作者：Gwyneth Zai^a ; ^b ; ^c ; ^d ; ^{gwyneth.zai@camh.ca} ; Trevor W. Robbins^c ; ^e ; Barbara J. Sahakian^c ; ^d ; James L. Kennedy^a ; ^b

关键词：Genetics ; Schizophrenia ; Neurocognition ; Cognitive deficits ; Candidate gene studies ; Genome-wide association studies (GWASs)

刊名：Neuroscience & Biobehavioral Reviews

出版年：2017

作者：Paraskevi Chairta ; Paschalis Nicolaou ; Kyproula Christodoulou ; ^{roula@cing.ac.cy}

关键词：ACA ; anti-centromere antibody ; AID ; autoimmune disease ; ARA ; anti-RNA polymerase III antibody ; ATA ; anti-topoisomerase I antibody ; SSc ; systemic sclerosis ; dcSSc ; diffused cutaneous SSc ; lcSSc ; limited cutaneous SSc ; GWAS ; Genome Wide Association Study ; HLA ; human leukocyte antigen ; MHC ; major histocompatibility complex ; PAH ; pulmonary arterial hypertension ; RA ; rheumatoid arthritis ; SLE ; systemic lupus erythematosus ; VNTRs ; variable number tandem repeats

刊名：Human Immunology

出版年：2017

作者：Moritz von Scheidt¹ ; Yuqi Zhao² ; Zeyneb Kurt² ; Calvin Pan³ ; Lingyao Zeng¹ ; Xia Yang² ; Heribert Schunkert¹ ; ⁴ ; Aldons J. Lusis³ ; ^{jlusis@mednet.ucla.edu}

关键词：genome-wide association studies ; engineered mouse models ; CAD risk factors ; passenger genes ; common and complex disease ; pathway modeling ; lesions analysis ; lipoprotein metabolism ; mouse atherosclerosis genes ; diabetes

刊名：Cell Metabolism

出版年：2017

作者：Ning Ye ; Shuquan Rao ; Tingfu Du ; Huiling Hu ; Zeyue Liu ; Yan Shen ; Qi Xu ; ^{xuqi@pumc.edu.cn}

关键词：GWA studies ; genome-wide association studies ; SNP ; single nucleotide polymorphism ; MDD ; major depressive disorder ; TAS ; trait/disease-associated SNP ; lncRNA ; long noncoding RNA ; DSM-IV ; Diagnostic and Statistical Manual of Mental Disorders Fourth Edition ; HAMD-17 ; 17-item Hamilton Rating Scale for Depression ; χ2 ; chi-square ; HWE ; Hardy&ndash ; Weinberg equilibrium ; FC ; fold change ; MAF ; minor allele frequency ; LncRNA Disease ; LncRNA And Disease Database ; BDNF-AS ; brain-derived neurotrophic factor

刊名：Gene

出版年：2017

作者：Charlotte Wang^a ; Fabrizio Ruggeri^b ; Chuhsing K. Hsiao^c ; Raffaele Argiento^b ; ^d ; ^{raffaele@mi.imati.cnr.it}

关键词：Bayesian Clustering ; Bayesian Nonparametric ; Random partitions ; Dirichlet process mixture model ; GWAS ; Logistic regression

刊名：International Journal of Approximate Reasoning

出版年：2017

作者：Gaelle R. Carrat¹ ; Ming Hu¹ ; Marie-Sophie Nguyen-Tu¹ ; Pauline Chabosseau¹ ; Kyle J. Gaulton² ; ³ ; Martijn van de Bunt² ; ⁴ ; Afshan Siddiq⁵ ; Mario Falchi⁵ ; ⁶ ; Matthias Thurner² ; ⁴ ; Mickaë ; l Canouil⁷ ; ⁸ ; Francois Pattou⁷ ; ⁸ ; Isabelle Leclerc¹ ; Timothy J. Pullen¹ ; Matthew C. Cane¹ ; Priyanka Prabhala¹ ; William Greenwald² ; ³ ; Anke Schulte⁹ ; Piero Marchetti¹⁰ ; Mark Ibberson¹¹ ; Patrick E. MacDonald¹² ; Jocelyn E. Manning Fox¹² ; Anna L. Gloyn² ; ⁴ ; ¹³ ; Philippe Froguel⁵ ; ⁷ ; ⁸ ; Michele Solimena¹⁴ ; ¹⁵ ; ¹⁶ ; Mark I. McCarthy² ; ⁴ ; ¹³ ; Guy A. Rutter¹ ; ^{g.rutter@imperial.ac.uk}

