作者：Kathrin Klein¹ ; Roman Tremmel¹ ; Sarah Fehr² ; Stefan Winter¹ ; Elke Schaeffeler¹ ; Matthias Schwab¹ ; Saskia Biskup² ; Ulrich M. Zanger¹

刊名：Drug Metabolism and Pharmacokinetics

出版年：2017

作者：Matthias Schwab

刊名：Drug Metabolism and Pharmacokinetics

出版年：2017

作者：Barbara C. Worst^a ; ^b ; ^c ; ¹ ; ^{b.worst@dkfz-heidelberg.de" class="auth_mail" title="E-mail the corresponding author} ; Cornelis M. van Tilburg^b ; ^c ; ^d ; ^e ; ¹ ; ^{cornelis.vantilburg@nct-heidelberg.de" class="auth_mail" title="E-mail the corresponding author} ; Gnana Prakash Balasubramanian^c ; ^f ; ^g ; ¹ ; ^{g.balasubramanian@dkfz-heidelberg.de" class="auth_mail" title="E-mail the corresponding author} ; Petra Fiesel^c ; ^h ; ⁱ ; ¹ ; ^{Petra.Fiesel@med.uni-heidelberg.de" class="auth_mail" title="E-mail the corresponding author} ; Ruth Witt^d ; ^{ruth.witt@nct-heidelberg.de" class="auth_mail" title="E-mail the corresponding author} ; Angelika Freitag^d ; ^{angelika.freitag@nct-heidelberg.de" class="auth_mail" title="E-mail the corresponding author} ; Miream Boudalil^c ; ^h ; ⁱ ; ^{Miream.Boudalil@med.uni-heidelberg.de" class="auth_mail" title="E-mail the corresponding author} ; Christopher Previti^j ; ^{christopher.previti@Dkfz-Heidelberg.de" class="auth_mail" title="E-mail the corresponding author} ; Stephan Wolf^j ; ^{s.wolf@dkfz-heidelberg.de" class="auth_mail" title="E-mail the corresponding author} ; Sabine Schmidt^j ; ^{sabine.schmidt@dkfz-heidelberg.de" class="auth_mail" title="E-mail the corresponding author} ; Sasithorn Chotewutmontri^j ; ^{s.chotewutmontri@Dkfz-Heidelberg.de" class="auth_mail" title="E-mail the corresponding author} ; Melanie Bewerunge-Hudler^j ; ^{M.Hudler@dkfz-heidelberg.de" class="auth_mail" title="E-mail the corresponding author} ; Matthias Schick^j ; ^{m.schick@Dkfz-Heidelberg.de" class="auth_mail" title="E-mail the corresponding author} ; Matthias Schlesner^c ; ^k ; ^{m.schlesner@Dkfz-Heidelberg.de" class="auth_mail" title="E-mail the corresponding author} ; Barbara Hutter^c ; ^f ; ^g ; ^{b.hutter@dkfz-heidelberg.de" class="auth_mail" title="E-mail the corresponding author} ; Lenka Taylor^l ; ^{Lenka.Taylor@med.uni-heidelberg.de" class="auth_mail" title="E-mail the corresponding author} ; Tobias Borst^m ; ^{Tobias.Borst@uk-erlangen.de" class="auth_mail" title="E-mail the corresponding author} ; Christian Sutterⁿ ; ^{C.Sutter@med.uni-heidelberg.de" class="auth_mail" title="E-mail the corresponding author} ; Claus R. Bartramⁿ ; ^{cr_bartram@med.uni-heidelberg.de" class="auth_mail" title="E-mail the corresponding author} ; Till Milde^b ; ^c ; ^e ; ^{t.milde@dkfz-heidelberg.de" class="auth_mail" title="E-mail the corresponding author} ; Elke Pfaff^a ; ^b ; ^c ; ^{e.pfaff@dkfz-heidelberg.de" class="auth_mail" title="E-mail the corresponding author} ; Andreas E. Kulozik^b ; ^{andreas.kulozik@med.uni-heidelberg.de" class="auth_mail" title="E-mail the corresponding author} ; Arend von Stackelberg^o ; ^{Arend.Stackelberg@charite.de" class="auth_mail" title="E-mail the corresponding author} ; Roland Meisel^p ; ^{Meisel@med.uni-duesseldorf.de" class="auth_mail" title="E-mail