作者：Mengqing Wu^a ; ^b ; ¹ ; Dan Liu^a ; ^b ; ¹ ; Rong Zeng^a ; ^b ; ¹ ; Tao Xian^a ; ^b ; Yi Lu^a ; ^b ; Guohua Zeng^a ; ^b ; Zhangzetian Sun^c ; Bowei Huang^c ; Qiren Huang^a ; ^b ; ^{qrhuang@ncu.edu.cn}

关键词：4E-BP1 ; 4E-binding protein1 ; C/EBP ; CCAAT/ enhancer binding proteins ; EGCG ; epigallocatechin-3-gallate ; FAS ; fatty acid synthase ; FOXO1 ; forkhead box-O1 ; HFD ; high fat diet ; IGF ; insulin-like growth factor ; IR ; insulin resistance ; IRS1 ; insulin receptor substrate 1 ; MSCs ; mesenchymal stem cells ; PGC1 ; PPARγ coactivator 1 ; PI3K ; phosphatidylinositol 3 kinase ; PPARγ ; peroxisome proliferator activated receptor γ ; Rb ; retinoblastoma protein ; TG ; triglyceride ; TIF2 ; transcriptional intermediary facto

刊名：European Journal of Pharmacology

出版年：2017

作者：Victoria Obermoser^a ; ¹ ; Robert Mauersberger^a ; ¹ ; Daniela Schuster^a ; Monika Czifersky^a ; Marina Lipova^a ; Monika Siegl^a ; Ulrich Kintscher^b ; Ronald Gust^a ; ^{Ronald.Gust@uibk.ac.at}

关键词：Peroxisome proliferator-activated receptor γ ; Pharmacological profile ; Coactivator recruitment ; Transactivation assay ; Molecular modeling

刊名：European Journal of Medicinal Chemistry

出版年：2017

作者：Fan Xing¹ ; ¹⁰ ; Yizhao Luan³ ; ⁴ ; ¹⁰ ; Jing Cai¹ ; ¹⁰ ; Sihan Wu¹ ; Jialuo Mai¹ ; Jiayu Gu¹ ; Haipeng Zhang¹ ; Kai Li¹ ; Yuan Lin¹ ; Xiao Xiao¹ ; Jiankai Liang¹ ; Yuan Li¹ ; Wenli Chen¹ ; Yaqian Tan¹ ; Longxiang Sheng¹ ; Bingzheng Lu¹ ; Wanjun Lu¹ ; Mingshi Gao¹ ; Pengxin Qiu¹ ; Xingwen Su¹ ; Wei Yin⁵ ; Jun Hu⁶ ; Zhongping Chen² ; ⁷ ; Ke Sai² ; ⁷ ; Jing Wang² ; ⁷ ; Furong Chen² ; ⁷ ; Yinsheng Chen² ; ⁷ ; Shida Zhu⁸ ; Dongbing Liu⁸ ; Shiyuan Cheng⁹ ; Zhi Xie³ ; ^{xiezhi@gmail.com} ; Wenbo Zhu¹ ; ^{zhuwenbo@mail.sysu.edu.cn} ; Guangmei Yan¹ ; ² ; ¹¹ ; ^{ygm@mail.sysu.edu.cn}

关键词：glioblastoma ; induced differentiation ; Warburg effect ; metabolic reprogramming ; oxidative phosphorylation ; glycolysis ; mitochondrial biogenesis ; cyclic adenosine monophosphate ; cAMP ; PPARγ coactivator-1α ; PGC1α

刊名：Cell Reports

出版年：2017

作者：Laura Sturla^a ; ^{laurasturla@unige.it} ; Elena Mannino^a ; Sonia Scarfì ; ^b ; Santina Bruzzone^a ; Mirko Magnone^a ; Giovanna Sociali^a ; Valeria Booz^a ; Lucrezia Guida^a ; Tiziana Vigliarolo^a ; Chiara Fresia^a ; Laura Emionite^c ; Ambra Buschiazzo^d ; Cecilia Marini^e ; ^f ; Gianmario Sambuceti^d ; ^f ; Antonio De Flora^a ; Elena Zocchi^a