关键词：diabetes ; insulin ; islet ; mouse ; genetics ; GWAS ; secretion ; STARD10 ; ARAP1

刊名：The American Journal of Human Genetics

出版年：2017

作者：Manvi Vernekar^a ; ^{manviv8@gmail.com} ; Deepak Amarapurkar^b ; ^{amarapurkar@gmail.com} ; Kalpana Joshi^c ; ^{joshikalpana@gmail.com} ; Rekha Singhal^a ; ^{rsinghal7@rediffmail.com} ; ^{rs.singhal@ictmumbai.edu.in}

关键词：NAFLD ; nonalcoholic fatty liver disease ; MetS ; metabolic syndrome ; PUFAs ; polyunsaturated fatty acids ; CAD ; coronary artery disease ; CVD ; cardiovascular disease ; PNPLA3 ; patatin-like phospholipase domain containing protein-3 ; GWAS ; genome wide association studies ; D6D ; delta-6-desaturases ; D5D ; delta-5-desaturases ; ACS ; acute coronary syndrome ; PCR ; polymerase chain reaction ; RFLP ; restriction fragment length polymorphism ; AST ; aspartate aminotransferase ; ALT ; alanine aminotransferase ; ALP ; alka

刊名：Meta Gene

出版年：2017

作者：Anton M. Schwartz^a ; Denis E. Demin^b ; Ilya E. Vorontsov^c ; Artem S. Kasyanov^c ; Lidia V. Putlyaeva^a ; Karina A. Tatosyan^a ; Ivan V. Kulakovskiy^a ; ^c ; Dmitry V. Kuprash^a ; ^b ; ^d ; ^{kuprash@eimb.ru}

关键词：IL2RA ; interleukin-2-receptor alpha ; SNP ; single nucleotide polymorphism ; TF ; transcription factor ; LTi cell ; lymphoid tissue inducer cell ; GWAS ; Genome-wide association studies

刊名：Gene

出版年：2017

作者：Ares Pasipoularides¹ ; ^{apasipou@duke.edu}

关键词：Personalized/precise medicine ; DNA microarrays ; Next-generation genome sequencing (NGS) ; Genome-wide association studies (GWAS) ; CRISPR-Cas9 genetic&ndash ; phenotypic screen ; Molecular genomic decoding of phenotypic diversity ; Omics-based tests ; Molecular genetic biomarkers ; Pharmacogenomics and pharmacogenetics

刊名：International Journal of Cardiology

出版年：2017

作者：Evangelia Eirini Tsermpini^a ; Yanfei Zhang^b ; ^c ; Paola Niola^d ; Caterina Chillotti^e ; Raffaella Ardau^e ; Alberto Bocchetta^e ; George P. Patrinos^a ; Maria Del Zompo^d ; ^e ; Giovanni Severino^d ; ^{severino@unica.it} ; Ming Ta Michael Lee^b ; ^c ; ^{mlee2@geisinger.edu} ; Alessio Squassina^d ; ^{squassina@unica.it}

关键词：ACCN1 gene ; Acid Sensing Ion Channel Neurona-1 gene ; ASICs ; Acid sensing ion channels ; BD ; Bipolar disorder ; BD I ; Bipolar disorder I ; BD II ; Bipolar disorder II ; CKD ; chronic kidney disease ; DEG/ENaC super family ; degenerin/epithelial sodium channel super family ; DSM-IV ; Diagnostic and Statistical Manual of Mental Disorders ; 4th Edition ; ERF ; established renal failure ; eGFR ; estimated glomerular filtration rate ; GWAS ; genome-wide association studies ; GFR ; glomerular filtration rate ; HWE ; Hardy

刊名：Neuroscience Letters

出版年：2017