the corresponding author} ; Arndt Borkhardt^p ; ^{Arndt.Borkhardt@med.uni-duesseldorf.de" class="auth_mail" title="E-mail the corresponding author} ; Dirk Reinhardt^q ; ^{dirk.reinhardt@uk-essen.de" class="auth_mail" title="E-mail the corresponding author} ; Jan-Henning Klusmann^r ; ^{Klusmann.Jan-Henning@mh-hannover.de" class="auth_mail" title="E-mail the corresponding author} ; Gudrun Fleischhack^q ; ^{gudrun.fleischhack@uk-essen.de" class="auth_mail" title="E-mail the corresponding author} ; Stephan Tippelt^q ; ^{stephan.tippelt@uk-essen.de" class="auth_mail" title="E-mail the corresponding author} ; Uta Dirksen^s ; ^{Uta.Dirksen@ukmuenster.de" class="auth_mail" title="E-mail the corresponding author} ; Heribert Jü ; rgens^s ; ^{jurgh@ukmuenster.de" class="auth_mail" title="E-mail the corresponding author} ; Christof M. Kramm^t ; ^{christof.kramm@med.uni-goettingen.de" class="auth_mail" title="E-mail the corresponding author} ; Andre O. von Bueren^t ; ^u ; ^{Andre.vonBuren@hcuge.ch" class="auth_mail" title="E-mail the corresponding author} ; Frank Westermann^c ; ^v ; ^{frank.westermann@Dkfz-Heidelberg.de" class="auth_mail" title="E-mail the corresponding author} ; Matthias Fischer^w ; ^x ; ^y ; ^{matthias.fischer@uk-koeln.de" class="auth_mail" title="E-mail the corresponding author} ; Birgit Burkhardt^s ; ^{birgit.burkhardt@ukmuenster.de" class="auth_mail" title="E-mail the corresponding author} ; Wilhelm Wö ; ß ; mann^z ; ^{wilhelm.woessmann@paediat.med.uni-giessen.de" class="auth_mail" title="E-mail the corresponding author} ; Michaela Nathrath^aa ; ^ab ; ^{michaela.nathrath@klinikum-kassel.de" class="auth_mail" title="E-mail the corresponding author} ; Stefan S. Bielack^ac ; ^{s.bielack@klinikum-stuttgart.de" class="auth_mail" title="E-mail the corresponding author} ; Michael C. Frü ; hwald^ad ; ^{Michael.Fruehwald@klinikum-augsburg.de" class="auth_mail" title="E-mail the corresponding author} ; Simone Fulda^c ; ^ae ; ^{Simone.Fulda@kgu.de" class="auth_mail" title="E-mail the corresponding author} ; Thomas Klingebiel^af ; ^{thomas.klingebiel@kgu.de" class="auth_mail" title="E-mail the corresponding author} ; Ewa Koscielniak^ac ; ^{E.Koscielniak@klinikum-stuttgart.de" class="auth_mail" title="E-mail the corresponding author} ; Matthias Schwab^c ; ^ag ; ^ah ; ^{Matthias.Schwab@ikp-stuttgart.de" class="auth_mail" title="E-mail the corresponding author} ; Roman Tremmel^ag ; ^ah ; ^{Roman.Tremmel@ikp-stuttgart.de" class="auth_mail" title="E-mail the corresponding author} ; Pablo Herná ; iz Driever^o ; ^{pablo.hernaiz@charite.de" class="auth_mail" title="E-mail the corresponding author} ; Johannes H. Schulte^o ; ^q ; ^{johannes.schulte@charite.de" class="auth_mail" title="E-mail the corresponding author} ; Benedikt Brors^c ; ^f ; ^g ; ^{b.brors@dkfz-heidelberg.de" class="auth_mail" title="E-mail the corresponding author} ; Andreas von Deimling^c ; ^h ; ⁱ ; ^{andreas.vondeimling@dkfz-heidelberg.de" class="auth_mail" title="E-mail the corresponding author} ; Peter Lichter^c ; ^ai ; ^{Peter.Lichter@Dkfz-Heidelberg.de" class="auth_mail" title="E-mail the corresponding author}

