搜索页_+mammalian+mechanistic+target+of+rapamycin

设为首页

收藏本站

网站地图 | English | 公务邮箱

读者指南

学术客户端

NSTL服务站

科技查新

外文资源

Elsevier电子期刊(35)

在“Elsevier电子期刊”中，命中：35条，耗时：0.0599381 秒

在所有数据库中总计命中：68条

1.mTOR up-regulation of PFKFB3 is essential for acute myeloid leukemia cell survival

作者：Yonghuai Feng^a ; ^b ; ^c ; ^d ; ¹ ; ^{yhfengpeking@126.com} ; Liusong Wu^e ; ¹

关键词：Acute myeloid leukemia ; mTOR ; PFKFB3

刊名：Biochemical and Biophysical Research Communications

出版年：2017

2.Energy sensing and cancer: LKB1 function and lessons learnt from Peutz-Jeghers syndrome

作者：Boris Y. Shorning ; ^{ShorningB@cf.ac.uk" class="auth_mail" title="E-mail the corresponding author} ; Alan R. Clarke

关键词：PJS ; Peutz&ndash ; Jeghers syndrome ; mTORC1 and mTORC2 ; mechanistic (mammalian) target of rapamycin complex 1 and 2 ; TGFβ ; transforming growth factor beta ; EMT ; epithelial-mesenchymal transition ; Ang II ; angiotensin II ; AMPK ; AMP-dependent protein kinase ; MARKs ; microtubule affinity-regulating kinases ; ROS ; reactive oxygen species

刊名：Seminars in Cell & Developmental Biology

出版年：2016

3.Autophagic lysosomal reformation depends on mTOR reactivation in H₂O₂-induced autophagy

作者：Jiqian Zhang^a ; ^b ; Wei Zhou^a ; ^b ; ^{zhouweid@ustc.edu.cn" class="auth_mail" title="E-mail the corresponding author} ; Jun Lin^a ; ^b ; Pengfei Wei^a ; ^b ; Yunjiao Zhang^a ; ^b ; Peipei Jin^a ; ^b ; Ming Chen^a ; ^c ; ^d ; Na Man^a ; ^b ; Longping Wen^a ; ^b ; ^{lpwen@ustc.edu.cn" class="auth_mail" title="E-mail the corresponding author}

关键词：ALR ; autophagic lysosomal reformation ; H2O2 ; hydrogen peroxide ; Rab7 ; Ras-related protein 7 ; PI4P ; phosphatidylinositol 4-phosphate ; mTOR ; mammalian mechanistic target of rapamycin ; Atg ; autophagy-related gene ; DMEM ; Dulbecco's Modified Eagle's Medium ; EBSS ; Earle's Balanced Salts Solution ; HBSS ; Hank's buffered salt solution ; PI(4 ; 5)P2 ; PI4phosphatidylinositol 4 ; 5-bisphosphate ; PIP5K ; phosphatidylinositol 4-phosphate 5-kinase

刊名：International Journal of Biochemistry and Cell Biology

出版年：2016

4.Lkb1 deletion upregulates Pax7 expression through activating Notch signaling pathway in myoblasts

作者：Tizhong Shan^a ; ^b ; ^{tzshan@zju.edu.cn" class="auth_mail" title="E-mail the corresponding author} ; Pengpeng Zhang^b ; Yan Xiong^b ; Yizhen Wang^a ; Shihuan Kuang^b ; ^c ; ^{skuang@purdue.edu" class="auth_mail" title="E-mail the corresponding author}

关键词：AMPK ; AMP-activated protein kinase ; BAT ; brown adipose tissue ; DAPT ; N-[N-(3 ; 5-difluorophenacetyl-l-alanyl)]-S-phenylglycine t-butyl ester ; FBS ; fetal bovine serum ; H&E ; hematoxylin and eosin ; Lkb1 ; Liver kinase B1 ; mTOR ; mammalian target of rapamycin ; N1ICD ; Notch1 intracellular domain ; Pax7 ; paired-box transcription factor 7 ; WAT ; white adipose tissue

刊名：International Journal of Biochemistry and Cell Biology

出版年：2016

5.The somatotropic axis and aging: Benefits of endocrine defects

作者：Andrzej Bartke^a ; ^{abartke@siumed.edu" class="auth_mail" title="E-mail the corresponding author} ; Edward O. List^b ; ^c ; John J. Kopchick^b ; ^c

关键词：Growth hormone ; Growth hormone receptors ; Longevity ; IGF-1 ; Liver ; Muscle ; Adipose tissue

