作者：Antonella Peduto^a ; ^f ; ¹ ; Maria Scuotto^a ; ¹ ; Verena Krauth^b ; ¹ ; Fiorentina Roviezzo^c ; Antonietta Rossi^c ; Veronika Temml^d ; Veronica Esposito^c ; Hermann Stuppner^d ; Daniela Schuster^e ; Bruno D'Agostino^a ; Chiara Schiraldi^a ; Mario de Rosa^a ; Oliver Werz^b ; ^{oliver.werz@uni-jena.de} ; Rosanna Filosa^a ; ^f ; ^{rosanna.filosa@unina2.it}

关键词：5-Lipoxygenase ; Quinones

刊名：European Journal of Medicinal Chemistry

出版年：2017

作者：Ulrike Garscha^a ; ¹ ; ^{ulrike.garscha@uni-jena.de" class="auth_mail" title="E-mail the corresponding author} ; Susanna Voelker^a ; ¹ ; ^{susanna.voelker@gmx.de" class="auth_mail" title="E-mail the corresponding author} ; Simona Pace^a ; ^{simona.pace@uni-jena.de" class="auth_mail" title="E-mail the corresponding author} ; Jana Gerstmeier^a ; ^{jana.gerstmeier@uni-jena.de" class="auth_mail" title="E-mail the corresponding author} ; Besa Emini^a ; ^{eminibesa@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Stefanie Liening^a ; ^{stefanie.liening@uni-jena.de" class="auth_mail" title="E-mail the corresponding author} ; Antonietta Rossi^b ; ^{antrossi@unina.it" class="auth_mail" title="E-mail the corresponding author} ; Christina Weinigel^c ; ^{christina.weinigel@med.uni-jena.de" class="auth_mail" title="E-mail the corresponding author} ; Silke Rummler^c ; ^{silke.rummler@med.uni-jena.de" class="auth_mail" title="E-mail the corresponding author} ; Ulrich S. Schubert^d ; ^e ; ^{ulrich.schubert@uni-jena.de" class="auth_mail" title="E-mail the corresponding author} ; Gerhard K.E. Scriba^a ; ^{gerhard.scriba@uni-jena.de" class="auth_mail" title="E-mail the corresponding author} ; Erşan Ç ; elikoğlu^f ; ^{ersancelikoglu@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Burcu Ç ; alışkan^f ; ^{brcaliskan@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Erden Banoglu^f ; ^{banoglu@gazi.edu.tr" class="auth_mail" title="E-mail the corresponding author} ; Lidia Sautebin^b ; ^{sautebin@unina.it" class="auth_mail" title="E-mail the corresponding author} ; Oliver Werz^a ; ^d ; ^{oliver.werz@uni-jena.de" class="auth_mail" title="E-mail the corresponding author}

关键词：5-LO ; 5-lipoxygenase ; AA ; arachidonic acid ; COX ; cyclooxygenase ; cPLA2 ; cytosolic phospholipase A2 ; FLAP ; 5-lipoxygenase-activating protein ; fMLP ; N-formyl-methionyl-leucyl-phenylalanine ; H(P)ETE ; hydro(pero)oxyeicosatetraenoic acid ; HHT ; hydroxyheptadecatrienoic acid ; IL ; interleukin ; LPS ; lipopolysaccharide ; LT ; leukotriene ; mPGES-1 ; microsomal prostaglandin E2 synthase 1 ; MPO ; myeloperoxidase ; PG ; phosphate-buffered saline plus 1  ; mg/ml glucose ; PGC ; phosphate-buffered saline plus 1 