关键词：ABA ; abscisic acid ; ATMSC ; adipose tissue mesenchymal stem cells ; BAT ; brown adipose tissue ; CIDE-A ; cell death-inducing DNA fragmentation factor ; FAS ; fatty acid synthase ; GAPDH ; glyceraldeyde-3-phosphate dehydrogenase ; LPL ; lipoprotein lipase ; PCG-1α ; PPARγ coactivator-1α ; PRDM16 ; PR domain-containing protein 16 ; T2D ; type 2 diabetes ; TGs ; triglycerides ; TMEM26 ; transmembrane protein 26 ; UCP1 ; uncoupling protein-1 ; TBX1 ; T-box 1 ; FGF21 ; fibroblast growth factor 21 ; WAT ; white adipose tissue ; F

刊名：Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids

出版年：2017

作者：Juan Carlos Corona^a ; ^b ; Michael R. Duchen^a ; ^{m.duchen@ucl.ac.uk" class="auth_mail" title="E-mail the corresponding author}

关键词：PPARγ ; peroxisome proliferation-activated receptor gamma ; 15D-PGJ2 ; 15-deoxy-Δ12 ; 14-Prostaglandin J2 ; TZDs ; thiazolidinediones ; CNS ; central nervous system ; WAT ; white adipose tissue ; BAT ; brown adipose tissue ; SRC ; steroid receptor coactivator ; CBP ; CREB-binding protein ; AF-1 ; transcriptional activation domain ; PGC1α ; peroxisome proliferator-activated receptor gamma coactivator 1α ; TFAM ; mitochondrial transcription factor A ; mtDNA ; mitochondrial DNA ; UCP-1 ; uncoupling protein 1 ; UCP-2 ; uncoupli

刊名：Free Radical Biology and Medicine

出版年：2016

作者：Jung Seok Hwang^a ; Sun Ah Ham^a ; Taesik Yoo^a ; Won Jin Lee^a ; Kyung Shin Paek^b ; Jae-Hwan Kim^c ; Chi-Ho Lee^a ; Han Geuk Seo^a ; ^{hgseo@konkuk.ac.kr}

关键词：SIRT1 ; silent mating type information regulation 2 homolog 1 ; PPARγ ; peroxisome proliferator-activated receptor γ ; LPS ; lipopolysaccharide ; MKP-7 ; mitogen-activated protein kinase phosphatase-7 ; PGC-1α ; peroxisome proliferator-activated receptor gamma coactivator-1α ; NF-κB ; nuclear factor kappa B ; AP-1 ; activator protein-1 ; HMGB1 ; high mobility group box 1 ; JNK1 ; c-Jun N-terminal kinase 1 ; MDM2 ; mouse double minute 2 homolog ; USP-22 ; ubiquitin-specific protease-22 ; PPRE ; PPAR-response element ; S

刊名：Pharmacological Research

出版年：2016

作者：Linyuan Shen^a ; ¹ ; Yi Zhang^b ; ¹ ; Jingjing Du^a ; Li Chen^a ; Jia Luo^a ; Xuewei Li^a ; Mingzhou Li^a ; Guoqing Tang^a ; Shunhua Zhang^a ; ^{zhangsh1919@163.com" class="auth_mail" title="E-mail the corresponding author} ; Li Zhu^a ; ^{zhuli7508@163.com" class="auth_mail" title="E-mail the corresponding author}

