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Elsevier电子期刊(283)

在“Elsevier电子期刊”中，命中：283条，耗时：0.0579727 秒

在所有数据库中总计命中：355条

1.DNA-PKcs: A promising therapeutic target in human hepatocellular carcinoma?

作者：Rosa M. Pascale^a ; ¹ ; Christy Joseph^b ; ¹ ; Gavinella Latte^a ; Matthias Evert^c ; Francesco Feo^a ; Diego F. Calvisi^a ; ^b ; ^{calvisid@uniss.it" class="auth_mail" title="E-mail the corresponding author}

关键词：CHIP ; chromatin immunoprecipitation ; DNA-PKcs ; DNA dependent protein kinase catalytic subunit ; DSBs ; double strand breaks ; GI ; genomic instability ; HCC ; hepatocellular carcinoma ; NHEJ ; non-homologous end-joining

刊名：DNA Repair

出版年：2016

2.Lovastatin prevents cisplatin-induced activation of pro-apoptotic DNA damage response (DDR) of renal tubular epithelial cells

作者：Katharina Krü ; ger^a ; Verena Ziegler^a ; Christina Hartmann^a ; Christian Henninger^a ; Jü ; rgen Thomale^b ; Nicole Schupp^a ; Gerhard Fritz^a ; ^{fritz@uni-duesseldorf.de" class="auth_mail" title="E-mail the corresponding author}

关键词：ApG ; adenine-guanine ; ATM ; ataxia telangiectasia mutated ; ATR ; ataxia telangiectasia and Rad3 related kinase ; Bax ; Bcl2-associated X protein ; Bcl2 ; B-cell/lymphoma 2 ; Chk1 ; checkpoint kinase 1 ; Chk2 ; checkpoint kinase 2 ; CisPt ; cisplatin ; Ctr1 ; solute carrier family 31 (copper transporter) ; member 1 (SLC31A1) ; Csb ; Cockayne syndrome group B ; DAPI ; 4&prime ; 6-diamidino-2-phenylindole ; DDR ; DNA damage response ; DSBs ; DNA double-strand breaks ; DNA-PKcs ; catalytic subunit of the DNA-dependent protei

刊名：Toxicology and Applied Pharmacology

出版年：2016

3.A novel small molecule inhibitor of the DNA repair protein Ku70/80

作者：Eric Weterings^a ; ¹ ; ^{eweterings@email.arizona.edu" class="auth_mail" title="E-mail the corresponding author} ; Alfred C. Gallegos^a ; Lauren N. Dominick^a ; Laurence S. Cooke^b ; Trace N. Bartels^a ; Josef Vagner^c ; Terry O. Matsunaga^d ; Daruka Mahadevan^b ; ¹

关键词：DNA-PKCS ; DNA-dependent protein kinase catalytic subunit ; DSB DNA ; double strand break ; EMSA ; electrophoretic mobility shift assay ; GBM ; glioblastoma multiforme ; NHEJ ; non-homologous end-joining ; PrEC ; prostate epithelial cells ; RT ; radiation therapy

刊名：DNA Repair

出版年：2016

4.Lovastatin protects keratinocytes from DNA damage-related pro-apoptotic stress responses stimulated by anticancer therapeutics

作者：Verena Ziegler¹ ; Anne Albers¹ ; Gerhard Fritz ; ^{fritz@uni-duesseldorf.de" class="auth_mail" title="E-mail the corresponding author}

关键词：53BP1 ; tumor suppressor p53 binding protein 1 ; ATM ; ataxia telangiectasia mutated ; ATR ; ataxia telangiectasia and Rad3-related ; Chk ; checkpoint kinase ; DSB ; DNA double-strand break ; DDR ; DNA damage response ; DNA-PKcs ; DNA-dependent protein kinase ; catalytic subunit ; Doxo ; doxorubicin ; 5-FU ; 5-fluorouracil ; γH2AX ; Ser139 phosphorylated histone H2AX ; HU ; hydroxyurea ; IR ; ionizing radiation ; JNK ; c-Jun N-terminal kinase ; Kap1 ; KRAB-associated protein 1 ; Lova ; HMG-CoA-reductase inhibitor lovastatin

刊名：Biochimica et Biophysica Acta (BBA)-Molecular Cell Research

出版年：2016

5.T0070907 inhibits repair of radiation-induced DNA damage by targeting RAD51

作者：Zhengzhe An^a ; Jae-Ran Yu^b ; Woo-Yoon Park^a ; ^{wynpark@chungbuk.ac.kr" class="auth_mail" title="E-mail the corresponding author}

关键词：DNA-PK ; DNA-dependent protein kinase ; DNA-PKcs ; DNA-dependent protein kinase catalytic subunit ; DSB ; double-strand break ; FBS ; foetal bovine serum ; HR ; homologous recombination ; IR ; ionising radiation ; NHEJ ; non-homologous end joining ; PPARγ ; peroxisome proliferator-activated receptor gamma ; RT ; radiation therapy ; T007 ; T0070907 ; TBST ; Tris-buffered saline and Tween 20

刊名：Toxicology in Vitro

出版年：2016

6.Synergistic potentiation of (−)-lomaiviticin A cytotoxicity by the ATR inhibitor VE-821

作者：Laureen C. Colis^a ; Seth B. Herzon^a ; ^b ; ^{seth.herzon@yale.edu" class="auth_mail" title="E-mail the corresponding author}