刊名：Biochemical Pharmacology

出版年：2016

作者：Antonietta Rossi^a ; ¹ ; ^{antrossi@unina.it" class="auth_mail" title="E-mail the corresponding author} ; Simona Pace^a ; ^b ; ¹ ; ^{simona.pace@uni-jena.de" class="auth_mail" title="E-mail the corresponding author} ; Federica Tedesco^a ; ^{fed.tedesco@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Ester Pagano^a ; ^{ester.pagano@unina.it" class="auth_mail" title="E-mail the corresponding author} ; Germano Guerra^c ; ^{germano.guerra@unimol.it" class="auth_mail" title="E-mail the corresponding author} ; Fabiana Troisi^b ; ^{fabiana.troisi@uni-jena.de" class="auth_mail" title="E-mail the corresponding author} ; Markus Werner^b ; ^{werner.markus@uni-jena.de" class="auth_mail" title="E-mail the corresponding author} ; Fiorentina Roviezzo^a ; ^{fiorentina.roviezzo@unina.it" class="auth_mail" title="E-mail the corresponding author} ; Jordan K. Zjawiony^d ; ^{jordan@olemiss.edu" class="auth_mail" title="E-mail the corresponding author} ; Oliver Werz^b ; ^{oliver.werz@uni-jena.de" class="auth_mail" title="E-mail the corresponding author} ; Angelo A. Izzo^a ; ^{aaizzo@unina.it" class="auth_mail" title="E-mail the corresponding author} ; Raffaele Capasso^a ; ^{rafcapas@unina.it" class="auth_mail" title="E-mail the corresponding author}

关键词：5-LO ; 5-lipoxygenase ; AA ; arachidonic acid ; cys-LTs ; cysteinyl-leukotrienes ; DMSO ; dimethyl sulfoxide ; EIA ; enzyme immunoassay ; H&E ; hematoxylin and eosin ; HPLC ; high-performance liquid chromatography ; IL-10 ; interleukin 10 ; LPS ; lipopolysaccharide ; LT ; leukotrienes ; KOR ; k-opioid receptors ; MPO ; myeloperoxidase ; PBS ; phosphate-buffered saline ; PM ; peritoneal macrophage ; PMNLs ; polymorphonuclear leukocytes ; RIA ; radioimmunoassay ; SA ; salvinorin A ; TNF-α ; tumor necrosis factor-α

刊名：Pharmacological Research

出版年：2016

作者：Minju Kim^a ; ^&dagger ; ; Sunhoe Lee^a ; ^&dagger ; ; Eun Beul Park^a ; Kwang Jong Kim^a ; Hwi Ho Lee^b ; Ji-Sun Shin^c ; Katrin Fischer^d ; Andreas Koeberle^d ; Oliver Werz^d ; ^{oliver.werz@uni-jena.de" class="auth_mail" title="E-mail the corresponding author} ; Kyung-Tae Lee^b ; ^{ktlee@khu.ac.kr" class="auth_mail" title="E-mail the corresponding author} ; Jae Yeol Lee^a ; ^{ljy@khu.ac.kr" class="auth_mail" title="E-mail the corresponding author}

关键词：Inflammation ; Prostaglandin E2 ; Phenylsulfonyl hydrazide ; mPGES-1 ; Molecular docking study

刊名：Bioorganic & Medicinal Chemistry Letters

出版年：2016

作者：Anja M. Schaible^a ; ^{anja.schaible@gmx.de" class="auth_mail" title="E-mail the corresponding author} ; Rosanna Filosa^b ; ⁱ ; ^{rosanna.filosa@unina2.it" class="auth_mail" title="E-mail the corresponding author} ; Verena Krauth^a ; ^{verena.krauth@uni-jena.de" class="auth_mail" title="E-mail the corresponding author} ; Veronika Temml^c ; ^{Veronika.Temml@uibk.ac.at" class="auth_mail" title="E-mail the corresponding author} ; Simona Pace^a ; ^{simona.pace@uni-jena.de" class="auth_mail" title="E-mail the corresponding author} ; Ulrike Garscha^a ; ^{ulrike.garscha@uni-jena.de" class="auth_mail" title="E-mail the corresponding author} ; Stefanie Liening^a ; ^{stefanie.liening@uni-jena.de" class="auth_mail" title="E-mail the corresponding author} ; Christina Weinigel^d ; ^{christina.weinigel@med.uni-jena.de" class="auth_mail" title="E-mail the corresponding author} ; Silke Rummler^d ; ^{Silke.Rummler@med.uni-jena.de" class="auth_mail" title="E-mail the corresponding author} ; Sebastian Schieferdecker^e ; ^{sebastian.schieferdecker@leibniz-hki.de" class="auth_mail" title="E-mail the corresponding author} ; Markus Nett^e ; ^f ; ^{markus.nett@leibniz-hki.de" class="auth_mail" title="E-mail the corresponding author} ; ^{markus.nett@bci.tu-dortmund.de" class="auth_mail" title="E-mail the corresponding author} ; Antonella Peduto^b ; ^{antonellapeduto@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Selene Collarile^b ; ^{s.collarile@hotmail.it" class="auth_mail" title="E-mail the corresponding author} ; Maria Scuotto^b ; ^{mascuotto1985@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Fioretina Roviezzo^g ; ^{roviezzo@cds.unina.it" class="auth_mail" title="E-mail the corresponding author} ; Giuseppe Spaziano^b ; ^{giuseppe.spaziano@alice.it" class="auth_mail" title="E-mail the corresponding author} ; Mario de Rosa^g ; ^{mario.derosa@unina2.it" class="auth_mail" title="E-mail the corresponding author} ; Hermann Stuppner^c ; ^{hermann.stuppner@uibk.ac.at" class="auth_mail" title="E-mail the corresponding author} ; Daniela Schuster^h ; ^{Daniela.Schuster@uibk.ac.at" class="auth_mail" title="E-mail the corresponding author} ; Bruno D&rsquo ; Agostino^g ; ^{bruno.dagostino@unina2.it" class="auth_mail" title="E-mail the corresponding author} ; Oliver Werz^a ; ^{oliver.werz@uni-jena.de" class="auth_mail" title="E-mail the corresponding author}