关键词：ACS ; acyl-CoA synthetase ; C/EBPα ; CCAAT/enhancer-binding proteins ; DM ; differentiation media ; DMEM ; Dulbecco's modified Eagle's medium ; DGAT ; diacylglycerol acyltransferase ; ELOVL ; elongation-of-very-long-chain-fatty acids ; FBS ; fetal bovine serum ; FAS ; fatty acid synthase ; GSK ; glycogen synthase kinase ; LPL ; lipoprotein lipase ; miRNAs ; MicroRNAs ; PPARγ ; peroxisome proliferator activated receptor-γ coactivator ; SREBP-1 ; sterol regulatory element-binding protein-1 ; SCD-1 ; stearoyl-CoA desaturase-

刊名：Gene

出版年：2016

作者：Gou-Chun Chen^a ; Hui-Min Su^b ; Yu-Shun Lin^a ; Po-Yen Tsou^a ; Jong-Ho Chyuan^c ; Pei-Min Chao^a ; ^{pmchao@mail.cmu.edu.tw" class="auth_mail" title="E-mail the corresponding author}

关键词：ACC ; acetyl-CoA carboxylase ; ACOX ; acyl-CoA oxidase ; AMPK ; AMP-activated protein kinase ; BMSO ; bitter melon seed oil ; c9 ; t11-CLA ; cis-9 ; trans-11 isomer of conjugated linoleic acid ; α-ESA ; α-eleostearic acid ; FASN ; fatty acid synthase ; FOXO1 ; forkhead box protein O1 ; LN ; α-linolenic acid ; NAFLD ; nonalcoholic fatty liver disease ; NAMPT ; nicotinamide phosphoribosyltransferase ; PA ; punicic acid ; PGC-1α ; PPARγ coactivator 1α ; PTGR1 ; prostaglandin reductase 1 ; RETSAT ; retinol saturase ; SIRT1 ; sirtuin

刊名：Journal of Nutritional Biochemistry

出版年：2016

作者：Takashi Osumi ; ^{osumi@sci.u-hyogo.ac.jp" class="auth_mail" title="E-mail the corresponding author} ; Kenta Kuramoto¹

关键词：fatty acid ; FA ; reactive oxygen species ; ROS ; triacylglycerol ; TAG ; lipid droplet ; LD ; perilipin ; Plin ; adipose triglyceride lipase ; ATGL ; hormone sensitive lipase ; HSL ; comparative gene identification ; CGI ; diacylglycerol ; DAG ; knockout ; KO ; protein kinase A ; PKA ; neutral lipid-storage disease ; NLSD ; peroxisome proliferator-activated receptor ; PPAR ; fluorescence resonance energy transfer ; FRET ; cardiac muscle-specific ; CM ; transgenic ; Tg ; G0/G1 switch gene 2 ; G0S2 ; PPARγ coactivator ; PGC ; fatty

刊名：Experimental Cell Research

出版年：2016

作者：Nadine Gehrke¹ ; ^&dagger ; ; Marcus A. Wö ; rns¹ ; ^&dagger ; ; Yvonne Huber¹ ; Moritz Hess² ; Beate K. Straub³ ; Nadine Hö ; velmeyer⁴ ; Ari Waisman⁴ ; Yong Ook Kim⁵ ; Detlef Schuppan⁵ ; Peter R. Galle¹ ; Jö ; rn M. Schattenberg¹ ; ^{joern.schattenberg@unimedizin-mainz.de" class="auth_mail" title="E-mail the corresponding author}

关键词：NAFLD ; non-alcoholic fatty liver disease ; NF-κB ; nuclear factor-kappa B ; Bcl-3 ; B cell leukemia-3 ; NASH ; non-alcoholic steatohepatitis ; HCC ; hepatocellular carcinoma ; TNF ; tumor necrosis factor-alpha ; JNK ; c-jun N-terminal protein kinase ; PPARα ; peroxisome proliferator-activated receptor gamma ; PGC-1α ; coactivator 1α ; HFD ; high-fat ; high-carbohydrate diet ; ROS ; reactive oxygen species ; KEGG ; Kyoto Encyclopedia of Genes and Genomes

刊名：Journal of Hepatology

出版年：2016