关键词：ATR ; ataxia telangiectasia and Rad3-related protein ; SSB ; single-strand break ; DSB ; double-strand break ; PI3KK ; phosphatidylinositol 3-kinase-related kinase ; ATM ; ataxia telangiectasia mutated ; DNA-PKcs ; DNA-dependent protein kinase catalytic subunit ; BRCA2 ; breast cancer type 2 ; PTEN ; phosphatase and tensin homolog ; KU80 ; Ku autoantigen protein p80 ; NHEJ ; non-homologous end joining ; HR ; homologous recombination ; IR ; ionizing radiation ; PARP-1 ; poly(ADP-ribose) polymerase-1 ; PARP-2 ; poly(ADP-rib

刊名：Bioorganic & Medicinal Chemistry Letters

出版年：2016

7.The role of gene mutations and gene products in intestinal tissue reactions from ionising radiation

作者：Jolyon H. Hendry^a ; ^{jhendry2002uk@yahoo.com} ; Kensuke Otsuka^b

关键词：Ascl2 ; achaete-scute family bHLH transcription factor 2 ; ASM ; ase acid sphingomyelinase ; ATM ; ataxia telangiectasia mutated ; Bak1 ; Bcl2 antagonist/killer 1 ; Bax ; Bcl2 associated X ; Bcl-2 ; B-cell lymphoma 2 ; bFGF ; basic fibroblast growth factor ; Bmi1 ; B lymphoma Mo-MLV insertion region 1 homolog ; BMP ; bone morphogenetic protein ; BMT ; bone marrow transplants ; CBC ; crypt base columnar ; DLL1 ; delta-like 1 ; DNA-PKcs ; DNA-dependent protein kinase catalytic subunit ; EGF ; epidermal growth factor ; FGF ; f

刊名：Mutation Research/Reviews in Mutation Research

出版年：2016

8.Novel non-peptide small molecules preventing IKKβ/NEMO association inhibit NF-κB activation in LPS-stimulated J774 macrophages

作者：Francesca De Falco¹ ; Carmen Di Giovanni¹ ; Carmen Cerchia ; Daniela De Stefano² ; Antonella Capuozzo ; Carlo Irace ; Teresa Iuvone ; Rita Santamaria ; Rosa Carnuccio ; ^{rosa.carnuccio@unina.it" class="auth_mail" title="E-mail the corresponding author} ; Antonio Lavecchia ; ^{antonio.lavecchia@unina.it" class="auth_mail" title="E-mail the corresponding author}

关键词：ADME ; absorption ; distribution ; metabolism ; and excretion ; DMEM ; Dulbecco&rsquo ; s modified Eagle&rsquo ; s medium ; DMSO ; dimethyl sulfoxide ; EMSA ; Electrophoretic Mobility Shift Assay ; Erk ; extracellular-signal-related kinase ; FBS ; foetal bovine serum ; GAPDH ; glyceraldehyde-3-phosphate dehydrogenase ; Glide SP ; Glide Single Precision ; Glide XP ; Glide extra precision ; H-bonds ; hydrogen bonds ; HTVS ; high-throughput virtual screening ; IKK ; IκB kinase ; iNOS ; inducible nitric-oxide synthase ; J774 macrop

刊名：Biochemical Pharmacology

出版年：2016

9.Versatility in phospho-dependent molecular recognition of the XRCC1 and XRCC4 DNA-damage scaffolds by aprataxin-family FHA domains

作者：Amy L. Cherry^a ; ¹ ; Timothy J. Nott^a ; ² ; Geoffrey Kelly^b ; Stuart L. Rulten^b ; Keith W. Caldecott^b ; Stephen J. Smerdon^a ; ^{Steve.Smerdon@crick.ac.uk" class="auth_mail" title="E-mail the corresponding author}

关键词：APLF ; aprataxin- and PNK-like factor ; PNKP ; polynucleotide kinase phosphatase ; FHA ; forkhead-associated ; XRCC1 ; X-ray repair cross-complementing protein 1 ; XRCC4 ; X-ray repair cross-complementing protein 4 ; PARP-1 ; poly(ADP-ribose)polymerase 1 ; NHEJ ; non-homologous end-joining ; DNA-PKcs ; catalytic subunit of DNA-dependent protein kinase ; CK2 ; casein kinase 2 ; HIT ; Histidine triad ; ZF ; zinc finger ; NTD ; N-terminal domain ; BRCT ; BRCA1 C-terminal ; CC ; coiled-coil ; ITC ; isothermal titration calorime

刊名：DNA Repair

出版年：2015

10.ATR signaling cooperates with ATM in the mechanism of low dose hypersensitivity induced by carbon ion beam

作者：Lian Xue^a ; ^b ; Yoshiya Furusawa^c ; Dong Yu^d ; ^{yudong@suda.edu.com" class="auth_mail" title="E-mail the corresponding author}

关键词：IR ; ionizing radiation ; LET ; linear energy transfer ; HRS ; hyper-radiosensitivity ; IRR ; induced radioresistance ; DSB ; DNA double strand break ; ATM ; ataxia telangiectasia mutated homolog ; ATR ; ataxia telangiectasia and Rad3 related ; DNA-PKcs ; DNA-dependent protein kinase catalytic subunit ; CHK1 ; checkpoint kinase 1 ; ssDNA ; single strand DNA ; RPA ; replication protein A ; NHEJ ; non-homologous end-joining ; HR ; homologous recombination

刊名：DNA Repair

出版年：2015

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