. Safinya^a ; ^b ; ^c ; ^{safinya@mrl.ucsb.edu" class="auth_mail" title="E-mail the corresponding author}

关键词：CL ; cationic liposome ; DIEA ; N ; N-diisopropylethylamine ; DMEM ; Dulbecco&rsquo ; s modified Eagle&rsquo ; s medium ; DOB ; 3 ; 4-dioleyloxybenzoic acid ; DOPC ; 1 ; 2-dioleoyl-sn-glycerophosphatidylcholine ; DOTAP ; 2 ; 3-dioleyloxypropyltrimethylammonium chloride ; EMCA ; 6-maleimidohexanoic acid ; HOBt ; 1-hydroxybenzotriazole hydrate ; HOPfp ; pentafluorophenol ; NA ; nucleic acid ; PBS ; phosphate-buffered saline ; PEG ; poly(ethylene glycol) ; siRNA ; short interfering RNA ; TBTU ; O-benzotriazol-1-yl-NN ; N&prime ; N&prime-

刊名：Bioorganic & Medicinal Chemistry Letters

出版年：2016

3.In vivo effective dibenzo[b,d]furan-1-yl-thiazoles as novel PDE-4 inhibitors

作者：Gopalan Balasubramanian^a ; Sukunath Narayanan^a ; Lavanya Andiappan^a ; Thirunavukkarasu Sappanimuthu^a ; Saravanan Thirunavukkarasu^a ; Shamundeeswari Sundaram^a ; Saravanakumar Natarajan^a ; Naresh Sivaraman^a ; Sridharan Rajagopal^a ; Fakrudeen Ali Ahamed Nazumudeen^b ; Sanjeev Saxena^b ; Santosh L. Vishwakarma^b ; Shridhar Narayanan^b ; Ganapavarapu V.R. Sharma^a ; Chidambaram V. Srinivasan^a ; Narasimhan Kilambi^a ; ^{narasimhank@orchidpharma.com" class="auth_mail" title="E-mail the corresponding author} ; ^{k_narasimhan99@yahoo.com" class="auth_mail" title="E-mail the corresponding author} ; ^{ipm@orchidpharma.com" class="auth_mail" title="E-mail the corresponding author}

关键词：PDE ; phosphodiesterase ; TNF-α ; tumour necrosis factor ; nm ; nanomolar ; IL ; interleukin ; μM ; micromolar ; @ ; at ; PBMC ; peripheral blood mononuclear cells ; LPS ; lipopolysaccharides ; COPD ; chronic obstructive pulmonary disease ; CC ; column chromatography ; HCl ; hydrochloric acid ; h ; hour ; rt ; room temperature ; mp ; melting point ; ND ; not done ; cpm ; counts per minute ; CHCl3 ; chloroform ; MDC/CH2Cl2 ; methylene dichloride ; MeOH ; methanol ; EtOAc ; ethylacetate ; HOBt ; hydroxybenzotriazole ; DMAP ; dimethylaminop

刊名：Bioorganic & Medicinal Chemistry

出版年：2016

4.Solid-phase synthesis of libraries of ethynylated aminosteroid derivatives as potential antileukemic agents

作者：Amé ; lie Talbot ; René ; Maltais ; Lucie Carolle Kenmogne ; Jenny Roy ; Donald Poirier ; ^{donald.poirier@crchul.ulaval.ca" class="auth_mail" title="E-mail the corresponding author}

关键词：AA ; amino acid ; AcOH ; acetic acid ; 6-Cl-HOBt ; 6-chloro-1-hydroxybenzotriazole ; DCM ; dichloromethane ; DIPEA ; N ; N-diisopropylethylamine ; DMF ; N ; N-dimethylformamide ; Fmoc ; 9-fluorenylmethoxycarbonyl ; h ; hour ; HOBt ; 1-hydroxybenzotriazole hydrate ; HPLC ; high-performance liquid chromatography ; IR ; infrared spectroscopy ; MS ; mass spectrometry ; NMR ; nuclear magnetic resonance ; Pal ; pyridylalanine ; Phe ; phenylalanine ; Pro ; proline ; PS-DES ; polystyrene diethylsilyl resin ; PyBOP ; (benzotriazol-1-yloxy)tri

