作者：Qingyun Ren^a ; ^b ; Xinchang Liu^a ; ^b ; Zhonghua Luo^a ; Jing Li^a ; Chaolei Wang^a ; ^b ; Siegfried Goldmann^a ; ^{sigi@hecpharm.com} ; Jiancun Zhang^c ; Yingjun Zhang^a ; ^{zhangyingjun@hecpharm.com}

关键词：HBV ; Capsid assembly inhibitor ; SAR ; GLS4 ; Pharmacokinetics ; Safety evaluation

刊名：Bioorganic & Medicinal Chemistry

出版年：2017

作者：Ching-Chung Lin^a ; ^b ; Ming-Jong Bair^c ; ^d ; Chih-Jen Chen^a ; ^e ; Keng-Han Lee^b ; Ming-Jen Chen^a ; ^e ; Chia-Yuan Liu^a ; ^b ; Chen-Wang Chang^a ; ^e ; Kuang-Chun Hu^a ; ^e ; Tai-Cherng Liou^a ; ^b ; Shee-Chan Lin^a ; ^b ; Horng-Yuan Wang^a ; ^e ; Cheng-Hsin Chu^a ; ^e ; Shou-Chuan Shih^a ; ^e ; Tsang-En Wang^a ; ^b ; ^{tewang@mmh.org.tw" class="auth_mail" title="E-mail the corresponding author}

关键词：Alanine aminotransferase ; Entecavir ; Hepatitis B virus ; Lamivudine ; Telbivudine

刊名：The Kaohsiung Journal of Medical Sciences

出版年：2016

作者：Jie Wang¹ ; ^&dagger ; ; Tao Shen¹ ; ^&dagger ; ; Xiangbo Huang¹ ; ^&dagger ; ; G. Renuka Kumar² ; ^&dagger ; ; Xiangmei Chen¹ ; Zhenzhen Zeng¹ ; Ruiyang Zhang¹ ; Ran Chen¹ ; Tong Li¹ ; Tianying Zhang³ ; Quan Yuan³ ; Pao-Chen Li² ; Qi Huang² ; Richard Colonno² ; Jidong Jia⁴ ; Jinlin Hou⁵ ; Malcolm A. McCrae⁶ ; Zhiliang Gao⁷ ; ^{gaozl@21cn.com" class="auth_mail" title="E-mail the corresponding author} ; Hong Ren⁸ ; ^{renhong0531@vip.sina.com" class="auth_mail" title="E-mail the corresponding author} ; Ningshao Xia³ ; ^{nsxia@xmu.edu.cn" class="auth_mail" title="E-mail the corresponding author} ; Hui Zhuang¹ ; Fengmin Lu¹ ; ^{lu.fengmin@hsc.pku.edu.cn" class="auth_mail" title="E-mail the corresponding author}

关键词：HBV ; hepatitis B virus ; cccDNA ; covalently closed circular DNA ; pgRNA ; pregenome RNA ; NAs ; nucleot(s)ide analogues ; CHB ; chronic hepatitis B ; HCC ; hepatocellular carcinoma ; ETV ; entecavir ; LMV ; lamivudine ; EoT ; end of treatment ; ADV ; adefovir dipivoxil ; LdT ; telbivudine

刊名：Journal of Hepatology

出版年：2016

作者：Mingze Su ; Kuanhui Xiang ; Yao Li ; Yutang Li ; Juan Deng ; Xizhan Xu ; Ling Yan ; Hui Zhuang ; ^{zhuangbmu@126.com" class="auth_mail" title="E-mail the corresponding author} ; Tong Li ; ^{tongli08@vip.sina.com" class="auth_mail" title="E-mail the corresponding author}

关键词：AA ; amino acid ; ADV ; adefovir dipivoxil ; CHB ; chronic hepatitis B ; HBeAg ; hepatitis B e antigen ; HBsAg ; hepatitis B surface antigen ; HBV ; hepatitis B virus ; HIV ; human immunodeficiency virus ; HSPGs ; highly sulfated heparan sulfate proteoglycans ; LdT ; telbivudine ; LMV ; lamivudine ; MHR ; major hydrophilic region ; NAs ; nucleos(t)ide analogs ; NAr ; nucleos(t)ide analog resistance ; RT ; reverse transcriptase ; S ; surface

刊名：Infection, Genetics and Evolution

出版年：2016

作者：Youyun Zhao^a ; ^b ; ^{zhaoyy206@163.com" class="auth_mail" title="E-mail the corresponding author} ; Jianhua Wu^a ; ^{hjw1959@vip.sina.com" class="auth_mail" title="E-mail the corresponding author} ; Lijun Sun^c ; ^{Sun8882005@163.com" class="auth_mail" title="E-mail the corresponding author} ; Guangzhong Liu^a ; Bo Li^a ; Yi Zheng^a ; Xiaodong Li^d ; Junxiu Tao^d