刊名：Growth Hormone & IGF Research

出版年：2016

6.Ciclopirox olamine inhibits mTORC1 signaling by activation of AMPK

作者：Hongyu Zhou^a ; ^b ; ^d ; ¹ ; Chaowei Shang^b ; ^c ; ¹ ; Min Wang^a ; ^e ; Tao Shen^b ; ^c ; Lingmei Kong^a ; ^d ; Chunlei Yu^a ; ^e ; Zhennan Ye^a ; Yan Luo^b ; Lei Liu^b ; Yan Li^a ; ^d ; ^{liyanb@mail.kib.ac.cn" class="auth_mail" title="E-mail the corresponding author} ; Shile Huang^b ; ^c ; ^{shuan1@lsuhsc.edu" class="auth_mail" title="E-mail the corresponding author}

关键词：Ciclopirox ; mTOR ; AMPK ; TSC2 ; Raptor

刊名：Biochemical Pharmacology

出版年：2016

7.RhoA modulates signaling through the mechanistic target of rapamycin complex 1 (mTORC1) in mammalian cells

作者：Bradley S. Gordon ; Abid A. Kazi ; Catherine S. Coleman ; Michael D. Dennis ; Vincent Chau ; Leonard S. Jefferson ; Scot R. Kimball

关键词：4E-BP1 ; eukaryotic initiation factor 4E binding protein 1 ; caRags ; constitutively active Rags B and C ; caRheb ; constitutively active Rheb ; caRhoA ; constitutively active RhoA ; mTOR ; mechanistic target of rapamycin ; mTORC ; mechanistic target of rapamycin complex ; p70S6K1 ; 70 ; kDa ribosomal protein S6 kinase 1 ; PRAS40 ; proline-rich Akt/PKB substrate 40 ; kDa ; RAPTOR ; regulatory-associated protein of mTOR ; complex 1 ; RICTOR ; RAPTOR-independent companion of mTOR ; Sin1 ; stress-activated map kin

刊名：Cellular Signalling

出版年：March, 2014

8.Autophagy machinery in the context of mammalian mitophagy

作者：Saori R. Yoshii^a ; ^b ; Noboru Mizushima^b ; ^{nmizu@m.u-tokyo.ac.jp" class="auth_mail" title="E-mail the corresponding author}

关键词：PINK1 ; PTEN-induced putative kinase 1 ; CCCP ; carbonyl cyanide m-chlorophenylhydrazone ; OMM ; outer mitochondrial membrane ; ATG ; autophagy-related ; ULK1 ; unc-51 like kinase 1 ; FIP200 ; focal adhesion kinase family interacting protein of 200 ; kDa ; mTor ; mechanistic target of rapamycin ; PI3K ; phosphatidylinositol 3-kinase ; PI3P ; phosphatidylinositol 3-phosphate ; DFCP1 ; double-FYVE domain containing protein 1 ; SQSTM1 ; sequestosome 1 ; VMP1 ; vacuole membrane protein 1 ; WIPI ; WD-repeat protein intera

刊名：Biochimica et Biophysica Acta (BBA)-Molecular Cell Research

出版年：2015

9.The antioxidant function of sestrins is mediated by promotion of autophagic degradation of Keap1 and Nrf2 activation and by inhibition of mTORC1

作者：Sue Goo Rhee ; ^{rheesg@yuhs.ac" class="auth_mail" title="E-mail the corresponding author} ; Soo Han Bae ; ^{soohanbae@yuhs.ac" class="auth_mail" title="E-mail the corresponding author}

关键词：Sesn ; sestrin ; ROS ; reactive oxygen species ; Prx ; peroxiredoxin ; Srx ; sulfiredoxin ; ERK ; extracellular signal-regulated kinase ; Nrf2 ; nuclear factor erythroid 2-related factor 2 ; Keap1 ; Kelch-like ECH-associated protein 1 ; mTORC1 ; mechanistic target of rapamycin complex 1 ; AMPK ; AMP-activated protein kinase ; ER ; endoplasmic reticulum ; HIF-1 ; hypoxia-inducible factor-1 ; TSC ; tuberous sclerosis complex ; GAP ; GTPase-activating protein ; GATOR ; GAP activity toward Rags

刊名：Free Radical Biology and Medicine

出版年：2015

10.Mammalian target of rapamycin hyperactivity mediates the detrimental effects of a high sucrose diet on Alzheimer's disease pathology

作者：Miranda E. Orr^a ; Angelica Salinas^a ; Rochelle Buffenstein^a ; Salvatore Oddo^a ; ^b ; ^c ; ^{oddo@email.arizona.edu" class="auth_mail}

关键词：Amyloid-尾 ; APP ; Tau ; Tangles ; Insulin resistance ; Diabetes

刊名：Neurobiology of Aging

出版年：June, 2014

按检索点细分(35)

题名(2)

关键词(3)

文摘(22)

按出版年细分(35)

2027年及以后(8)

2017年(1)

2016年(5)

2015年(2)

2013年(6)

2012年(4)

2010年(1)

2009年(1)

2008年(1)

2005年(1)

2000年及以前(5)

常见问题　|　交通位置　|　联系我们　|　OA远程办公

地址：北京市海淀区学院路29号邮编：100083

电话：办公室：(+86 10)66554848；文献借阅、咨询服务、科技查新：66554700