刊名：Steroids

出版年：2016

5.Poly(α-hydroxy acid)s and poly(α-hydroxy acid-co-α-amino acid)s derived from amino acid

作者：Arijit Basu ; Konda Reddy Kunduru ; Joshua Katzhendler ; Abraham J. Domb ; ^{avid@ekmd.huji.ac.il}

关键词：COCl2 ; phosgene ; EDC ; N-(3-dimethylaminopropyl)-N&prime ; -ethylcarbodiimide hydrochloride ; NHS ; N-hydroxysuccinimide ; DCC ; N ; N&prime ; -dicyclohexylcarbodiimide ; HOBt ; hydroxybenzotriazole ; PTSA ; 4-toluenesulfonic acid/p-toluenesulfonic acid ; PEA ; poly(esteramide) ; HOTf ; trifluoromethanesulfonic acid ; MeOTf ; methyl trifluoromethanesulfonate ; DMAP ; 4-dimethylaminopyridine ; Sn(Oct)2 ; Tin(II) 2-ethylhexanoate ; Al(OR)3 ; aluminum alkoxides ; Ti(OR)4 ; titanium alkoxide ; OCA ; O-carboxyanhydride ; NCA ; N-car

刊名：Advanced Drug Delivery Reviews

出版年：2016

6.Synthesis, biological studies and molecular dynamics of new anticancer RGD-based peptide conjugates for targeted drug delivery

作者：Y. Gilad^a ; ^b ; E. Noy^c ; H. Senderowitz^c ; A. Albeck^b ; M.A. Firer^d ; G. Gellerman^a ; ^{garyg@ariel.ac.il" class="auth_mail" title="E-mail the corresponding author}

关键词：ACN ; acetonitrille ; Cl-Trt ; 2-chlorotritylchloride ; DCM ; dichloromethane ; DIPA ; diisopropylethylamine ; DMAP ; 4-(N ; N-dimethylamino)pyridine ; DMBA ; dimethyl barbituric acid ; DMF ; N ; N-dimethylformamide ; DMSO ; dimethyl sulfoxide ; EDC ; N-(3-dimethylaminopropyl)-N&prime ; -ethylcarbodiimide hydrochloride ; Fmoc ; 9-fluorenylmethoxycarbonyl ; HOBT ; hydroxybenzotriazole ; HPLC ; high-pressure liquid chromatography ; LH ; liver homogenate ; MALDI ; matrix-assisted laser desorption/ionization ; NMR ; nuclear magnetic

刊名：Bioorganic & Medicinal Chemistry

出版年：2016

7.Design, synthesis and in vitro biological evaluation of a small cyclic peptide as inhibitor of vascular endothelial growth factor binding to neuropilin-1

作者：Karolina Grabowska^a ; Anna K. Puszko^a ; Piotr F.J. Lipiński^b ; Anna K. Laskowska^b ; Beata Wileńska^a ; Ewa Witkowska^a ; Aleksandra Misicka^a ;

关键词：ABTS ; 2 ; 2&prime ; -azino-bis(3-ethylbenzothiazoline-6-sulfonic acid)diammonium salt ; BSA ; bovine serum albumin ; (bt)-VEGF165 ; biotinylated-VEGF165 ; 6-Cl· ; HOBt ; 6-chloro-1-hydroxybenzotriazole dehydrate ; DIPEA ; N ; N-diisopropylethylamine ; ELISA ; enzyme-linked immunosorbent assay ; HUVEC ; Human Umbilical Vein Endothelial Cells ; MDA-MB-231 ; human breast adenocarcinoma cells ; MTS ; 3-(4 ; 5-dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-sulfophenyl)-2H-tetrazolium salt ; PBS ; phosphate buffered