关键词：Hepatitis B virus ; Chronic hepatitis B ; Viral resistance mutations

刊名：The Brazilian Journal of Infectious Diseases

出版年：2016

作者：Panpan Yi ; Ruochan Chen ; Yan Huang ; Rong-Rong Zhou ; ^{rr_xy1234@126.com" class="auth_mail" title="E-mail the corresponding author} ; Xue-Gong Fan ; ^{xgfan@hotmail.com" class="auth_mail" title="E-mail the corresponding author}

关键词：HBV ; hepatitis B virus ; HBI ; Ghepatitis B immunoglobulin ; MTCT ; mother to child transmission ; HCC ; hepatocellular carcinoma ; HBIG ; hepatitis B immunoglobulin ; HBsAg ; hepatitis Bs antigen ; HBeAg ; hepatitis Be antigen ; WHO ; World Health Organization ; PBMC ; peripheral blood mononuclear cell ; EASL ; European Association for the Study of the Liver ; APASL ; the Asian Pacific Association for the Study of the Liver ; AASLD ; American Association for the Study of Liver Diseases (AASLD)

刊名：Journal of Clinical Virology

出版年：2016

作者：Da-biao Chen ; You-ming Chen ; Jing Liu ; Dong-ying Xie ; Cui-rong Lu ; Zhan-lian Huang ; Rui-hua Zhu ; Zhi-liang Gao

关键词：CHB ; Telbivudine ; Withdraw ; Durability ; Relapse

刊名：Journal of Clinical Virology

出版年：January, 2014

作者：Yuankai Wu^a ; ^b ; ¹ ; Yusheng Jie^a ; ^b ; ¹ ; Xiangyong Li^a ; ^b ; Mingxing Huang^a ; ^b ; Xinhua Li^a ; ^b ; Hong Shi^a ; ^b ; Shuru Chen^a ; ^b ; Min Zhang^a ; ^b ; Yunlong Ao^a ; ^b ; Fangji Yang^a ; ^b ; Zhiliang Gao^a ; ^b ; Guoli Lin^a ; ^b ; ² ; ^{Lingshanxiaoxianzi@sina.com.cn" class="auth_mail" title="E-mail the corresponding author} ; Yutian Chong^a ; ^b ; ³ ; ^{ytchong2005@126.com" class="auth_mail" title="E-mail the corresponding author}

刊名：Clinics and Research in Hepatology and Gastroenterology

出版年：2016

作者：Hongyan Diao^a ; ^b ; ^{diaohy@zju.edu.cn" class="auth_mail} ; Jianqin He^a ; ^b ; Qishi Zheng^c ; Jianing Chen^a ; ^b ; Guangying Cui^a ; ^b ; Yingfeng Wei^a ; ^b ; Ping Ye^a ; Masashi Kohanawa^d ; Lanjuan Li^a ; ^b ; ^{ljli@zju.edu.cn" class="auth_mail}

关键词：NKT-like cells ; Chronic hepatitis B ; IL-17 ; Telbivudine treatment

刊名：Immunology Letters

出版年：July 2014

作者：Aurelio Herná ; ndez-Laí ; n^f ; ^{aurelio.hlain@salud.madrid.org" class="auth_mail" title="E-mail the corresponding author} ; Antonio Mé ; ndez Guerrero^a ; ^{mendezguerrero.antonio@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Cristina Domí ; nguez-Gonzá ; lez^b ; ^d ; ^{c.dom.glez@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Inmaculada Ferná ; ndez-Vá ; zquez^e ; ^{ifvazquez@salud.madrid.org" class="auth_mail" title="E-mail the corresponding author} ; David Gata Maya^a ; ^{david.gata@hotmail.com" class="auth_mail" title="E-mail the corresponding author} ; Aitor Delmiro^c ; ^d ; ^{adelmiro@h12o.es" class="auth_mail" title="E-mail the corresponding author} ; Joaquí ; n Arenas^c ; ^d ; ^{joaquin.arenas@salud.madrid.org" class="auth_mail" title="E-mail the corresponding author} ; Juan Ruiz Morales^a ; ^{jmruiz54@yahoo.es" class="auth_mail" title="E-mail the corresponding author} ; Alberto Blá ; zquez^c ; ^d ; ¹ ; ^{abencinar@hotmail.com" class="auth_mail" title="E-mail the corresponding author} ; Marí ; a Moran^c ; ^d ; ¹ ; ^{mmoran@h12o.es" class="auth_mail" title="E-mail the corresponding author} ; Miguel A. Martí ; n^c ; ^d ; ^{mamcasanueva@h12o.es" class="auth_mail" title="E-mail the corresponding author}

关键词：Muscle disease ; Mitochondrial disorders ; Toxicology ; Genetics

刊名：Journal of the Neurological Sciences

出版年：2015