关键词：Personalised medicine ; Oncology ; Paediatrics ; Precision medicine ; Molecular targeted therapy ; Deep sequencing ; Cancer ; Sarcoma ; Brain

刊名：European Journal of Cancer

出版年：2016

作者：Claudia Neul¹ ; Elke Schaeffeler¹ ; Alex Sparreboom² ; Stefan Laufer³ ; Matthias Schwab¹ ; ⁴ ; ⁵ ; ^{Matthias.schwab@ikp-stuttgart.de" class="auth_mail" title="E-mail the corresponding author} ; Anne T. Nies¹

关键词：SLC transporters ; ABC transporters ; drug resistance ; tyrosine kinase inhibitors ; interindividual variability ; clinical trials ; pharmacogenomics

刊名：Trends in Pharmacological Sciences

出版年：2016

作者：Steffen W. Kluckow ; ^{steffen.kluckow@med.uni-jena.de" class="auth_mail" title="E-mail the corresponding author} ; Jan-Gerrit Rehbein ; Matthias Schwab ; Otto W. Witte ; Peter Bublak

关键词：Multiple sclerosis ; Theory of visual attention ; Visual processing capacity ; White matter ; Cognitive fatigue

刊名：Cortex

出版年：2016

作者：Fabienne Schwab^&lowast ; ; Katharina Redling^&lowast ; ; Matthias Siebert^&lowast ; ; Andy Schö ; tzau^&dagger ; ; Cora-Ann Schoenenberger^&Dagger ; ; Rosanna Zanetti-Dä ; llenbach^&lowast ; ; ^{rosanna.zanetti@usb.ch" class="auth_mail" title="E-mail the corresponding author}

关键词：Breast Imaging Reporting and Data System ; BI-RADS ; Tsukuba score ; Breast ultrasound ; Inter-observer agreement ; Intra-observer agreement ; Breast elastography

刊名：Ultrasound in Medicine & Biology

出版年：2016

作者：Antje Blank¹ ; ² ; ^{antje.blank@med.uni-heidelberg.de" class="auth_mail" title="E-mail the corresponding author} ; Christoph Markert¹ ; Nicolas Hohmann¹ ; Alexandra Carls¹ ; Gerd Mikus¹ ; Thorsten Lehr³ ; Alexander Alexandrov⁴ ; Mathias Haag⁵ ; ⁶ ; ⁷ ; Matthias Schwab⁵ ; ⁶ ; ⁷ ; ⁸ ; Stephan Urban² ; ⁹ ; Walter E. Haefeli¹ ; ²

关键词：NTCP ; sodium taurocholate co-transporting polypeptide ; HBV ; hepatitis B virus ; CHB ; chronic hepatitis B ; HDV ; hepatitis D virus ; DSMB ; data and safety monitoring board ; MABEL ; minimal anticipated biologic effect level ; AE ; adverse event ; ECG ; electrocardiogram ; CTC-AE ; common terminology criteria for adverse events ; LOQ ; limit of quantification ; NCA ; non-compartmental analysis ; NLME ; nonlinear mixed effects ; OFV ; objective function value ; BMI ; body mass index ; VPC ; visual prediction check ; AUC

刊名：Journal of Hepatology

出版年：2016

作者：Pavel Bogomolov¹ ; ² ; Alexander Alexandrov³ ; Natalia Voronkova¹ ; ² ; Maria Macievich¹ ; ² ; Ksenia Kokina¹ ; ² ; Maria Petrachenkova¹ ; ² ; Thorsten Lehr⁴ ; Florian A. Lempp⁵ ; ⁶ ; Heiner Wedemeyer⁷ ; Mathias Haag⁸ ; ⁹ ; ¹⁰ ; Matthias Schwab⁸ ; ⁹ ; ¹⁰ ; ¹¹ ; ¹² ; Walter E. Haefeli⁵ ; ¹³ ; Antje Blank⁵ ; ¹³ ; ^&dagger ; ; ^{antje.blank@med.uni-heidelberg.de" class="auth_mail" title="E-mail the corresponding author} ; Stephan Urban⁵ ; ⁶ ; ^&dagger ;

关键词：ALT ; alanine aminotransferase ; AST ; aspartate aminotransferase ; BSA ; bovine serum albumin ; blq ; below limit of quantification ; cccDNA ; covalently closed circular deoxyribonucleic acid ; CHB ; chronic hepatitis B ; CHD ; chronic hepatitis D ; d ; hepatocyte death rate ; DNA ; deoxyribonucleic acid ; HBeAg ; HBe antigen ; HBsAg ; HBs antigen ; HBV ; hepatitis B virus ; HDV ; hepatitis D virus ; IFN ; interferon ; lod ; limit of detection ; loq ; limit of quantification ; NOEL ; no observed effect level ; NLME ; non-linear

刊名：Journal of Hepatology

出版年：2016

作者：Sven Rupprecht ; MD^a ; ^{sven.rupprecht@med.uni-jena.de" class="auth_mail" title="E-mail the corresponding author} ; Sigrid Finn ; MD^a ; Jens Ehrhardt ; MSc^a ; Dirk Hoyer ; PhD^a ; Thomas Mayer ; PhD^b ; Juergen Zanow ; PhD^c ; Albrecht Guenther ; MD^a ; Matthias Schwab ; PhD^a

刊名：Journal of Vascular Surgery

出版年：2016

作者：Florian Rakers ; MD^a ; ^{florian.rakers@med.uni-jena.de" class="auth_mail" title="E-mail the corresponding author} ; Sabine Bischoff ; DVM^b ; Rene Schiffner ; MD^a ; Michelle Haase ; MD^a ; Sven Rupprecht ; MD^a ; Michael Kiehntopf ; MD ; PhD^c ; W. Nikolaus Kü ; hn-Velten ; MD ; PhD^e ; Harald Schubert ; PhD^b ; Otto W. Witte ; MD ; PhD^a ; ^d ; Mark J. Nijland ; PhD^f ; Peter W. Nathanielsz ; MD ; PhD^f ; Matthias Schwab ; MD ; PhD^a

关键词：catecholamines ; fetal programming ; fetus ; placenta ; stress transfer

刊名：American Journal of Obstetrics and Gynecology

出版年：2015