刊名：Biochemical Pharmacology

出版年：2016

作者：Karolin Frö ; hlich ; Julia Heger ; Ann-Kathrin Fleischer ; Andre Schmidt ; Oliver Werz ; Udo R. Markert

刊名：Journal of Reproductive Immunology

出版年：2016

作者：Karolin Frö ; hlich ; Julia Heger ; Ann-Kathrin Fleischer ; Andre Schmidt ; Oliver Werz ; Udo R. Markert

刊名：Journal of Reproductive Immunology

出版年：2016

作者：Andreas Koeberle¹ ; ^{andreas.koeberle@uni-jena.de" class="auth_mail" title="E-mail the corresponding author} ; Oliver Werz ; ^{oliver.werz@uni-jena.de" class="auth_mail" title="E-mail the corresponding author}

关键词：Eicosanoid ; Micrososmal prostaglandin E2 synthase-1 ; NSAID ; Inflammation ; Lipid mediator

刊名：Biochemical Pharmacology

出版年：2015

作者：Arne Henkel^a ; ^{arne.henkel@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Lars Tausch^b ; ^{l.Tausch@yahoo.de" class="auth_mail" title="E-mail the corresponding author} ; Max Pillong^c ; ^{max.pillong@novartis.com" class="auth_mail" title="E-mail the corresponding author} ; Johann Jauch^d ; ^{j.jauch@mx.uni-saarland.de" class="auth_mail" title="E-mail the corresponding author} ; Michael Karas^b ; ^{karas@pharmchem.uni-frankfurt.de" class="auth_mail" title="E-mail the corresponding author} ; Gisbert Schneider^c ; ^{gisbert.schneider@pharma.ethz.ch" class="auth_mail" title="E-mail the corresponding author} ; Oliver Werz^e ; ^{oliver.werz@uni-jena.de" class="auth_mail" title="E-mail the corresponding author}

关键词：3-O-Acetyl-β-boswellic acid (PubChem CID ; 11 ; 386 ; 458) ; 3-O-Acetyl-11-keto-β-boswellic acid (PubChem CID ; 71 ; 463 ; 896) ; β-Boswellic acid (PubChem CID ; 168 ; 928) ; 11-Keto-β-boswellic acid (PubChem CID ; 9847548) ; Cytochalasin B (PubChem CID ; 5311281) ; N-formyl-methionyl-leucyl-phenylalanin (PubChem CID ; 4364) ; Lipopolysaccharide (PubChem CID ; 11 ; 970 ; 143) ; LL-37 (PubChem CID ; 16 ; 198 ; 951)

刊名：Pharmacological Research

出版年：2015

作者：Mayuri Napagoda ; Jana Gerstmeier ; Andreas Koeberle ; S ; ra Wesely ; Sven Popella ; Sybille Lorenz ; Kerstin Scheubert ; Sebastian B枚cker ; Ale拧 Svato拧 ; Oliver Werz

关键词：Munronia pinnata ; Inflammation ; 5-Lipoxygenase ; Radical scavenger ; Microsomal prostaglandin E2 synthase-1 ; Mass spectrometry

刊名：Journal of Ethnopharmacology

出版年：3 February, 2014