刊名：Bioorganic & Medicinal Chemistry Letters

出版年：2016

8.Discovery of potent, selective, and orally bioavailable inhibitors of interleukin-1 receptor-associate kinase-4

作者：Zhulun Wang ; ^{zwang@amgen.com" class="auth_mail" title="E-mail the corresponding author} ; Daqing Sun ; ^{daqingsun@yahoo.com" class="auth_mail" title="E-mail the corresponding author} ; Sheree Johnstone ; Zhaodan Cao ; Xiong Gao ; Juan C. Jaen ; Jingqian Liu ; Sarah Lively ; Shichang Miao ; Athena Sudom ; Craig Tomooka ; Nigel P.C. Walker ; Matthew Wright ; Xuelei Yan ; Qiuping Ye ; Jay P. Powers

关键词：MeCN ; acetonitrile ; CL ; clearance ; Dess&ndash ; Martin periodinane ; 11 ; 1-tris(acetyloxy)-1 ; 1-dihydro-1 ; 2-benziodoxol-3-(1H)-one ; DIBALH ; diisobutylaluminum hydride ; DMF ; N ; N-dimethylformamide ; EtOAc ; ethyl acetate ; HBTU ; NN ; N&prime ; N&prime ; -tetramethyl-O-(1H-benzotriazol-1-yl)uronium hexafluorophosphate ; HOBT ; hydroxybenzotriazole ; NMM ; N-methylmorpholine ; THF ; tetrahydrofuran

刊名：Bioorganic & Medicinal Chemistry Letters

出版年：2015

9.N-terminal guanidinylation of TIPP (Tyr-Tic-Phe-Phe) peptides results in major changes of the opioid activity profile

作者：Grazyna Weltrowska ; Thi M.-D. Nguyen ; Nga N. Chung ; Brian C. Wilkes ; Peter W. Schiller

关键词：BBB ; blood&ndash ; brain barrier ; Boc ; tert-butyloxycarbonyl ; Cl-HOBt ; 6-chloro-1-hydroxybenzotriazole ; DAMGO ; H-Tyr-D-Ala-Gly-Phe(NMe)-Gly-ol ; DIC ; 1 ; 3-diisopropylcarbodiimide ; DIPP ; H-Dmt-Tic-Phe-Phe-OH ; DIPP-NH2 ; H-Dmt-Tic-Phe-Phe-NH2 ; DIPP-NH2[¦·] ; H-Dm

刊名：Bioorganic and Medicinal Chemistry Letters

出版年：2013

10.Design, synthesis, and biological activities of novel hexahydropyrazino[1,2-a]indole derivatives as potent inhibitors of apoptosis (IAP) proteins antagonists with improved membrane permeability across MDR1 expressing cells

作者：Zenyu Shiokawa ; Kentaro Hashimoto ; Bunnai Saito ; Yuya Oguro ; Hiroyuki Sumi ; Masato Yabuki ; Mie Yoshimatsu ; Yohei Kosugi ; Yasuyuki Debori ; Nao Morishita ; Douglas R. Dougan ; Gyorgy P. Snell ; Sei Yoshida ; Tomoyasu Ishikawa

关键词：HATU ; O-(7-azabenzotriazol-1-yl)-NN ; N&prime ; N&prime ; -tetramethyluronium hexafluorophosphate ; DIPEA ; N-ethyldiisopropylamine ; Ac ; acetyl ; CDCl3 ; deuteratedchloroform ; DMF ; N ; N-dimethylformamide ; DMSO ; dimethyl sulfoxide ; DMT-MM ; 4-(4 ; 6-dimethoxy-13 ; 5-triazin-2-yl)-4-methylmorpholinium chloride ; EDC ; 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide ; Et ; ethyl ; HOBT ; 1-hydroxybenzotriazole ; i ; iso ; mp ; melting point ; Me ; methyl ; Pd/C ; palladium on carbon ; Pd(OH)2/C ; palladium hydroxide on carbon ; P

刊名：Bioorganic and Medicinal Chemistry

出版年：15 December, 2013

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